Issue 7, 2019

Mechanism of nitrones and allenoates cascade reactions for the synthesis of dihydro[1,2-a]indoles

Abstract

Quantum mechanical calculations (DLPNO-CCSD(T) and dispersion-corrected DFT) are employed to gain insights into the mechanism and selectivity in the catalytic synthesis of dihydropyrido[1,2-a]indoles from the cascade reaction between nitrones and allenes. Implications for controlling diverging pathways is discussed.

Graphical abstract: Mechanism of nitrones and allenoates cascade reactions for the synthesis of dihydro[1,2-a]indoles

Supplementary files

Article information

Article type
Communication
Submitted
21 Sept. 2018
Accepted
14 Nov. 2018
First published
14 Nov. 2018

Org. Biomol. Chem., 2019,17, 1767-1772

Author version available

Mechanism of nitrones and allenoates cascade reactions for the synthesis of dihydro[1,2-a]indoles

W. Lee, M. Yuan, C. Acha, A. Onwu and O. Gutierrez, Org. Biomol. Chem., 2019, 17, 1767 DOI: 10.1039/C8OB02346H

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements