Issue 37, 2019

Novel diagnostics for point-of-care bacterial detection and identification

Abstract

In addition to limiting the effectiveness of antimicrobial agents, antimicrobial resistance (AMR) is a significant global health concern as it is responsible for significant mortality/morbidity and increased economic burdens on healthcare systems. Diagnostic tests have been suggested as a means of prolonging the effectiveness of current antimicrobials; culture and other conventional diagnostics are hindered in their practicality as they are time- and labour intensive to perform. Point-of-care (POC) testing is performed near where the patient is being treated and can provide timely results that allow evidence based clinical interventions to be made. This review aims to outline the chemical principles behind some novel and emerging diagnostic techniques which have the required speed, simplicity, effectiveness and low-cost for incorporation into POC devices which can be used to inform and optimize antimicrobial use.

Graphical abstract: Novel diagnostics for point-of-care bacterial detection and identification

Article information

Article type
Review Article
Submitted
26 Apr. 2019
Accepted
30 Jūn. 2019
First published
10 Jūl. 2019
This article is Open Access
Creative Commons BY-NC license

RSC Adv., 2019,9, 21486-21497

Novel diagnostics for point-of-care bacterial detection and identification

S. Reali, E. Y. Najib, K. E. Treuerné Balázs, A. Chern Hui Tan, L. Váradi, D. E. Hibbs and P. W. Groundwater, RSC Adv., 2019, 9, 21486 DOI: 10.1039/C9RA03118A

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