Issue 56, 2018

Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways

Abstract

A highly efficient metal free approach for the oxidation of primary and secondary amines to their corresponding aldehydes and ketones using PhI(OAc)2 in combination with a catalytic amount of TEMPO as an oxidizing agent is described. This protocol is rapid and provides diverse products under milder reaction conditions in excellent yields. In addition, the mechanistic study is well demonstrated by spectroscopic methods.

Graphical abstract: Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways

Supplementary files

Article information

Article type
Paper
Submitted
06 Sept. 2018
Accepted
08 Sept. 2018
First published
14 Sept. 2018
This article is Open Access
Creative Commons BY license

RSC Adv., 2018,8, 32055-32062

Metal-free hypervalent iodine/TEMPO mediated oxidation of amines and mechanistic insight into the reaction pathways

A. H. Bansode and G. Suryavanshi, RSC Adv., 2018, 8, 32055 DOI: 10.1039/C8RA07451H

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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