Issue 29, 2018

Integrated paper-based microfluidic devices for point-of-care testing

Abstract

As a rapidly developing field, paper-based microfluidic devices (μPADs) are expected to have profound implications, especially for in vitro diagnosis. In particular, integrated μPADs, with the merits of capillary-driven force, cost effectiveness, mass production and ease of use, are emerging as ideal tools for personal diagnosis; sample collection/pretreatment, signal transduction and results output can be simplified into one μPAD with minimal need for complex operation. In this review, we emphasize the latest developments of integrated μPADs and highlight the accomplishments and challenges of each component, including sample collection/pretreatment, signal transduction and amplification, and results output. Moreover, we give an overview of the growing trend of novel integrated μPADs and analyze existing challenges as well as potential directions for integrated μPADs for point-of-care testing (POCT).

Graphical abstract: Integrated paper-based microfluidic devices for point-of-care testing

Article information

Article type
Minireview
Submitted
18 Apr. 2018
Accepted
20 Jūn. 2018
First published
22 Jūn. 2018

Anal. Methods, 2018,10, 3567-3581

Integrated paper-based microfluidic devices for point-of-care testing

T. Tian, Y. Bi, X. Xu, Z. Zhu and C. Yang, Anal. Methods, 2018, 10, 3567 DOI: 10.1039/C8AY00864G

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