Issue 6, 2004

Biosynthesis of pantothenate

Abstract

Covering: 1933–2004

Pantothenate is an essential metabolite for all biological systems, however the biosynthetic pathway is limited to plants, eubacteria and archaea. This suggests that the pathway is a strong candidate for the discovery of novel antibiotic and herbicidal compounds. The enzymology of this short pathway in both bacteria and plants is discussed in detail. In addition a short survey of studies of the whole pathway, and a discussion of both the metabolism and the transport of pantothenate are included.

Graphical abstract: Biosynthesis of pantothenate

Article information

Article type
Review Article
Submitted
15 Sept. 2004
First published
28 Okt. 2004

Nat. Prod. Rep., 2004,21, 695-721

Biosynthesis of pantothenate

M. E. Webb, A. G. Smith and C. Abell, Nat. Prod. Rep., 2004, 21, 695 DOI: 10.1039/B316419P

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