Issue 83, 2018

Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)

Abstract

Up until now, molecular chelating agents, such as diethylenetriamine pentaacetic acid (DTPA), have been the standard method for actinide human decorporation. Mainly active in blood serum, their distribution within the body is thus limited. To treat a wider range of organs affected by plutonium contamination, a potential new class of macromolecular decorporation agents is being studied. Polyethyleneimine methylenecarboxylate (PEI-MC) is one such example. It is being considered here because of its capacity for targeting the liver and bones.

Graphical abstract: Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(iv)

Supplementary files

Article information

Article type
Communication
Submitted
29 Jūn. 2018
Accepted
24 Sept. 2018
First published
25 Sept. 2018

Chem. Commun., 2018,54, 11705-11708

Polyethyleneimine methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(IV)

F. Lahrouch, B. Siberchicot, L. Leost, J. Aupiais, A. Rossberg, C. Hennig, C. Den Auwer and C. Di Giorgio, Chem. Commun., 2018, 54, 11705 DOI: 10.1039/C8CC05206A

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