Issue 6, 2011

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

Abstract

We report the effect of carboxyl functionalization of graphene in pacifying its strong hydrophobic interaction with cells and associated toxic effects. Pristine graphene was found to accumulate on the cell membrane causing high oxidative stress leading to apoptosis, whereas carboxyl functionalized hydrophilic graphene was internalized by the cells without causing any toxicity.

Graphical abstract: Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

Supplementary files

Article information

Article type
Communication
Submitted
14 Febr. 2011
Accepted
15 Apr. 2011
First published
12 Maijs 2011

Nanoscale, 2011,3, 2461-2464

Differential nano-bio interactions and toxicity effects of pristine versus functionalized graphene

A. Sasidharan, L. S. Panchakarla, P. Chandran, D. Menon, S. Nair, C. N. R. Rao and M. Koyakutty, Nanoscale, 2011, 3, 2461 DOI: 10.1039/C1NR10172B

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