Issue 5, 2019

Biosynthesis of bioactive natural products from Basidiomycota

Abstract

The Basidiomycota, also called club fungi, comprise a diverse group of fungi. Basidiomycota are strongly related to ecosystem functioning along with human life. These fungi display a wide range of bioactivities, and some are known to produce of deadly toxins or hallucinogens. Some Basidiomycota have be used as medicinal mushrooms for thousands of years. Recently, the biosyntheses of several classes of natural products from Basidiomycota have been reported. Here, we review recent studies on the biosynthetic pathways and enzymes of bioactive natural products from Basidiomycota fungi, with a focus on terpenoids, alkaloids, ribosomally synthesized and post-translationally modified peptides (RiPPs), and polyketides.

Graphical abstract: Biosynthesis of bioactive natural products from Basidiomycota

  • This article is part of the themed collection: Biosynthesis

Article information

Article type
Review Article
Submitted
07 Nov. 2018
Accepted
13 Dec. 2018
First published
14 Dec. 2018

Org. Biomol. Chem., 2019,17, 1027-1036

Biosynthesis of bioactive natural products from Basidiomycota

H. Lin, R. T. Hewage, Y. Lu and Y. Chooi, Org. Biomol. Chem., 2019, 17, 1027 DOI: 10.1039/C8OB02774A

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