Issue 6, 2017

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Abstract

We report a reversible off/on fluorescent probe for monitoring concentration changes of sulfane sulfur by utilizing the unique ability of sulfane sulfur to bind reversibly to other sulfur atoms and the intramolecular spirocyclization reaction of xanthene dyes. It reversibly visualized sulfane sulfur in living A549 cells and primary-cultured hippocampal astrocytes.

Graphical abstract: Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Supplementary files

Article information

Article type
Communication
Submitted
18 Okt. 2016
Accepted
17 Dec. 2016
First published
19 Dec. 2016
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2017,53, 1064-1067

Development of a reversible fluorescent probe for reactive sulfur species, sulfane sulfur, and its biological application

Y. Takano, K. Hanaoka, K. Shimamoto, R. Miyamoto, T. Komatsu, T. Ueno, T. Terai, H. Kimura, T. Nagano and Y. Urano, Chem. Commun., 2017, 53, 1064 DOI: 10.1039/C6CC08372B

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