Switching the polarity of mouse enteroids affects the epithelial interplay with prenylated phenolics from licorice (Glycyrrhiza) roots

Sarah van Dinteren, Carla Araya-Cloutier, Edyta Robaczewska, Mellody den Otter, Renger Witkamp, Jean-Paul Vincken and Jocelijn Meijerink

Food Funct., 2024, 15, 1852
DOI: 10.1039/D3FO02961A

Pharmacological effects and mechanism of Maxing Shigan decoction in the treatment of Pseudomonas aeruginosa pneumonia

Yingli Xu, Lei Bao, Shan Cao, Bo Pang, Jingsheng Zhang, Yu Zhang, Mengping Chen, Yaxin Wang, Qiyue Sun, Ronghua Zhao, Shanshan Guo, Jing Sun and Xiaolan Cui

Journal of Ethnopharmacology, 2024, 320, 117424
DOI: 10.1016/j.jep.2023.117424

Biological insights and therapeutic potential of Glycyrrhiza uralensis and its bioactive compounds: an updated review

Sibhghatulla Shaikh, Khurshid Ahmad, Jeong Ho Lim, Syed Sayeed Ahmad, Eun Ju Lee and Inho Choi

Arch. Pharm. Res., 2024, 47, 871
DOI: 10.1007/s12272-024-01522-0

Immunomodulation of Glycyrrhiza Polysaccharides In Vivo Based on Microbiome and Metabolomics Approaches

Yixuan Wu, Jie Sun, Wenjie Xie, Simin Xue, Xinli Li, Jianming Guo, Jinjun Shan, Guoping Peng and Yunfeng Zheng

Foods, 2025, 14, 874
DOI: 10.3390/foods14050874

Licochalcone C Inhibits the Growth of Human Colorectal Cancer HCT116 Cells Resistant to Oxaliplatin

Seung-On Lee, Sang Hoon Joo, Jin-Young Lee, Ah-Won Kwak, Ki-Taek Kim, Seung-Sik Cho, Goo Yoon, Yung Hyun Choi, Jin Woo Park and Jung-Hyun Shim

Biomol Ther (Seoul), 2024, 32, 104
DOI: 10.4062/biomolther.2023.167

Licochalcone A inhibits the assembly function of β-barrel assembly machinery in Escherichia coli

Liangwan Wei, Zhe Wang, Yindi Chu, Kun Cai, Wei Li, Piying Huang, Youcai Qin, Dailin Liu, Xiaocui Zhuang, Mingquan Guo, Xinbo Song and Enguo Fan

Biochemical and Biophysical Research Communications, 2023, 668, 90
DOI: 10.1016/j.bbrc.2023.05.083

Mechanistic Insights into the Membrane Permeabilization Activity of Antimicrobial Prenylated Isoflavonoids: A Comparative Study of Glabridin, Wighteone, and Lupiwighteone

Alberto Bombelli, Paolo Calligari, Gianfranco Bocchinfuso, Jean-Paul Vincken, Tjakko Abee, Heidy M.W. den Besten, Lorenzo Stella and Carla Araya-Cloutier

J. Agric. Food Chem., 2025, 73, 6668
DOI: 10.1021/acs.jafc.5c01688

Biotransformation and Epithelial Toxicity of Prenylated Phenolics from Licorice Roots (Glycyrrhiza spp.) in 3D Apical-Out Mucus-Producing Human Enteroids

Sarah van Dinteren, Carla Araya-Cloutier, Shanna Bastiaan-Net, Anouk Boudewijn, Tjarda van Heek, Jean-Paul Vincken, Renger Witkamp and Jocelijn Meijerink

J. Agric. Food Chem., 2024, 72, 20396
DOI: 10.1021/acs.jafc.4c03120

Potential of Glycyrrhiza in the prevention of colitis-associated colon cancer

Fang Liu, Zhili Gu, Feiyang Yi, Xue Liu, Wenxuan Zou, Qingxia Xu, Yun Yuan, Nianzhi Chen and Jianyuan Tang

Fitoterapia, 2025, 181, 106398
DOI: 10.1016/j.fitote.2025.106398

Composition and immunomodulatory activity of an arabinoxylan polysaccharide-rich extract of Agaricus subrufescens fermented rye

Caifang Wen, Paulina Krzysica, Gijs van Erven, Coen H. Smits, Sonja de Vries, Huub F.J. Savelkoul, Hauke Smidt, Edwin Tijhaar and Henk A. Schols

International Journal of Biological Macromolecules, 2025, 318, 144861
DOI: 10.1016/j.ijbiomac.2025.144861

Effects of the antimicrobial glabridin on membrane integrity and stress response activation in Listeria monocytogenes

