Mitochondria-targeted carbon monoxide delivery combined with singlet oxygen production from a single nanoplatform under 808 nm light irradiation for synergistic anticancer therapy

Qi Tang, Hai-Lin Zhang, Yi Wang, Jing Liu, Shi-Ping Yang and Jin-Gang Liu

J. Mater. Chem. B, 2021, 9, 4241
DOI: 10.1039/D1TB00478F

A method to capture the large relativistic and solvent effects on the UV-vis spectra of photo-activated metal complexes

Joel Creutzberg and Erik Donovan Hedegård

Phys. Chem. Chem. Phys., 2023, 25, 6153
DOI: 10.1039/D2CP04937F

Photocleavable core cross-linked polymeric micelles of polypept(o)ides and ruthenium(ii) complexes

Tobias Alexander Bauer, Jonas Eckrich, Nadine Wiesmann, Felix Kuczelinis, Wen Sun, Xiaolong Zeng, Benjamin Weber, Si Wu, Nicolas Hubert Bings, Sebastian Strieth and Matthias Barz

J. Mater. Chem. B, 2021, 9, 8211
DOI: 10.1039/D1TB01336J

Non-mutagenic Ru(ii)–phosphine-based complexes induce mitochondria-mediated apoptosis in breast cancer cells: from 2D to 3D investigations

Marcos V. Palmeira-Mello, Tamara Teixeira, Analu R. Costa, Aline Maria Machado, Rone A. De Grandis, Leticia P. de Oliveira, Carlos A. F. Moraes, João H. de Araujo-Neto, Victor M. Deflon, Adriano D. Andricopulo, Javier Ellena, Heloisa S. Selistre-de-Araújo, Fillipe V. Rocha and Alzir A. Batista

Inorg. Chem. Front., 2025, 12, 4812
DOI: 10.1039/D5QI00546A

Incorporation of 7-dehydrocholesterol into liposomes as a simple, universal and efficient way to enhance anticancer activity by combining PDT and photoactivated chemotherapy

Youchao Wang, Nana Tian, Chao Li, Yuanjun Hou, Xuesong Wang and Qianxiong Zhou

Chem. Commun., 2019, 55, 14081
DOI: 10.1039/C9CC05691B

Cancer phototherapy by CO releasing terpyridine-based Re(i) tricarbonyl complexes via ROS generation and NADH oxidation

Rajesh Kushwaha, Aarti Upadhyay, Sukanta Saha, Ashish Kumar Yadav, Arpan Bera, Arnab Dutta and Samya Banerjee

Dalton Trans., 2024, 53, 13591
DOI: 10.1039/D4DT01309C

Photosubstitution in a trisheteroleptic ruthenium complex inhibits conjunctival melanoma growth in a zebrafish orthotopic xenograft model

Quanchi Chen, Jordi-Amat Cuello-Garibo, Ludovic Bretin, Liyan Zhang, Vadde Ramu, Yasmin Aydar, Yevhen Batsiun, Sharon Bronkhorst, Yurii Husiev, Nataliia Beztsinna, Lanpeng Chen, Xue-Quan Zhou, Claudia Schmidt, Ingo Ott, Martine J. Jager, Albert M. Brouwer, B. Ewa Snaar-Jagalska and Sylvestre Bonnet

Chem. Sci., 2022, 13, 6899
DOI: 10.1039/D2SC01646J

UCNP@BSA@Ru nanoparticles with tumor-specific and NIR-triggered efficient PACT activity in vivo

Chao Zhang, Xusheng Guo, Xuwen Da, Yishan Yao, Haihua Xiao, Xuesong Wang and Qianxiong Zhou

Dalton Trans., 2021, 50, 7715
DOI: 10.1039/D1DT00777G

Small upconversion-ruthenium nanohybrids for cancer theranostics

Anne Nsubuga, Nour Fayad, Federico Pini, Marta M. Natile and Niko Hildebrandt

Nanoscale, 2025, 17, 3809
DOI: 10.1039/D4NR04210G

Kinetically labile ruthenium(ii) complexes of terpyridines and saccharin: effect of substituents on photoactivity, solvation kinetics, and photocytotoxicity

Priyaranjan Kumar, Prerana Singh, Sanjoy Saren, Sandip Pakira, Sri Sivakumar and Ashis K. Patra

Dalton Trans., 2021, 50, 8196
DOI: 10.1039/D1DT00246E

A Ru-anthraquinone dyad with triple functions of PACT, photoredox catalysis and PDT upon red light irradiation

Chao Zhang, Xusheng Guo, Xuwen Da, Zhanhua Wang, Xuesong Wang and Qianxiong Zhou

Dalton Trans., 2021, 50, 10845
DOI: 10.1039/D1DT01088C

Photodynamic therapy photosensitizers and photoactivated chemotherapeutics exhibit distinct bioenergetic profiles to impact ATP metabolism

Richard J. Mitchell, Dmytro Havrylyuk, Austin C. Hachey, David K. Heidary and Edith C. Glazer

Chem. Sci., 2025, 16, 721
DOI: 10.1039/D4SC05393A

Molecular superoxide radical photogeneration in cancer cells by dipyridophenazine iridium(iii) complexes

Vojtech Novohradsky, Gloria Vigueras, Jitka Pracharova, Natalia Cutillas, Christoph Janiak, Hana Kostrhunova, Viktor Brabec, Jose Ruiz and Jana Kasparkova

Inorg. Chem. Front., 2019, 6, 2500
DOI: 10.1039/C9QI00811J

Photo-responsive hydrogels based on a ruthenium complex: synthesis and degradation

Sara Tavakkoli Fard, Boonya Thongrom, Katharina Achazi, Guoxin Ma, Rainer Haag and C. Christoph Tzschucke

Soft Matter, 2024, 20, 1301
DOI: 10.1039/D3SM01232H

Investigating the influence of relativistic effects on absorption spectra for platinum complexes with light-activated activity against cancer cells

Joel Creutzberg and Erik Donovan Hedegård

Phys. Chem. Chem. Phys., 2020, 22, 27013
DOI: 10.1039/D0CP05143H

Metallodrugs are unique: opportunities and challenges of discovery and development

Elizabeth J. Anthony, Elizabeth M. Bolitho, Hannah E. Bridgewater, Oliver W. L. Carter, Jane M. Donnelly, Cinzia Imberti, Edward C. Lant, Frederik Lermyte, Russell J. Needham, Marta Palau, Peter J. Sadler, Huayun Shi, Fang-Xin Wang, Wen-Ying Zhang and Zijin Zhang

Chem. Sci., 2020, 11, 12888
DOI: 10.1039/D0SC04082G

A detailed density functional theory exploration of the photodissociation mechanism of ruthenium complexes for photoactivated chemotherapy

