Synthetic Reaction Updates is a literature alerting service keeping you up to date with recent developments in synthetic organic chemistry. Covering a wide range of primary sources, Synthetic Reaction Updates includes the most important and exciting reactions published in the recent scientific literature. The updates are presented as easily readable reaction schemes and are also searchable by topic and reaction type. Subscribers can set up personalised searches and receive alerts of the latest developments directly via email. Synthetic Reaction Updates replaced Methods in Organic Synthesis and Catalysts & Catalysed Reactions in 2015.


Synthetic Reaction Updates covers a broad range of primary research published in general chemistry and organic chemistry journals. Our Scientific Editors identify the most interesting, novel and relevant reactions, tailoring the selection of articles with synthetic organic chemists in mind. The range of journals included can be seen in the source list.

Information provided by Synthetic Reaction Updates

Each record in the update provides a redrawn reaction scheme with full bibliographic information for the original article. There are also direct links to the publisher’s website where the article can be downloaded. Bibliographic information can be imported into citation management programmes, and the reaction schemes downloaded. Reactions are also classified by reaction type to allow easy browsing.

Email alerts

Personalised searches can be saved to a user’s profile and used to create automatic email alerts that will send details of recently added reactions without having to perform a new search. Readers can also sign up to weekly or monthly updates to browse when they choose.

Scientific Editors

Our Scientific Editors select the most interesting and useful reactions from the recently published scientific literature to include in Synthetic Reaction Updates.

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Nessa Carson, Syngenta, UK

Nessa Carson was born in Warrington, England. She received her MChem degree from Oxford University, before completing postgraduate studies in catalysis and organic methodology at the University of Illinois at Urbana-Champaign. She started in industry as a synthetic chemist for AMRI, then moved within the company to run the high-throughput automation facility on behalf of Eli Lilly in Windlesham, working across both the discovery and process chemistry arenas. She then worked in process development using automation at Pfizer. Nessa started at Syngenta in 2020, working in synthesis, automation, and data management. She maintains a website of useful chemistry resources.

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Matthew Cook, Montana State University, USA

Matthew Cook received an MChem (Hons) degree from the University of Sheffield in 2001. Following this, he moved to the University of Bristol to conduct his doctoral studies under the tutelage of Prof. Timothy Gallagher and was awarded a Ph.D. in 2005. Postdoctoral appointments were conducted with Prof. Tomislav Rovis at Colorado State University (2005-2008) and Prof. Anthony Barrett at Imperial College London (2008-2009). He began his independent academic career at Queen’s University Belfast as a Lecturer in 2009 before moving to Montana State in 2016 where he is currently an Assistant Professor. His research interests include: (1) The development of novel stereoselective cascade reactions for complex molecule synthesis using Lewis acid, hydrogen-bond donor and transition metal catalysis; and (2) immunology medicinal chemistry.

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David Heard, University of Bristol, UK

David Heard completed an MChem (Hons) degree at the University of Sheffield, before moving to the University of Bristol in 2014 to join the Bristol Chemical Synthesis Centre for Doctoral Training. He completed his Ph.D. under the supervision of Prof. Chris Willis and Prof. Russell Cox (Leibniz University Hannover), studying the structural elucidation and total synthesis of maledride natural products. Since 2019, he has been a postdoctoral researcher with Dr Alastair Lennox at the University of Bristol, where his research focuses on new methods for reaction optimisation.

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Zheng Li, Haihe Biopharma Co., Ltd., P. R. China

Zheng Li obtained her Ph.D. degree in 2010 from Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), under the guidance of Prof. Yuan-Chao Li. She joined Prof. Yoshito Kishi’s lab at Harvard University as a postdoctoral researcher in Jun of 2010. From 2012 to 2014, she worked at the Department of Molecular & Medical Pharmacology, University of California, Los Angeles in Prof. Caius G. Radu’s lab, where she developed several small molecule inhibitors of the nucleoside salvage enzyme deoxycytidine kinase (dCK) as potential cancer therapeutics. In 2015, she joined the Abbvie Shanghai R&D Center until its shutdown. In the beginning of 2016, she joined Prof. Dawei Ma’s group in Shanghai Institute of Organic Chemistry (SIOC), Chinese Academy of Sciences (CAS). She is currently a Senior Manager of the Pre-clinical Research Department at Haihe Biopharma Co., Ltd.

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Lara Malins, Australian National University, Australia

Lara Malins completed her B.A. in chemistry at Boston University in 2009 before relocating to the University of Sydney to undertake her Ph.D. with Prof. Richard Payne on the development of new peptide ligation strategies. In 2015, Lara joined the laboratory of Prof. Phil Baran at the Scripps Research Institute as a National Institutes of Health postdoctoral research fellow. She returned to Australia in November 2017 to begin her independent academic career at the Australian National University, where her group focuses on the development of new synthetic methods for drug discovery, natural product synthesis, and chemical biology.

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Amit Pawar, IIT Mandi, India

Amit B. Pawar completed his M.Sc in organic chemistry from University of Pune in 2007. He obtained his Ph.D. in 2012 from Indian Institute of Science, Bangalore under the supervision of Prof. K. R. Prasad, where he worked in the area of total synthesis of bio-active natural products. He was awarded the “2012 Eli-Lilly and Company Asia Outstanding Thesis Award.” He carried out his post-doctoral work with Prof. Sukbok Chang at KAIST, South Korea in the area of transition metal catalysis (2013-2015). Later on, he worked as a DST-Inspire Faculty at CSIR-IICT, Hyderabad from April 2015 to October 2019. Currently, he is working as an Assistant Professor in the School of Basic Sciences at IIT Mandi, Himachal Pradesh, India. His research is focused on the utilisation of first-row transition metals for C−H functionalisation and development of mild C−H activation reactions.

Source list

  • ACS Catalysis
  • Advanced Synthesis & Catalysis
  • Angewandte Chemie International Edition
  • Applied Organometallic Chemistry
  • Asian Journal of Organic Chemistry
  • Chem
  • ChemCatChem
  • Chemical Communications
  • Chemical Science
  • Chemistry – A European Journal
  • Chemistry – An Asian Journal
  • European Journal of Organic Chemistry
  • Green Chemistry
  • Journal of the American Chemical Society
  • Nature
  • Nature Catalysis
  • Nature Chemistry
  • Organic & Biomolecular Chemistry
  • Organic Chemistry Frontiers
  • Organic Letters
  • Organometallics
  • RSC Advances
  • Science
  • Synlett
  • Synthesis
  • Tetrahedron
  • Tetrahedron Letters
  • The Journal of Organic Chemistry

Contact us

Guy Jones: Executive Editor, Data

Sarah Rogers: Content Editor, Synthetic Reaction Updates

Please feel free to contact the Synthetic Reaction Updates team at with any questions or comments.
Version : 2021.0.21.0
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