Alberto Bombelli, Carla Araya-Cloutier, Sjef Boeren, Jean‑Paul Vincken, Tjakko Abee and Heidy M.W. den Besten

Food Research International, 2024, 175, 113687
DOI: 10.1016/j.foodres.2023.113687

Pharmacological potential of natural chalcones: a recent studies and future perspective

Suman Adhikari, Priyatosh Nath, Vishal Kumar Deb, Niranjan Das, Antara Banerjee, Surajit Pathak and Asim K. Duttaroy

Front. Pharmacol., 2025, 16
DOI: 10.3389/fphar.2025.1570385

Prenylated isoflavonoids from Fabaceae against the NorA efflux pump in Staphylococcus aureus

Marina Ika Irianti, Jean-Paul Vincken, Sarah van Dinteren, Ellen ter Beest, Klaas Martinus Pos and Carla Araya-Cloutier

Sci Rep, 2023, 13
DOI: 10.1038/s41598-023-48992-8

New Insights into the Anti-Oomycete Mechanisms of a Leaf Extract from Glycyrrhiza glabra Against Pseudoperonospora cubensis

Franziska M. Porsche, Jeanine Franck and Annegret Schmitt

Phytopathology®, 2024, 114, 348
DOI: 10.1094/PHYTO-01-23-0037-R

Glycyrrhiza uralensis extract improves dexamethasone-induced sarcopenia via regulating myostatin- and FoxO3a-mediated E3 ubiquitin ligase

Yulong Zheng, SoEun An, Ga-Yeon Kim, Ki-Soo Han, Young-Jin Baek and Il-Jun Kang

Food Bioscience, 2024, 62, 105521
DOI: 10.1016/j.fbio.2024.105521

Antimicrobial properties of alternative medicines used in the management of infections in diabetic patients: A comprehensive review

Elizabeth Bosede Aladejana, Olusesan Adeyemi Adelabu, Adebowale Emmanuel Aladejana and Sizwe Innocent Ndlovu

Pharmacological Research - Modern Chinese Medicine, 2024, 11, 100432
DOI: 10.1016/j.prmcm.2024.100432

Restoring Colistin Sensitivity and Combating Biofilm Formation: Synergistic Effects of Colistin and Usnic Acid against Colistin-Resistant Enterobacteriaceae

Yi Zhang, Yijia Han, Zeyu Huang, Yali Huang, Jingchun Kong, Yao Sun, Jianming Cao and Tieli Zhou

ACS Infect. Dis., 2023, 9, 2457
DOI: 10.1021/acsinfecdis.3c00315

Deciphering the Anti-Listerial Activity and Phytochemical Composition of Licorice Root Extract Using LC-MS/MS in Combination with In Vitro and Computational Evaluations

Christodoulos Michael, Atalanti Christou, Ana Gómez-Caravaca, Vlasios Goulas, Catherine Rees and George Botsaris

Applied Sciences, 2025, 15, 5276
DOI: 10.3390/app15105276

Inhibition by components of Glycyrrhiza uralensis of 3CLpro and HCoV-OC43 proliferation

Jang Hoon Kim, Yea-In Park, Mok Hur, Woo Tae Park, Youn-Ho Moon, Yun-Chan Huh, Tae IL Kim, Min Hye Kang, Jong Seong Kang, Chong Woon Cho and Junsoo Park

Journal of Enzyme Inhibition and Medicinal Chemistry, 2023, 38
DOI: 10.1080/14756366.2023.2242704

Licochalcone H Targets EGFR and AKT to Suppress the Growth of Oxaliplatin -Sensitive and -Resistant Colorectal Cancer Cells

Seung-On Lee, Mee-Hyun Lee, Ah-Won Kwak, Jin-Young Lee, Goo Yoon, Sang Hoon Joo, Yung Hyun Choi, Jin Woo Park and Jung-Hyun Shim

Biomol Ther (Seoul), 2023, 31, 661
DOI: 10.4062/biomolther.2023.155

Unraveling the molecular drivers of antibacterial prenylated (iso)flavonoids and chalcones against Streptococcus mutans

Sarah van Dinteren, Janniek Henrieke Ritsema, Mark Gerardus Sanders, Jocelijn Meijerink, Jean-Paul Vincken and Carla Araya-Cloutier

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-98782-7

Exploring the scope of traditional Chinese medicinal plants in battle of antibiotic resistance – A comprehensive review

Sobhanjan Bhunia, Sonia Mallick, Asif Iqbal Mondal, Arkaprava Saha, Priyanka Ray, Sumana Roy and Tamalika Chakraborty

Pharmacological Research - Modern Chinese Medicine, 2025, 14, 100574
DOI: 10.1016/j.prmcm.2025.100574