Issue 5, 2019

A new polymorph of the common coformer isonicotinamide

Abstract

A sixth polymorph of isonicotinamide was serendipitously discovered during an attempt to co-crystallize allopurinol with isonicotinamide in chloroform. A single crystal X-ray diffraction study indicated that this form crystallizes in the orthorhombic space group Pca21 and its uniqueness was further confirmed by comparison with the crystal structures of the other five known forms of isonicotinamide. Further characterization of the new polymorph included thermal analysis.

Graphical abstract: A new polymorph of the common coformer isonicotinamide

Supplementary files

Article information

Article type
Paper
Submitted
17 Sept. 2018
Accepted
19 Dec. 2018
First published
20 Dec. 2018

CrystEngComm, 2019,21, 843-849

A new polymorph of the common coformer isonicotinamide

A. I. Vicatos and M. R. Caira, CrystEngComm, 2019, 21, 843 DOI: 10.1039/C8CE01588K

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