Issue 20, 2016

Low molecular weight gels induced differentiation of mesenchymal stem cells

Abstract

Four low molecular weight gels (LMWGs) with different moduli were fabricated as scaffolds to investigate the differentiation of mesenchymal stem cells (MSCs). The MSCs differentiated to osteoblasts in rigid LMWGs and to chondrocytes in soft LMWGs. The critical modulus to induce the different differentiations was between 10 and 20 kPa.

Graphical abstract: Low molecular weight gels induced differentiation of mesenchymal stem cells

  • This article is part of the themed collection: Stem Cells

Supplementary files

Article information

Article type
Communication
Submitted
03 Dec. 2015
Accepted
15 Febr. 2016
First published
16 Febr. 2016

J. Mater. Chem. B, 2016,4, 3504-3508

Author version available

Low molecular weight gels induced differentiation of mesenchymal stem cells

Y. Hu, W. Gao, F. Wu, H. Wu, B. He and J. He, J. Mater. Chem. B, 2016, 4, 3504 DOI: 10.1039/C5TB02546J

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