Daniele Belletto, Fortuna Ponte, Gloria Mazzone and Emilia Sicilia

Dalton Trans., 2024, 53, 8243
DOI: 10.1039/D4DT00834K

An anthracene-pendant ruthenium(ii) complex conjugated to a biotin anchor, an essential handle for photo-induced anti-cancer activity

Geângela de Fátima Sousa Oliveira, Florencio Sousa Gouveia, Aryane de Azevedo Pinheiro, Luiz Gonzaga do Nascimento Neto, Mayron Alves de Vasconcelos, Edson Holanda Teixeira, Ana Claudia Silva Gondim, Luiz Gonzaga de França Lopes, Idalina Maria Moreira de Carvalho and Eduardo Henrique Silva Sousa

New J. Chem., 2020, 44, 6610
DOI: 10.1039/D0NJ00209G

Identification of a photoredox-active Pt(IV) complex that induces light-mediated cell death

Jevon W. Marsh, Lina Hacker, Sophie A. Twigger, Jake A. Vickery, Shitong Huang, Claudia Almuzara Romero, Aaron P. Langston, Ismael Diez-Perez, Rebecca A. Musgrave, Ester M. Hammond and Adam C. Sedgwick

Chem. Sci., 2025
DOI: 10.1039/D5SC02879E

Surfing the limits of cyanine photocages one step at a time

Hana Janeková, Sergey Fisher, Tomáš Šolomek and Peter Štacko

Chem. Sci., 2025, 16, 1677
DOI: 10.1039/D4SC07165D

Photocytotoxic kinetically stable ruthenium(ii)-N,N-donor polypyridyl complexes of oxalate with anticancer activity against HepG2 liver cancer cells

Juhi Sayala, Ekta Srivastava, Priyaranjan Kumar, Nitin Shukla, Ashok Kumar and Ashis K. Patra

Dalton Trans., 2024, 53, 4580
DOI: 10.1039/D3DT04058E

Photoresponsive molecular tools for emerging applications of light in medicine

Ilse M. Welleman, Mark W. H. Hoorens, Ben L. Feringa, Hendrikus H. Boersma and Wiktor Szymański

Chem. Sci., 2020, 11, 11672
DOI: 10.1039/D0SC04187D

New relativistic quantum chemical methods for understanding light-induced therapeutics

Erik Donovan Hedegård and Joel Creutzberg

Dalton Trans., 2022, 51, 16055
DOI: 10.1039/D2DT02233H

Photopharmacology and photoresponsive drug delivery

Yuwei Liu, Tianyi Wang and Weiping Wang

Chem. Soc. Rev., 2025, 54, 5792
DOI: 10.1039/D5CS00125K

Recent progress in photosensitizers for overcoming the challenges of photodynamic therapy: from molecular design to application

Xueze Zhao, Jiangping Liu, Jiangli Fan, Hui Chao and Xiaojun Peng

Chem. Soc. Rev., 2021, 50, 4185
DOI: 10.1039/D0CS00173B

Diazido platinum(iv) complexes for photoactivated anticancer chemotherapy

Huayun Shi, Cinzia Imberti and Peter J. Sadler

Inorg. Chem. Front., 2019, 6, 1623
DOI: 10.1039/C9QI00288J

Transition metal compounds as cancer radiosensitizers

Martin R. Gill and Katherine A. Vallis

Chem. Soc. Rev., 2019, 48, 540
DOI: 10.1039/C8CS00641E

Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation

Marta Jakubaszek, Bruno Goud, Stefano Ferrari and Gilles Gasser

Chem. Commun., 2018, 54, 13040
DOI: 10.1039/C8CC05928D

A water-soluble photolabile ruthenium(ii) complex with a terpyridyl-dicarboxylate ligand: photocytotoxicity triggered by structural strain

Pritha Chatterjee, Madhu Verma, Avinash Kumar Sonkar, Abhijit Saha, Ramranjan Mishra, Sri Sivakumar and Ashis K. Patra

Inorg. Chem. Front., 2025
DOI: 10.1039/D5QI01110H

Bis[pyrrolyl Ru(ii)] triads: a new class of photosensitizers for metal–organic photodynamic therapy

Deborah A. Smithen, Susan Monro, Mitch Pinto, John Roque, Roberto M. Diaz-Rodriguez, Huimin Yin, Colin G. Cameron, Alison Thompson and Sherri A. McFarland

Chem. Sci., 2020, 11, 12047
DOI: 10.1039/D0SC04500D

Quaternary Ru(ii) complexes of terpyridines, saccharin and 1,2-azoles: effect of substituents on molecular structure, speciation, photoactivity, and photocytotoxicity

Priyaranjan Kumar, Prerana Singh, Sanjoy Saren, Juhi Sayala, Sri Sivakumar and Ashis K. Patra

Dalton Trans., 2022, 51, 18416
DOI: 10.1039/D2DT02203F

Fluorination on non-photolabile dppz ligands for improving Ru(ii) complex-based photoactivated chemotherapy

Rena Boerhan, Weize Sun, Na Tian, Youchao Wang, Jian Lu, Chao Li, Xuexin Cheng, Xuesong Wang and Qianxiong Zhou

Dalton Trans., 2019, 48, 12177
DOI: 10.1039/C9DT01594A

Visible light-induced cytotoxicity studies on Co(ii) complexes having an anthracene-based curcuminoid ligand

Dhananjay Das, Atrayee Banaspati, Namisha Das, Bidisha Bora, Md Kausar Raza and Tridib K. Goswami

Dalton Trans., 2019, 48, 12933
DOI: 10.1039/C9DT01576K

A Trojan horse approach for enhancing the cellular uptake of a ruthenium nitrosyl complex

Pablo Labra-Vázquez, Erika Rocha, Yue Xiao, Marine Tassé, Carine Duhayon, Norberto Farfán, Rosa Santillan, Laure Gibot, Pascal G. Lacroix and Isabelle Malfant

Dalton Trans., 2023, 52, 18177
DOI: 10.1039/D3DT03480A

A serendipitous crossed aldol reaction in the ligand periphery of a Ru(ii) polypyridyl complex in silica bed: prospects for delivering anticancer agents for photoactivated chemotherapy

Ramranjan Mishra, Pritha Chatterjee, Ray J. Butcher and Ashis K. Patra

Dalton Trans., 2024, 53, 18484
DOI: 10.1039/D4DT02337D

Red light active Pt(iv)–BODIPY prodrug as a mitochondria and endoplasmic reticulum targeted chemo-PDT agent

Arpan Bera, Srishti Gautam, Somarupa Sahoo, Apurba Kumar Pal, Paturu Kondaiah and Akhil R. Chakravarty

RSC Med. Chem., 2022, 13, 1526
DOI: 10.1039/D2MD00225F

Luminescent naphthalimide-tagged ruthenium(ii)–arene complexes: cellular imaging, photocytotoxicity and transferrin binding

Payal Srivastava, Madhu Verma, Anmol Kumar, Priyanka Srivastava, Ramranjan Mishra, Sri Sivakumar and Ashis K. Patra

