Issue 1, 2016

Dual gold/photoredox-catalyzed C(sp)–H arylation of terminal alkynes with diazonium salts

Abstract

The arylation of alkyl and aromatic terminal alkynes by a dual gold/photoredox catalytic system is described. Using aryldiazonium salts as readily available aryl sources, a range of diversely-functionalized arylalkynes could be synthesized under mild, base-free reaction conditions using visible light from simple household sources or even sunlight. This process, which exhibits a broad scope and functional group tolerance, expands the range of transformations amenable to dual gold/photoredox catalysis to those involving C–H bond functionalization and demonstrates the potential of this concept to access AuI/AuIII redox chemistry under mild, redox-neutral conditions.

Graphical abstract: Dual gold/photoredox-catalyzed C(sp)–H arylation of terminal alkynes with diazonium salts

Supplementary files

Article information

Article type
Edge Article
Submitted
16 Jūl. 2015
Accepted
07 Okt. 2015
First published
08 Okt. 2015
This article is Open Access

All publication charges for this article have been paid for by the Royal Society of Chemistry
Creative Commons BY license

Chem. Sci., 2016,7, 89-93

Dual gold/photoredox-catalyzed C(sp)–H arylation of terminal alkynes with diazonium salts

A. Tlahuext-Aca, M. N. Hopkinson, B. Sahoo and F. Glorius, Chem. Sci., 2016, 7, 89 DOI: 10.1039/C5SC02583D

This article is licensed under a Creative Commons Attribution 3.0 Unported Licence. You can use material from this article in other publications without requesting further permissions from the RSC, provided that the correct acknowledgement is given.

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