Issue 7, 2015

Raman spectroscopic studies of vitamin A content in the liver: a biomarker of healthy liver

Abstract

Confocal Raman microspectroscopy was used in this study to identify hepatic stellate cells (HSCs) from healthy mice and mice with untreated and treated liver steatosis. We have identified the main form of occurrence of vitamin A in healthy liver and confirmed its absence in the pathological state. Additionally, we have reported the reappearance of vitamin A in the tissue after treatment of liver steatosis.

Graphical abstract: Raman spectroscopic studies of vitamin A content in the liver: a biomarker of healthy liver

Article information

Article type
Communication
Submitted
17 Okt. 2014
Accepted
09 Dec. 2014
First published
09 Dec. 2014

Analyst, 2015,140, 2074-2079

Author version available

Raman spectroscopic studies of vitamin A content in the liver: a biomarker of healthy liver

K. Kochan, K. M. Marzec, E. Maslak, S. Chlopicki and M. Baranska, Analyst, 2015, 140, 2074 DOI: 10.1039/C4AN01878H

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