Issue 34, 2016

An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Abstract

This communication reports a new nanocatalytic scheme based on the facts that the redox reaction between a highly outer-sphere-reaction-philic (OSR-philic) species and a highly inner-sphere-reaction-philic (ISR-philic) species is slow and that an OSR- and ISR-philic Au-nanocatalyst label can mediate the two different types of redox species. This scheme allows highly sensitive and incubation free detection of creatine kinase-MB.

Graphical abstract: An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

Supplementary files

Article information

Article type
Communication
Submitted
14 Janv. 2016
Accepted
29 Marts 2016
First published
07 Apr. 2016

Chem. Commun., 2016,52, 5884-5887

An ultrasensitive and incubation-free electrochemical immunosensor using a gold-nanocatalyst label mediating outer-sphere-reaction-philic and inner-sphere-reaction-philic species

C. S. Fang, K. H. Oh, A. Oh, K. Lee, S. Park, S. Kim, J. K. Park and H. Yang, Chem. Commun., 2016, 52, 5884 DOI: 10.1039/C6CC00353B

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