Issue 26, 2019

Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides

Abstract

The first example of an intramolecular hydroarylation of 1,6-en-α-chloro-enamides was achieved by a palladium-catalysed ligand-free reductive Heck cycloisomerisation with no competing Heck-cyclised by-product.

Graphical abstract: Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides

Supplementary files

Article information

Article type
Communication
Submitted
21 Janv. 2019
Accepted
04 Marts 2019
First published
04 Marts 2019

Chem. Commun., 2019,55, 3733-3736

Palladium-catalysed ligand-free reductive Heck cycloisomerisation of 1,6-en-α-chloro-enamides

Y. Hou, J. Ma, H. Yang, E. A. Anderson, A. Whiting and N. Wu, Chem. Commun., 2019, 55, 3733 DOI: 10.1039/C9CC00537D

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