Issue 6, 2016

Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions

Abstract

A rapid, chemoselective and metal-free C–B bond-forming reaction of aryl iodides and bromides in aqueous solution at low temperatures was discovered. This reaction is amenable to batch and continuous-flow conditions and shows exceptional functional group tolerance and broad substrate scope regarding both the aryl halide and the borylating reagent. Initial mechanistic experiments indicated a photolytically generated aryl radical as the key intermediate.

Graphical abstract: Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions

Supplementary files

Article information

Article type
Edge Article
Submitted
25 Nov. 2015
Accepted
30 Janv. 2016
First published
01 Febr. 2016
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2016,7, 3676-3680

Author version available

Efficient metal-free photochemical borylation of aryl halides under batch and continuous-flow conditions

K. Chen, S. Zhang, P. He and P. Li, Chem. Sci., 2016, 7, 3676 DOI: 10.1039/C5SC04521E

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements