Issue 69, 2021

Photoredox B–H functionalization to selective B–N(sp3) coupling of nido-carborane with primary and secondary amines

Abstract

Access to nido-carborane site-selective B–N(sp3) coupling by photoredox catalysed B–H activation has been achieved for the first time, which leads to the synthesis of a series of nitrogen-containing nido-carboranes with moderate to good yields. This protocol is applicable to primary and secondary amines containing alkyl, or heteroaryl groups as well as sulfonamides. Furthermore, the open to air and metal-free conditions with excellent site-selectivity represent a significant improvement for B–H functionalization of nido-carboranes with organic functionalities.

Graphical abstract: Photoredox B–H functionalization to selective B–N(sp3) coupling of nido-carborane with primary and secondary amines

Supplementary files

Article information

Article type
Communication
Submitted
22 Jūn. 2021
Accepted
26 Jūl. 2021
First published
27 Jūl. 2021

Chem. Commun., 2021,57, 8580-8583

Photoredox B–H functionalization to selective B–N(sp3) coupling of nido-carborane with primary and secondary amines

R. Huang, W. Zhao, S. Xu, J. Xu, C. Li, C. Lu and H. Yan, Chem. Commun., 2021, 57, 8580 DOI: 10.1039/D1CC03326C

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements