Issue 39, 2013

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

Abstract

A novel bis(ferrocenyl chalcone) silicon(IV) phthalocyanine has been prepared in which the disulfide linker can be cleaved by dithiothreitol. The separation of the ferrocenyl quencher and the phthalocyanine core greatly enhances the fluorescence emission, singlet oxygen production and in vitro photocytotoxicity.

Graphical abstract: A disulfide-linked conjugate of ferrocenyl chalcone and silicon(iv) phthalocyanine as an activatable photosensitiser

Supplementary files

Article information

Article type
Communication
Submitted
04 Okt. 2012
Accepted
24 Okt. 2012
First published
07 Nov. 2012

Chem. Commun., 2013,49, 4274-4276

A disulfide-linked conjugate of ferrocenyl chalcone and silicon(IV) phthalocyanine as an activatable photosensitiser

J. T. F. Lau, X. Jiang, D. K. P. Ng and P. Lo, Chem. Commun., 2013, 49, 4274 DOI: 10.1039/C2CC37251G

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