Coline Jumeaux, Eunjung Kim, Philip D. Howes, Hyemin Kim, Rona Chandrawati and Molly M. Stevens
Nanoscale Adv., 2019,1, 532-536
DOI:
10.1039/C8NA00331A,
Communication
Open Access Learn more..We report the specific and sensitive detection of microRNA using an inverse DNA-mediated liposome fusion assay. This assay is homogeneous, and does not require washing, separation, or enzyme-associated amplification steps. By fine-tuning the surface functionalisation of the liposomes, liposome concentration, and assay temperature, we demonstrated a sub-nanomolar limit of detection for the target.
