Issue 70, 2021

Electrochemical reduction of fluoroalkyl sulfones for radical fluoroalkylation of alkenes

Abstract

Radical fluoroalkylation of alkenes has been developed by electrochemical reduction of fluoroalkyl sulfones. A series of electron-deficient alkenes readily undergo hydrofluoroalkylation in good to excellent yields. This chemistry represents the first example of electrochemical generation of fluoroalkyl radicals from sulfones, which are used for practical radical fluoroalkylation of organic compounds.

Graphical abstract: Electrochemical reduction of fluoroalkyl sulfones for radical fluoroalkylation of alkenes

Supplementary files

Article information

Article type
Communication
Submitted
19 Jūn. 2021
Accepted
02 Aug. 2021
First published
02 Aug. 2021

Chem. Commun., 2021,57, 8750-8753

Electrochemical reduction of fluoroalkyl sulfones for radical fluoroalkylation of alkenes

X. Zhou, C. Ni, L. Deng and J. Hu, Chem. Commun., 2021, 57, 8750 DOI: 10.1039/D1CC03258E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements