Issue 22, 2019

Recent advances in gold nanoparticles for biomedical applications: from hybrid structures to multi-functionality

Abstract

Gold nanoparticles (Au NPs) are arguably the most versatile nanomaterials reported to date. Recent advances in nanofabrication and chemical synthesis have expanded the scope of Au NPs from classical homogeneous nanospheres to a wide range of hybrid nanostructures with programmable size, shape and composition. Novel physiochemical properties can be achieved via design and engineering of the hybrid nanostructures. In this review we discuss the recent progress in the development of complex hybrid Au NPs and propose a classification framework based on three fundamental structural dimensions (length scale, complexity and symmetry) to aid categorising, comparing and designing various types of Au NPs. Their novel functions and potential for biomedical applications will also be discussed, featuring point-of-care diagnostics by advanced optical spectroscopy and assays, as well as minimally invasive surgeries and targeted drug delivery using multifunctional nano-robots.

Graphical abstract: Recent advances in gold nanoparticles for biomedical applications: from hybrid structures to multi-functionality

Article information

Article type
Review Article
Submitted
21 Marts 2019
Accepted
14 Maijs 2019
First published
14 Maijs 2019
This article is Open Access
Creative Commons BY license

J. Mater. Chem. B, 2019,7, 3480-3496

Recent advances in gold nanoparticles for biomedical applications: from hybrid structures to multi-functionality

H. Jeong, E. Choi, E. Ellis and T. Lee, J. Mater. Chem. B, 2019, 7, 3480 DOI: 10.1039/C9TB00557A

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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