Issue 3, 2023

A near-infrared GPX4 fluorescent probe for non-small cell lung cancer imaging

Abstract

Glutathione peroxidase 4 (GPX4) is overexpressed in non-small cell lung cancer (H1299) cells. In this work, a near-infrared fluorescent probe ENBO-ML210 was developed. In vitro and in vivo imaging results showed that ENBO-ML210 could target and visualize GPX4 in H1299 cells, exhibiting potential for the diagnosis of non-small lung cancer.

Graphical abstract: A near-infrared GPX4 fluorescent probe for non-small cell lung cancer imaging

Supplementary files

Article information

Article type
Communication
Submitted
14 Nov. 2022
Accepted
01 Dec. 2022
First published
02 Dec. 2022

Chem. Commun., 2023,59, 294-297

A near-infrared GPX4 fluorescent probe for non-small cell lung cancer imaging

Q. Hu, W. Zhu, J. Du, S. Long, W. Sun, J. Fan and X. Peng, Chem. Commun., 2023, 59, 294 DOI: 10.1039/D2CC06161A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements