Issue 27, 2021

A robust CRISPR–Cas12a biosensor coated with metal–organic framework

Abstract

Metal–organic frameworks (MOFs) are proposed to protect a CRISPR-associated enzyme/RNA complex from harsh environments, while the complex can be quickly released from MOFs with high efficiency. Therefore, the application of CRISPR-powered biosensing can be more feasible.

Graphical abstract: A robust CRISPR–Cas12a biosensor coated with metal–organic framework

Supplementary files

Article information

Article type
Communication
Submitted
19 Maijs 2021
Accepted
20 Jūn. 2021
First published
21 Jūn. 2021

J. Mater. Chem. B, 2021,9, 5451-5455

A robust CRISPR–Cas12a biosensor coated with metal–organic framework

L. Sha, Y. Han, M. Wang, S. Wu, J. Yang and G. Li, J. Mater. Chem. B, 2021, 9, 5451 DOI: 10.1039/D1TB01126J

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