Issue 37, 2017

Regioselective thiolation of electron rich arenes and heterocycles in recyclable catalytic media

Abstract

A convenient and novel approach has been developed for the synthesis of unsymmetrical diaryl sulfides by the reaction of sulfonyl hydrazides with phenols using a [Bmim][Br] ionic liquid through the formation of C–S bonds. The reaction has further been extended to indole, β-naphthol and aromatic amine moieties. This protocol offers a new, versatile and greener approach for thiolation of natural phenols (monoterpenes)/aromatic phenols/β-naphthols/aromatic amines and indoles without using any catalyst. A broad range of functional groups were well tolerated in this reaction system.

Graphical abstract: Regioselective thiolation of electron rich arenes and heterocycles in recyclable catalytic media

Supplementary files

Article information

Article type
Paper
Submitted
25 Febr. 2017
Accepted
17 Apr. 2017
First published
25 Apr. 2017
This article is Open Access
Creative Commons BY license

RSC Adv., 2017,7, 22860-22868

Regioselective thiolation of electron rich arenes and heterocycles in recyclable catalytic media

D. S. Raghuvanshi and N. Verma, RSC Adv., 2017, 7, 22860 DOI: 10.1039/C7RA02350B

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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