Issue 40, 2014

Synthesis of squaraine dyes under mild conditions: applications for labelling and sensing of biomolecules

Abstract

We report the synthesis of squaraine dyes under mild conditions by carbodiimide activation of squaric acid or semi-squaraine dyes. Despite low yields when the reaction was carried out in solution, these conditions were successfully applied to efficient peptide labelling on resin and nucleic acid sensing in solution.

Graphical abstract: Synthesis of squaraine dyes under mild conditions: applications for labelling and sensing of biomolecules

Supplementary files

Article information

Article type
Communication
Submitted
14 Okt. 2013
Accepted
17 Dec. 2013
First published
18 Dec. 2013

Chem. Commun., 2014,50, 5288-5290

Synthesis of squaraine dyes under mild conditions: applications for labelling and sensing of biomolecules

M. H. Sleiman and S. Ladame, Chem. Commun., 2014, 50, 5288 DOI: 10.1039/C3CC47894G

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