Dalton Trans., 2021, 50, 3629
DOI: 10.1039/D0DT02967J

Rapid quantification of ruthenium(ii) polypyridyl anti-cancer drugs using a selective ligand dissociation LC-MS/MS method

Stephanie Mehanna, Kikki Bodman-Smith, Costantine F. Daher and Rony S. Khnayzer

Anal. Methods, 2020, 12, 4517
DOI: 10.1039/D0AY01250E

Metallodrugs in cancer nanomedicine

Quim Peña, Alec Wang, Orysia Zaremba, Yang Shi, Hans W. Scheeren, Josbert M. Metselaar, Fabian Kiessling, Roger M. Pallares, Stefan Wuttke and Twan Lammers

Chem. Soc. Rev., 2022, 51, 2544
DOI: 10.1039/D1CS00468A

Breaking the barrier: an osmium photosensitizer with unprecedented hypoxic phototoxicity for real world photodynamic therapy

John A. Roque, Patrick C. Barrett, Houston D. Cole, Liubov M. Lifshits, Ge Shi, Susan Monro, David von Dohlen, Susy Kim, Nino Russo, Gagan Deep, Colin G. Cameron, Marta E. Alberto and Sherri A. McFarland

Chem. Sci., 2020, 11, 9784
DOI: 10.1039/D0SC03008B

GSH resistant, luminescent 2-(pyren-1-yl)-1H-imidazo[4,5-f][1,10]phenanthroline-based Ru(ii)/Ir(iii)/Re(i) complexes for phototoxicity in triple-negative breast cancer cells

Rishav Das and Priyankar Paira

Dalton Trans., 2023, 52, 15365
DOI: 10.1039/D3DT01667F

A glimpse into the developments, potential leads and future perspectives of anticancer cobalt complexes

Azharudin Khursheed, Nuzhat Khursheed, Nusrat Rashid, Waheed Ahmad Khanday, Afzal Hussain, Mohamed F. Alajmi, Samira Amir, Akhtar Hussain Malik, Jahangir Ahmad Rather, Abdul Haleem Wani, Jahangir Ahmad, Iqbal Hussain, Prince Firdous Iqbal and Waseem A. Wani

RSC Med. Chem., 2025, 16, 4003
DOI: 10.1039/D5MD00323G

The design of small-molecule prodrugs and activatable phototherapeutics for cancer therapy

Hai-Hao Han, Han-Min Wang, Paramesh Jangili, Mingle Li, Luling Wu, Yi Zang, Adam C. Sedgwick, Jia Li, Xiao-Peng He, Tony D. James and Jong Seung Kim

Chem. Soc. Rev., 2023, 52, 879
DOI: 10.1039/D2CS00673A

Biotinylated photoactive Pt(iv) anticancer complexes

Huayun Shi, Cinzia Imberti, Huaiyi Huang, Ian Hands-Portman and Peter J. Sadler

Chem. Commun., 2020, 56, 2320
DOI: 10.1039/C9CC07845B

A near-infrared light-activatable Ru(ii)-coumarin photosensitizer active under hypoxic conditions

Enrique Ortega-Forte, Anna Rovira, Marta López-Corrales, Alba Hernández-García, Francisco José Ballester, Eduardo Izquierdo-García, Mireia Jordà-Redondo, Manel Bosch, Santi Nonell, María Dolores Santana, José Ruiz, Vicente Marchán and Gilles Gasser

Chem. Sci., 2023, 14, 7170
DOI: 10.1039/D3SC01844J

Research progress of azido-containing Pt(IV) antitumor compounds

Meilin Mu, Jiuyu Zhan, Xiaohan Dai and Hongwei Gao

European Journal of Medicinal Chemistry, 2022, 227, 113927
DOI: 10.1016/j.ejmech.2021.113927

A Ru(II)‐Based Nanoassembly Exhibiting Theranostic PACT Activity in NIR Region

Youchao Wang, Na Tian, Weize Sun, Boerhan Rena, Xusheng Guo, Yang Feng, Chao Li, Xuesong Wang and Qianxiong Zhou

Part & Part Syst Charact, 2020, 37
DOI: 10.1002/ppsc.202000045

Photochemistry of Heteroleptic 1,4,5,8-Tetraazaphenanthrene- and Bi-1,2,3-triazolyl-Containing Ruthenium(II) Complexes

Rayhaan Z. Boota, Samantha J. O. Hardman, Gage P. Ashton, Craig R. Rice, Paul A. Scattergood and Paul I. P. Elliott

Inorg. Chem., 2021, 60, 15768
DOI: 10.1021/acs.inorgchem.1c02441

Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

Eszter Kozma, Márton Bojtár and Péter Kele

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202303198

The anti-cancer effect of series of strained photoactivatable Ru(II) polypyridyl complexes on non-small-cell lung cancer and triple negative breast cancer cells

Christelle Fayad, Hassib Audi, Rony S. Khnayzer and Costantine F. Daher

J Biol Inorg Chem, 2021, 26, 43
DOI: 10.1007/s00775-020-01835-7

Critical discussion of the applications of metal complexes for 2-photon photodynamic therapy

Johannes Karges, Hui Chao and Gilles Gasser

J Biol Inorg Chem, 2020, 25, 1035
DOI: 10.1007/s00775-020-01829-5

Alkylgold(III) Complexes Undergo Unprecedented Photo‐Induced β‐Hydride Elimination and Reduction for Targeted Cancer Therapy

Jia Jiang, Bei Cao, Yuting Chen, Hejiang Luo, Jiaying Xue, Xiaolin Xiong and Taotao Zou

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202201103

Recent Advances in Metal Complexes for Antimicrobial Photodynamic Therapy

Thomas W. Rees, Po‐Yu Ho and Jeannine Hess

ChemBioChem, 2023, 24
DOI: 10.1002/cbic.202200796

Drug-free phototherapy of superficial tumors: White light at the end of the tunnel

Stephanie Mehanna, Najwa Mansour, Costantine F. Daher, Maria George Elias, Carole Dagher and Rony S. Khnayzer

Journal of Photochemistry and Photobiology B: Biology, 2021, 224, 112324
DOI: 10.1016/j.jphotobiol.2021.112324

Sonoinduced Tumor Therapy and Metastasis Inhibition by a Ruthenium Complex with Dual Action: Superoxide Anion Sensitization and Ligand Fracture

Maomao He, Zhiyuan Ma, Linhao Zhang, Zhiyu Zhao, Zongwei Zhang, Wenkai Liu, Ran Wang, Jiangli Fan, Xiaojun Peng and Wen Sun

J. Am. Chem. Soc., 2024, 146, 25764
DOI: 10.1021/jacs.4c08278

Riboflavin-Promoted In Situ Photoactivation of Dihydroalkaloid Prodrugs for Cancer Therapy

