Issue 10, 2014
From the journal:

Organic Chemistry Frontiers

Acenaphthoimidazolium chloride-enabled nickel-catalyzed amination of bulky aryl tosylates†‡

Jian Jiang,a   Haibo Zhu,a   Yajing Shena  and  Tao Tu*a  

* Corresponding authors

a Department of Chemistry, Fudan University, 220 Handan Road, Shanghai, China
E-mail: taotu@fudan.edu.cn

Abstract

A robust catalyst derived from NiCl2·(DME) and acenaphthoimidazolium chloride exhibited high activity towards the challenging amination of bulky and heterocyclic aryl tosylates with secondary amines under mild reaction conditions at 2 mol% catalyst loading within 3 hours. Further, a wide range of primary amines were also successfully mono-aminated by our newly developed protocol.

Graphical abstract: Acenaphthoimidazolium chloride-enabled nickel-catalyzed amination of bulky aryl tosylates

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C4QO00233D
Article type
Research Article
Submitted
22 Aug. 2014
Accepted
14 Sept. 2014
First published
15 Sept. 2014

Org. Chem. Front., 2014,1, 1172-1175

Author version available

Download author version (PDF)

Permissions

Request permissions

Acenaphthoimidazolium chloride-enabled nickel-catalyzed amination of bulky aryl tosylates

J. Jiang, H. Zhu, Y. Shen and T. Tu, Org. Chem. Front., 2014, 1, 1172 DOI: 10.1039/C4QO00233D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements