A human pathophysiological 3D-bone marrow model reveals immune and stromal cell heterogeneity

Mariette Giannini, Giulia Campione, Lea Torcq, Sylvain Donadelli, Maroua Bencheikh, Sophia Bounaud, Sandrine Jeanpierre, Kevin Geistlich, Veronique Maguer-Satta, Sylvain Lefort and Julie Leca

Commun Biol, 2026, 9
DOI: 10.1038/s42003-025-09433-6

Generating human bone marrow organoids for disease modeling and drug discovery

Aude-Anais Olijnik, Antonio Rodriguez-Romera, Zoë C. Wong, Yuqi Shen, Jasmeet S. Reyat, Natalie J. Jooss, Julie Rayes, Bethan Psaila and Abdullah O. Khan

Nat Protoc, 2024, 19, 2117
DOI: 10.1038/s41596-024-00971-7

Complex in vitro models positioned for impact to drug testing in pharma: a review

Serah Kang, Eugene C Chen, Helen Cifuentes, Julia Y Co, Gabrielle Cole, Jessica Graham, Rebecca Hsia, Tomomi Kiyota, Jessica A Klein, Katharina T Kroll, Lenitza M Nieves Lopez, Leah M Norona, Heshan Peiris, Ratnakar Potla, Monica Romero-Lopez, Julien G Roth, Min Tseng, Aaron M Fullerton and Kimberly A Homan

Biofabrication, 2024, 16, 042006
DOI: 10.1088/1758-5090/ad6933

Modeling the effects of radiation on the bone tumor microenvironment: opportunities for exploring combination therapies in microphysiologic systems

Kailey N. Jackett, Devin L. DaPonte, Pranav Soman and Jason A. Horton

Cell Mol Biol Lett, 2025, 30
DOI: 10.1186/s11658-025-00774-y

Modeling immunity in microphysiological systems

Brian J Kwee, Xiaoqing Li, Xinh-Xinh Nguyen, Courtney Campagna, Johnny Lam and Kyung E Sung

Exp Biol Med (Maywood), 2023, 248, 2001
DOI: 10.1177/15353702231215897