Xin Yang, Limin Ma, Hongwei Shao, Zikai Zhou, Xia Ling, Mengyu Yao, Guowen Luo, Stefano Scoditti, Emilia Sicilia, Gloria Mazzone, Meng Gao and Ben Zhong Tang

J. Med. Chem., 2022, 65, 15738
DOI: 10.1021/acs.jmedchem.2c01262

Abraham Patchornik: The Contemporary Relevance of His Work for Chemistry and Biology

Kenneth A. Jacobson and Graham C. R. Ellis-Davies

JACS Au, 2025, 5, 3
DOI: 10.1021/jacsau.4c00779

Interaction of the Large Host Q[10] with Metal Polypyridyl Complexes: Binding Modes and Effects on Luminescence

K. M. Anis-Ul-Haque, Clifford E. Woodward, Anthony I. Day and Lynne Wallace

Inorg. Chem., 2020, 59, 3942
DOI: 10.1021/acs.inorgchem.9b03603

Cytotoxicity, cellular localization and photophysical properties of Re(I) tricarbonyl complexes bound to cysteine and its derivatives

Miles S. Capper, Alejandra Enriquez Garcia, Nicolas Macia, Barry Lai, Jian-Bin Lin, Masaharu Nomura, Amir Alihosseinzadeh, Sathish Ponnurangam, Belinda Heyne, Carrie S. Shemanko and Farideh Jalilehvand

J Biol Inorg Chem, 2020, 25, 759
DOI: 10.1007/s00775-020-01798-9

Reconfigurable Surfaces Based on Photocontrolled Dynamic Bonds

Jiahui Liu, Hans‐Jürgen Butt and Si Wu

Adv Funct Materials, 2020, 30
DOI: 10.1002/adfm.201907605

Materials and device design for advanced phototherapy systems

Ju Seung Lee, Jiwon Kim, Yeong-sinn Ye and Tae-il Kim

Advanced Drug Delivery Reviews, 2022, 186, 114339
DOI: 10.1016/j.addr.2022.114339

Organogold(III) Complexes Display Conditional Photoactivities: Evolving From Photodynamic into Photoactivated Chemotherapy in Response to O2Consumption for Robust Cancer Therapy

Yunli Luo, Bei Cao, Mingjie Zhong, Moyi Liu, Xiaolin Xiong and Taotao Zou

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202212689

Synthesis and Structural Characterization of a Glycoconjugated Re(CO)3+ Complex and Its Tendency for CO Release

Bita Abdolahi Sanati, Tran Si Bui Trung, Demi Bonnaventure, Amani M. Ebrahim, Arvi Rauk and Farideh Jalilehvand

Inorg. Chem., 2025, 64, 16347
DOI: 10.1021/acs.inorgchem.5c01648

Photoresponsive metallopolymer nanoparticles for cancer theranostics

Maomao He, Fangman Chen, Dan Shao, Philipp Weis, Zhiyong Wei and Wen Sun

Biomaterials, 2021, 275, 120915
DOI: 10.1016/j.biomaterials.2021.120915

Comparative Study of Sonodynamic and Photoactivated Cancer Therapies with Re(I)-Tricarbonyl Complexes Comprising Phenanthroline Ligands

Rajesh Kushwaha, Virendra Singh, Silda Peters, Ashish Kumar Yadav, Tumpa Sadhukhan, Biplob Koch and Samya Banerjee

J. Med. Chem., 2024, 67, 6537
DOI: 10.1021/acs.jmedchem.3c02485

Photoactivation of Boronic Acid Prodrugs via a Phenyl Radical Mechanism: Iridium(III) Anticancer Complex as an Example

Moyi Liu, Yunli Luo, Junyu Yan, Xiaolin Xiong, Xiwen Xing, Jong Seung Kim and Taotao Zou

J. Am. Chem. Soc., 2023, 145, 10082
DOI: 10.1021/jacs.3c00254

Synthesis and biological assessment of a ruthenium(II) cyclopentadienyl complex in breast cancer cells and on the development of zebrafish embryos

Golara Golbaghi, Irène Pitard, Matthieu Lucas, Mohammad Mehdi Haghdoost, Yossef López de los Santos, Nicolas Doucet, Shunmoogum A. Patten, J. Thomas Sanderson and Annie Castonguay

European Journal of Medicinal Chemistry, 2020, 188, 112030
DOI: 10.1016/j.ejmech.2019.112030

Polymeric Encapsulation of Novel Homoleptic Bis(dipyrrinato) Zinc(II) Complexes with Long Lifetimes for Applications as Photodynamic Therapy Photosensitisers

Johannes Karges, Uttara Basu, Olivier Blacque, Hui Chao and Gilles Gasser

Angewandte Chemie, 2019, 131, 14472
DOI: 10.1002/ange.201907856

Rationally Designed Long-Wavelength Absorbing Ru(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy

Johannes Karges, Franz Heinemann, Marta Jakubaszek, Federica Maschietto, Chloé Subecz, Mazzarine Dotou, Robin Vinck, Olivier Blacque, Mickaël Tharaud, Bruno Goud, Emilio Viñuelas Zahı́nos, Bernhard Spingler, Ilaria Ciofini and Gilles Gasser

J. Am. Chem. Soc., 2020, 142, 6578
DOI: 10.1021/jacs.9b13620

Alkylgold(III) Complexes Undergo Unprecedented Photo‐Induced β‐Hydride Elimination and Reduction for Targeted Cancer Therapy

Jia Jiang, Bei Cao, Yuting Chen, Hejiang Luo, Jiaying Xue, Xiaolin Xiong and Taotao Zou

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202201103

Light Activated Release of Nitrile Ligands from trans-Ru(L)(PPh3)2(nitrile) Complexes

Ross J. Davidson, Yu-Ting Hsu, Dmitry S. Yufit and Andrew Beeby

ACS Omega, 2024, 9, 34098
DOI: 10.1021/acsomega.4c04917

Intracellular Photocatalytic NADH/NAD(P)H Oxidation for Cancer Drug Development

Ashish Kumar Yadav, Rajesh Kushwaha, Arif Ali Mandal, Apurba Mandal and Samya Banerjee

J. Am. Chem. Soc., 2025, 147, 7161
DOI: 10.1021/jacs.4c18328

In Situ Bioconjugation of a Maleimide-Functionalized Ruthenium-Based Photosensitizer to Albumin for Photodynamic Therapy

Robin Vinck, Orsolya Dömötör, Johannes Karges, Marta Jakubaszek, Johanne Seguin, Mickaël Tharaud, Vincent Guérineau, Kevin Cariou, Nathalie Mignet, Éva A. Enyedy and Gilles Gasser

Inorg. Chem., 2023, 62, 15510
DOI: 10.1021/acs.inorgchem.3c01984

Evaluation of photochemotherapeutic potential of a few oxo-bridged dimeric Fe(III) compounds having Salen-type ligands

