Issue 24, 2023

Lanthanide-based luminescent probes for biological magnesium: accessing polyphosphate-bound Mg2+

Abstract

Biomolecule-bound Mg2+ species, particularly polyphosphate complexes, represent a large and dynamic fraction of the total cellular magnesium that is essential for cellular function but remains invisible to most indicators. Here we report a new family of Eu(III)-based indicators, the MagQEu family, functionalized with a 4-oxo-4H-quinolizine-3-carboxylic acid metal recognition group/sensitization antenna for turn-on, luminescence-based detection of biologically relevant Mg2+ species.

Graphical abstract: Lanthanide-based luminescent probes for biological magnesium: accessing polyphosphate-bound Mg2+

Supplementary files

Article information

Article type
Communication
Submitted
31 Dec. 2022
Accepted
27 Febr. 2023
First published
28 Febr. 2023

Chem. Commun., 2023,59, 3586-3589

Author version available

Lanthanide-based luminescent probes for biological magnesium: accessing polyphosphate-bound Mg2+

B. Pinto-Pacheco, Q. Lin, C. W. Yan, S. de Melo Silva and D. Buccella, Chem. Commun., 2023, 59, 3586 DOI: 10.1039/D2CC07095B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements