Issue 3, 2023

Divergent synthesis of quinoxalin-2(1H)-one derivatives through photoinduced C–H functionalization without a photocatalyst

Abstract

Herein, we report a visible-light-driven divergent transformation of quinoxalin-2(1H)-ones mediated using H2O2 as a green oxidant. This reaction is controlled by the reaction atmosphere, providing 3-alkylquinoxalin-2(1H)-ones and quinoxaline-2,3(1H,4H)-diones in moderate to excellent yields, respectively. This method shows broad substrate scope, high atom economy and mild conditions.

Graphical abstract: Divergent synthesis of quinoxalin-2(1H)-one derivatives through photoinduced C–H functionalization without a photocatalyst

Supplementary files

Article information

Article type
Research Article
Submitted
27 Sept. 2022
Accepted
10 Dec. 2022
First published
13 Dec. 2022

Org. Chem. Front., 2023,10, 611-623

Divergent synthesis of quinoxalin-2(1H)-one derivatives through photoinduced C–H functionalization without a photocatalyst

C. Liang, Y. Guo, Y. Zhang, Z. Wang, L. Li and W. Li, Org. Chem. Front., 2023, 10, 611 DOI: 10.1039/D2QO01531E

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