Dhananjay Das, Md Kausar Raza and Tridib K. Goswami

Polyhedron, 2020, 186, 114614
DOI: 10.1016/j.poly.2020.114614

Investigation of photo-activation on ruthenium(II)–arene complexes for the discovery of potential selective cytotoxic agents

Uttara Basu, Johannes Karges, Florian Chotard, Cédric Balan, Pierre Le Gendre, Gilles Gasser, Ewen Bodio and Raluca Malacea Kabbara

Polyhedron, 2019, 172, 22
DOI: 10.1016/j.poly.2019.02.041

Monofunctional Platinum(II) Anticancer Agents

Suxing Jin, Yan Guo, Zijian Guo and Xiaoyong Wang

Pharmaceuticals, 2021, 14, 133
DOI: 10.3390/ph14020133

Ruthenium(II) Polypyridyl-Based Photocages for an Anticancer Phytochemical Diallyl Sulfide: Comparative Dark and Photoreactivity Studies of Caged and Precursor Uncaged Complexes

Ramranjan Mishra, Abhijit Saha, Pritha Chatterjee, Atish Bhattacharyya and Ashis K. Patra

Inorg. Chem., 2023, 62, 18839
DOI: 10.1021/acs.inorgchem.3c02038

796 nm Activation of a Photocleavable Ruthenium(II) Complex Conjugated to an Upconverting Nanoparticle through Two Phosphonate Groups

Michael S. Meijer, Marta M. Natile and Sylvestre Bonnet

Inorg. Chem., 2020, 59, 14807
DOI: 10.1021/acs.inorgchem.0c00043

Prediction of Pt, Ir, Ru, and Rh complexes light absorption in the therapeutic window for phototherapy using machine learning

V. Vigna, T. F. G. G. Cova, A. A. C. C. Pais and E. Sicilia

J Cheminform, 2025, 17
DOI: 10.1186/s13321-024-00939-5

Assessment of Photoreleasable Linkers and Light-Capturing Antennas on a Photoresponsive Cobalamin Scaffold

Joshua G. Welfare, Michael J. Mortelliti, Caylie A. McGlade, Timothy W. Hartman, Jillian L. Dempsey and David S. Lawrence

J. Org. Chem., 2022, 87, 5076
DOI: 10.1021/acs.joc.1c02931

Primary processes in photophysics and photochemistry of a potential light-activated anti-cancer dirhodium complex

Veronica V. Semionova, Ivan P. Pozdnyakov, Vjacheslav P. Grivin, Ilia V. Eltsov, Danila B. Vasilchenko, Evgeniya V. Polyakova, Alexei A. Melnikov, Sergei V. Chekalin, Lei Wang and Evgeni M. Glebov

Photochem Photobiol Sci, 2024, 23, 153
DOI: 10.1007/s43630-023-00509-y

Diastereoselective Synthesis and Two-Step Photocleavage of Ruthenium Polypyridyl Complexes Bearing a Bis(thioether) Ligand

Michael S. Meijer and Sylvestre Bonnet

Inorg. Chem., 2019, 58, 11689
DOI: 10.1021/acs.inorgchem.9b01669

Synthesis and Photobiology Evaluation of Ru(Ii) Complexes with Expanded Chelate Polypyridyl Ligands

Edith Glazer, Raphael T. Ryan, Kimberly Stevens, Sean Parkin, Richard Mitchell, Austin C. Hachey, John P. Selegue and David K. Heidary

SSRN Journal, 2022
DOI: 10.2139/ssrn.4193386

A Lock‐and‐Kill Anticancer Photoactivated Chemotherapy Agent†

Erik Pieter van Geest, Sina Katharina Götzfried, David M. Klein, Nadiya Salitra, Sorraya Popal, Yurii Husiev, Corjan J. Van der Griend, Xuequan Zhou, Maxime A. Siegler, Gregory F. Schneider and Sylvestre Bonnet

Photochem & Photobiology, 2023, 99, 777
DOI: 10.1111/php.13738

Near infrared light‐induced disassembly of polymeric micelles based on methylene blue conjugated polyethylene glycol

Huy Minh Dao, Amit Raviraj Pillai, Rishi Thakkar, Sanjiv Parajuli, Esteban Urena‐Benavides and Seongbong Jo

J of Applied Polymer Sci, 2021, 138
DOI: 10.1002/app.49665

Conditionally Activatable Visible-Light Photocages

Márton Bojtár, Krisztina Németh, Farkas Domahidy, Gergely Knorr, András Verkman, Mihály Kállay and Péter Kele

J. Am. Chem. Soc., 2020, 142, 15164
DOI: 10.1021/jacs.0c07508

New Designs for Phototherapeutic Transition Metal Complexes

Cinzia Imberti, Pingyu Zhang, Huaiyi Huang and Peter J. Sadler

Angew Chem Int Ed, 2020, 59, 61
DOI: 10.1002/anie.201905171

Ruthenium(II) Polypyridyl Complexes and Metronidazole Derivatives: A Powerful Combination in the Design of Photoresponsive Antibacterial Agents Effective under Hypoxic Conditions

Gina Elena Giacomazzo, Luca Conti, Camilla Fagorzi, Marco Pagliai, Claudia Andreini, Annalisa Guerri, Brunella Perito, Alessio Mengoni, Barbara Valtancoli and Claudia Giorgi

Inorg. Chem., 2023, 62, 7716
DOI: 10.1021/acs.inorgchem.3c00214

Theoretical Study of the Full Photosolvolysis Mechanism of [Ru(bpy)3]2+: Providing a General Mechanistic Roadmap for the Photochemistry of [Ru(N^N)3]2+-Type Complexes toward Both Cis and Trans Photoproducts

Adrien Soupart, Fabienne Alary, Jean-Louis Heully, Paul I. P. Elliott and Isabelle M. Dixon

Inorg. Chem., 2020, 59, 14679
DOI: 10.1021/acs.inorgchem.0c01843

Photochemistry of cis-[Ru(bpy)2(NH3)2]2+ complex, a promising light-activated anticancer agent

A. A. Kokorenko, V. P. Grivin, I. P. Pozdnyakov, A. V. Mikheylis, Yu. A. Belikov, A. A. Melnikov, S. V. Chekalin, D. B. Vasilchenko and E. M. Glebov

Russ Chem Bull, 2025, 74, 933
DOI: 10.1007/s11172-025-4588-4

Self-Assembly of Erlotinib-Platinum(II) Complexes for Epidermal Growth Factor Receptor-Targeted Photodynamic Therapy

Haobing Wang, Yidan Lai, Dan Li, Johannes Karges, Pingyu Zhang and Huaiyi Huang

J. Med. Chem., 2024, 67, 1336
DOI: 10.1021/acs.jmedchem.3c01889

Taking phototherapeutics from concept to clinical launch

Brianna M. Vickerman, Emilia M. Zywot, Teresa K. Tarrant and David S. Lawrence

Nat Rev Chem, 2021, 5, 816
DOI: 10.1038/s41570-021-00326-w

Theranostic imaging and multimodal photodynamic therapy and immunotherapy using the mTOR signaling pathway

