Issue 2, 2020

Dynamic DNA nanotechnology: toward functional nanoscale devices

Abstract

Dynamic DNA nanotechnology involves the creation of nanoscale devices made of DNA whose primary function arises from their ability to undergo controlled motion or reconfiguration. In the past two decades, dynamic DNA nanotechnology has evolved to the point where it is now being employed in devices intended for applications in sensing, drug delivery, computation, nanorobotics, and more. In this review article, we discuss the design of dynamic DNA nanodevices and the characterization and prediction of device behavior. We also identify a number of continuing challenges in dynamic DNA nanotechnology and discuss potential solutions to those challenges.

Graphical abstract: Dynamic DNA nanotechnology: toward functional nanoscale devices

Article information

Article type
Review Article
Submitted
08 Aug. 2019
Accepted
15 Okt. 2019
First published
15 Okt. 2019

Nanoscale Horiz., 2020,5, 182-201

Author version available

Dynamic DNA nanotechnology: toward functional nanoscale devices

M. DeLuca, Z. Shi, C. E. Castro and G. Arya, Nanoscale Horiz., 2020, 5, 182 DOI: 10.1039/C9NH00529C

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