Issue 13, 2014

Microfluidic spinning of micro- and nano-scale fibers for tissue engineering

Abstract

Microfluidic technologies have recently been shown to hold significant potential as novel tools for producing micro- and nano-scale structures for a variety of applications in tissue engineering and cell biology. Over the last decade, microfluidic spinning has emerged as an advanced method for fabricating fibers with diverse shapes and sizes without the use of complicated devices or facilities. In this critical review, we describe the current development of microfluidic-based spinning techniques for producing micro- and nano-scale fibers based on different solidification methods, platforms, geometries, or biomaterials. We also highlight the emerging applications of fibers as bottom-up scaffolds such as cell encapsulation or guidance for use in tissue engineering research and clinical practice.

Graphical abstract: Microfluidic spinning of micro- and nano-scale fibers for tissue engineering

Article information

Article type
Critical Review
Submitted
20 Dec. 2013
Accepted
05 Febr. 2014
First published
05 Febr. 2014

Lab Chip, 2014,14, 2145-2160

Author version available

Microfluidic spinning of micro- and nano-scale fibers for tissue engineering

Y. Jun, E. Kang, S. Chae and S. Lee, Lab Chip, 2014, 14, 2145 DOI: 10.1039/C3LC51414E

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