Huiling Zhou, Dongsheng Tang, Yingjie Yu, Lingpu Zhang, Bin Wang, Johannes Karges and Haihua Xiao

Nat Commun, 2023, 14
DOI: 10.1038/s41467-023-40826-5

Crystal structure, DNA crosslinking and photo-induced cytotoxicity of oxovanadium(IV) conjugates of boron-dipyrromethene

Arun Kumar, Akanksha Dixit, Somarupa Sahoo, Samya Banerjee, Arnab Bhattacharyya, Aditya Garai, Anjali A. Karande and Akhil R. Chakravarty

Journal of Inorganic Biochemistry, 2020, 202, 110817
DOI: 10.1016/j.jinorgbio.2019.110817

Photochemistry of Ru(II) Triazole Complexes with 6-Membered Chelate Ligands: Detection and Reactivity of Ligand-Loss Intermediates

Katie Eastham, Aaron D. W. Kennedy, Synøve Ø. Scottwell, Jack E. Bramham, Samantha Hardman, Alexander P. Golovanov, Paul A. Scattergood, James D. Crowley and Paul I. P. Elliott

Inorg. Chem., 2024, 63, 9084
DOI: 10.1021/acs.inorgchem.4c00251

Synthesis, Characterization, and Biological Evaluation of the Polymeric Encapsulation of a Ruthenium(II) Polypyridine Complex with Pluronic F‐127/Poloxamer‐407 for Photodynamic Therapy Applications

Johannes Karges, Hui Chao and Gilles Gasser

Eur J Inorg Chem, 2020, 2020, 3242
DOI: 10.1002/ejic.202000545

Maloplatin-B, a Cisplatin-Based BODIPY-Tagged Mito-Specific “Chemo-PDT” Agent Active in Red Light

Vanitha Ramu, Paramita Kundu, Paturu Kondaiah and Akhil R. Chakravarty

Inorg. Chem., 2021, 60, 6410
DOI: 10.1021/acs.inorgchem.1c00124

Cyclic Ruthenium-Peptide Conjugates as Integrin-Targeting Phototherapeutic Prodrugs for the Treatment of Brain Tumors

Liyan Zhang, Peiyuan Wang, Xue-Quan Zhou, Ludovic Bretin, Xiaolong Zeng, Yurii Husiev, Ehider A. Polanco, Gangyin Zhao, Lukas S. Wijaya, Tarita Biver, Sylvia E. Le Dévédec, Wen Sun and Sylvestre Bonnet

J. Am. Chem. Soc., 2023, 145, 14963
DOI: 10.1021/jacs.3c04855

State of the art in organometallic ruthenium metallodrugs for breast cancer treatment: Advances and innovations

Elena Domínguez-Jurado, Agustín Lara-Sánchez, Iván Bravo, Alberto Ocaña and Carlos Alonso-Moreno

Coordination Chemistry Reviews, 2025, 523, 216252
DOI: 10.1016/j.ccr.2024.216252

Not All 3MC States Are the Same: The Role of 3MCcis States in the Photochemical N∧N Ligand Release from [Ru(bpy)2(N∧N)]2+ Complexes

Katie Eastham, Paul A. Scattergood, Danny Chu, Rayhaan Z. Boota, Adrien Soupart, Fabienne Alary, Isabelle M. Dixon, Craig R. Rice, Samantha J. O. Hardman and Paul I. P. Elliott

Inorg. Chem., 2022, 61, 19907
DOI: 10.1021/acs.inorgchem.2c03146

Computational Analysis of Photophysical Properties and Reactivity of a New Phototherapeutic Cyclometalated Au(III)‐Hydride Complex

Stefano Scoditti, Gloria Mazzone and Emilia Sicilia

Chemistry A European J, 2021, 27, 15528
DOI: 10.1002/chem.202102701

Tuning the competition between photoisomerization and photothermy in biomimetic cyclocurcumin analogues

Jérémy Pecourneau, Raúl Losantos, Axel Gansmuller, Stéphane Parant, Yann Bernhard, Maxime Mourer, Antonio Monari and Andreea Pasc

Journal of Photochemistry and Photobiology A: Chemistry, 2023, 439, 114583
DOI: 10.1016/j.jphotochem.2023.114583

Photoactivatable Cell-Selective Dinuclear trans-Diazidoplatinum(IV) Anticancer Prodrugs

Huayun Shi, Isolda Romero-Canelón, Monika Hreusova, Olga Novakova, V. Venkatesh, Abraha Habtemariam, Guy J. Clarkson, Ji-inn Song, Viktor Brabec and Peter J. Sadler

Inorg. Chem., 2018, 57, 14409
DOI: 10.1021/acs.inorgchem.8b02599

A review of important heavy metals toxicity with special emphasis on nephrotoxicity and its management in cattle

Ifrah Tahir and Khalid Ali Alkheraije

Front. Vet. Sci., 2023, 10
DOI: 10.3389/fvets.2023.1149720

Tuning excited state of bipyridyl platinum(II) complexes with bio-active flavonolate ligand: Structures, photoreactivity, and DFT calculations

Xiaozhen Han, Mehdi Sahihi, Sarah Whitfield and Ivan Jimenez

Inorganica Chimica Acta, 2020, 513, 119952
DOI: 10.1016/j.ica.2020.119952

Synthesis, Characterisation and Biological Evaluation of π-Extended Fe(II) Bipyridine Complexes as Potential Photosensitizers for Photodynamic Therapy

Johannes Karges and Gilles Gasser

Inorganica Chimica Acta, 2020, 499, 119196
DOI: 10.1016/j.ica.2019.119196

Prediction and Rationalization of Different Photochemical Behaviors of mer- and fac-Isomers of [Ru(pyridyltriazole)3]2+

Paul A. Scattergood and Paul I. P. Elliott

Inorg. Chem., 2024, 63, 17287
DOI: 10.1021/acs.inorgchem.4c03154

Targeted Cancer Therapy Using Compounds Activated by Light

Petra Dunkel and Janez Ilaš

Cancers, 2021, 13, 3237
DOI: 10.3390/cancers13133237

Metalloimmunotherapy with Rhodium and Ruthenium Complexes: Targeting Tumor‐Associated Macrophages

Nicholas Toupin, Mackenzie K. Herroon, Randolph P. Thummel, Claudia Turro, Izabela Podgorski, Heather Gibson and Jeremy J. Kodanko

Chemistry A European J, 2022, 28
DOI: 10.1002/chem.202104430

Stimuli‐Responsive Metal Complexes for Biomedical Applications

Ivanna Amarsy, Sébastien Papot and Gilles Gasser

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202205900

A New Photoactivatable Ruthenium(II) Complex with an Asymmetric Bis-Thiocarbohydrazone: Chemical and Biological Investigations

