Issue 98, 2016

Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes

Abstract

To expand the toolbox of fluorescent protein-based voltage indicators, we explored two distinct protein design strategies. Using these design strategies, we created three new voltage indicators: a red intensiometric voltage indicator (tdFlicR Δ110AR), a green/red ratiometric voltage indicator (tdFlicR-VK-ASAP), and a green to red photoconvertible voltage indicator (FlicGR1).

Graphical abstract: Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes

Supplementary files

Article information

Article type
Communication
Submitted
19 Aug. 2016
Accepted
14 Nov. 2016
First published
14 Nov. 2016
This article is Open Access
Creative Commons BY-NC license

Chem. Commun., 2016,52, 14153-14156

Ratiometric and photoconvertible fluorescent protein-based voltage indicator prototypes

A. S. Abdelfattah, V. Rancic, B. Rawal, K. Ballanyi and R. E. Campbell, Chem. Commun., 2016, 52, 14153 DOI: 10.1039/C6CC06810C

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