Marianna Pioli, Nicolò Orsoni, Mirco Scaccaglia, Rossella Alinovi, Silvana Pinelli, Giorgio Pelosi and Franco Bisceglie

Molecules, 2021, 26, 939
DOI: 10.3390/molecules26040939

Ruthenium (II) polypyridyl complexes as two-photon absorbers and sensitizers: Design, structure-properties relationships and applications

Jean-Luc Fillaut

Coordination Chemistry Reviews, 2024, 518, 216050
DOI: 10.1016/j.ccr.2024.216050

Platinum(IV)-based prodrugs as an alternative to Pt(II)-based drugs: synthesis and biological action

D. V. Spector, A. A. Bubley, E. K. Beloglazkina and O. O. Krasnovskaya

RUSS CHEM REV, 2023, 92, RCR5096
DOI: 10.59761/RCR5096

Low‐Intensity Light‐Responsive Anticancer Activity of Platinum(II) Complex Nanocolloids on 2D and 3D In Vitro Cancer Cell Model

Viviana Vergaro, Francesca Baldassarre, Federica De Castro, Danilo Migoni, Maria Michela Dell’Anna, Piero Mastrorilli, Francesco Paolo Fanizzi, Giuseppe Ciccarella and Domenico Osella

Bioinorganic Chemistry and Applications, 2022, 2022
DOI: 10.1155/2022/9571217

Increasing Anticancer Activity with Phosphine Ligation in Zwitterionic Half-Sandwich Iridium(III), Rhodium(III), and Ruthenium(II) Complexes

Xueyan Hu, Lihua Guo, Mengqi Liu, Qiuya Zhang, Yuwen Gong, Mengru Sun, Shenghan Feng, Youzhi Xu, Yiming Liu and Zhe Liu

Inorg. Chem., 2022, 61, 20008
DOI: 10.1021/acs.inorgchem.2c03279

Red Light‐Responsive Upconverting Nanoparticles for Quantitative and Controlled Release of a Coumarin‐Based Prodrug

Anaïs Brion, Juliane Chaud, Jérémie Léonard, Frédéric Bolze, Stefan Chassaing, Benoît Frisch, Béatrice Heurtault, Antoine Kichler and Alexandre Specht

Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202201474

Green Light-Triggered Photocatalytic Anticancer Activity of Terpyridine-Based Ru(II) Photocatalysts

Arif Ali Mandal, Virendra Singh, Sukanta Saha, Silda Peters, Tumpa Sadhukhan, Rajesh Kushwaha, Ashish Kumar Yadav, Apurba Mandal, Aarti Upadhyay, Arpan Bera, Arnab Dutta, Biplob Koch and Samya Banerjee

Inorg. Chem., 2024, 63, 7493
DOI: 10.1021/acs.inorgchem.4c00650

Triplet‐Triplet Annihilation Upconversion‐Based Photolysis: Applications in Photopharmacology

Maxime Klimezak, Juliane Chaud, Anaïs Brion, Frédéric Bolze, Benoit Frisch, Béatrice Heurtault, Antoine Kichler and Alexandre Specht

Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202400354

Bioorthogonally Assisted Phototherapy: Recent Advances and Prospects

Eszter Kozma, Márton Bojtár and Péter Kele

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202303198

Nature-Inspired Photocatalytic Azo Bond Cleavage with Red Light

Zijian Zhao, Jili Li, Wei Yuan, Dajiao Cheng, Suze Ma, Ye-Fei Li, Zhang-Jie Shi and Ke Hu

J. Am. Chem. Soc., 2024, 146, 1364
DOI: 10.1021/jacs.3c09837

Red light-activable biotinylated copper(II) complex-functionalized gold nanocomposite (Biotin-Cu@AuNP) towards targeted photodynamic therapy

Dulal Musib, Aarti Upadhyay, Maynak Pal, Md Kausar Raza, Indranil Saha, Amit Kunwar and Mithun Roy

Journal of Inorganic Biochemistry, 2023, 243, 112183
DOI: 10.1016/j.jinorgbio.2023.112183

Transition metal complexes as photosensitizers for integrated cancer theranostic applications

Juanjuan Li and Tianfeng Chen

Coordination Chemistry Reviews, 2020, 418, 213355
DOI: 10.1016/j.ccr.2020.213355

Advances in the Development of Prodrugs as Selective Modulators of Estrogen Receptors

Julie A Pollock and Hannah K Parker

Journal of the Endocrine Society, 2022, 6
DOI: 10.1210/jendso/bvac158

Advances in the Phototriggered Synthesis of Single-Chain Polymer Nanoparticles

Ester Verde-Sesto, Agustín Blázquez-Martín and José A. Pomposo

Polymers, 2019, 11, 1903
DOI: 10.3390/polym11111903

Turning Red without Feeling Embarrassed─Xanthenium-Based Photocages for Red-Light-Activated Phototherapeutics

Alexandra Egyed, Krisztina Németh, Tibor Á. Molnár, Mihály Kállay, Péter Kele and Márton Bojtár

J. Am. Chem. Soc., 2023, 145, 4026
DOI: 10.1021/jacs.2c11499

Near-infrared activation of upconversion platforms for non-redox-dependent release of Pt(II)

Marc-Ricard Batten, Josep Antoni Gutiérrez-Orgaz, Fernando Eduardo Maturi, Luís Dias Carlos, Helena Oliveira, Jordi Hernando, Fernando Novio, Antonio Rodríguez-Diéguez, Mercè Capdevila, Òscar Palacios and Pau Bayón

Journal of Inorganic Biochemistry, 2025, 271, 112982
DOI: 10.1016/j.jinorgbio.2025.112982

Advanced strategies in the design of Ir(III) biscyclometalated complexes for PDT

Juan Sanz-Villafruela, Arancha Carbayo, Marta Martínez-Alonso and Gustavo Espino

Coordination Chemistry Reviews, 2025, 534, 216572
DOI: 10.1016/j.ccr.2025.216572

Anticancer Agent with Inexplicable Potency in Extreme Hypoxia: Characterizing a Light-Triggered Ruthenium Ubertoxin

Houston D. Cole, John A. Roque, Ge Shi, Liubov M. Lifshits, Elamparuthi Ramasamy, Patrick C. Barrett, Rachel O. Hodges, Colin G. Cameron and Sherri A. McFarland

J. Am. Chem. Soc., 2022, 144, 9543
DOI: 10.1021/jacs.1c09010

Advancements in platinum-based anticancer drug development: A comprehensive review of strategies, discoveries, and future perspectives

Debsankar Sahoo, Priya Deb, Tamal Basu, Srishti Bardhan, Sayan Patra and Pradip K. Sukul

Bioorganic & Medicinal Chemistry, 2024, 112, 117894
DOI: 10.1016/j.bmc.2024.117894

Nitroimidazole-Based Ruthenium(II) Complexes: Playing with Structural Parameters to Design Photostable and Light-Responsive Antibacterial Agents

Gina Elena Giacomazzo, Luca Conti, Annalisa Guerri, Marco Pagliai, Camilla Fagorzi, Patrick Severin Sfragano, Ilaria Palchetti, Giangaetano Pietraperzia, Alessio Mengoni, Barbara Valtancoli and Claudia Giorgi

Inorg. Chem., 2022, 61, 6689
DOI: 10.1021/acs.inorgchem.1c03032

Synthesis and photobiological evaluation of Ru(II) complexes with expanded chelate polypyridyl ligands

Raphael T. Ryan, Austin C. Hachey, Kimberly Stevens, Sean R. Parkin, Richard J. Mitchell, John P. Selegue, David K. Heidary and Edith C. Glazer

Journal of Inorganic Biochemistry, 2023, 238, 112031
DOI: 10.1016/j.jinorgbio.2022.112031

Structurally Simple Osmium(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy in the Near Infrared**

Asma Mani, Tao Feng, Albert Gandioso, Robin Vinck, Anna Notaro, Lisa Gourdon, Pierre Burckel, Bruno Saubaméa, Olivier Blacque, Kevin Cariou, Jamel‐Eddine Belgaied, Hui Chao and Gilles Gasser

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202218347

Miniature wireless LED-device for photodynamic-induced cell pyroptosis

Sunghoon Rho, Hailey S. Sanders, Bradley D. Smith and Thomas D. O'Sullivan

Photodiagnosis and Photodynamic Therapy, 2024, 47, 104209
DOI: 10.1016/j.pdpdt.2024.104209

Nucleus targeting anthraquinone-based copper (II) complexes as the potent PDT agents: Synthesis, photo-physical and theoretical evaluation

Longjam Reena Devi, Md Kausar Raza, Dulal Musib, Vanitha Ramu, Joshila Devi and Mithun Roy

Inorganica Chimica Acta, 2020, 500, 119208
DOI: 10.1016/j.ica.2019.119208

Density functional study of trans,trans,trans-[Pt(N3)2(OH)2(Py)2] on molecular structure and vibrational spectroscopy

Meilin Mu and Hongwei Gao

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2021, 261, 120022
DOI: 10.1016/j.saa.2021.120022

NIR-Light-Driven Generation of Reactive Oxygen Species Using Ru(II)-Decorated Lipid-Encapsulated Upconverting Nanoparticles

Michael S. Meijer, Victorio Saez Talens, Michiel F. Hilbers, Roxanne E. Kieltyka, Albert M. Brouwer, Marta M. Natile and Sylvestre Bonnet

Langmuir, 2019, 35, 12079
DOI: 10.1021/acs.langmuir.9b01318

Oxygen self-sufficient photodynamic therapy

Fangmian Wei, Thomas W. Rees, Xinxing Liao, Liangnian Ji and Hui Chao

Coordination Chemistry Reviews, 2021, 432, 213714
DOI: 10.1016/j.ccr.2020.213714

Cyclometalated Gold(III)‐Hydride Complexes Exhibit Visible Light‐Induced Thiol Reactivity and Act as Potent Photo‐Activated Anti‐Cancer Agents

Hejiang Luo, Bei Cao, Albert S. C. Chan, Raymond Wai‐Yin Sun and Taotao Zou

Angewandte Chemie, 2020, 132, 11139
DOI: 10.1002/ange.202000528

Classification of Metal-Based Drugs according to Their Mechanisms of Action

Eszter Boros, Paul J. Dyson and Gilles Gasser

Chem, 2020, 6, 41
DOI: 10.1016/j.chempr.2019.10.013

Photoactivatable Small‐Molecule Inhibitors for Light‐Controlled TAM Kinase Activity

Julie Le Bescont, Liliane Mouawad, Thomas Boddaert, Sophie Bombard and Sandrine Piguel

ChemPhotoChem, 2021, 5, 989
DOI: 10.1002/cptc.202100131

Polymeric Encapsulation of Novel Homoleptic Bis(dipyrrinato) Zinc(II) Complexes with Long Lifetimes for Applications as Photodynamic Therapy Photosensitisers

Johannes Karges, Uttara Basu, Olivier Blacque, Hui Chao and Gilles Gasser

Angew Chem Int Ed, 2019, 58, 14334
DOI: 10.1002/anie.201907856

Toward the Treatment of Glioblastoma Tumors Using Photoactivated Chemotherapy: In Vitro Evaluation of Efficacy and Safety

Sina Katharina Goetzfried, Matthijs L. A. Hakkennes, Anja Busemann and Sylvestre Bonnet

ACS Pharmacol. Transl. Sci., 2025, 8, 484
DOI: 10.1021/acsptsci.4c00600

Design, Synthesis, and Bioevaluation of Novel Reversibly Photoswitchable PI3K Inhibitors Based on Phenylazopyridine Derivatives toward Light-Controlled Cancer Treatment

Yan Zhang, Jialing Deng, Hua Tian, Haixiang Qi, Tianning Xiong, Songwen Lin, Yi Dong, Lijun Luo, Deyu Wu, Kehui Zhang, Ming Ji, Tingting Du, Li Sheng, Xiaoguang Chen and Heng Xu

J. Med. Chem., 2024, 67, 3504
DOI: 10.1021/acs.jmedchem.3c01864

Partially Solvated Dinuclear Ruthenium Compounds Bridged by Quinoxaline-Functionalized Ligands as Ru(II) Photocage Architectures for Low-Energy Light Absorption

Sayan Saha, Bruno Peña and Kim R. Dunbar

Inorg. Chem., 2019, 58, 14568
DOI: 10.1021/acs.inorgchem.9b02232

Light Triggers the Antiproliferative Activity of Naphthalimide-Conjugated (η6-arene)ruthenium(II) Complexes

Franco Bisceglie, Giorgio Pelosi, Nicolò Orsoni, Marianna Pioli, Mauro Carcelli, Paolo Pelagatti, Silvana Pinelli and Peter J. Sadler

IJMS, 2022, 23, 7624
DOI: 10.3390/ijms23147624

Riboflavin-targeted polymers improve tolerance of paclitaxel while maintaining therapeutic efficacy

Milita Darguzyte, Elena Rama, Anne Rix, Jasmin Baier, Juliane Hermann, Sima Rezvantalab, Mohammad Khedri, Joachim Jankowski and Fabian Kiessling

Nanomedicine: Nanotechnology, Biology and Medicine, 2024, 58, 102751
DOI: 10.1016/j.nano.2024.102751

Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials

Roy Weinstain, Tomáš Slanina, Dnyaneshwar Kand and Petr Klán

Chem. Rev., 2020, 120, 13135
DOI: 10.1021/acs.chemrev.0c00663

Exploring the Impact of Phenanthroline‐Based Glycoconjugated Ru(II) Polypyridyl Photosensitizers on Metastasis‐Related Processes

Elena de la Torre‐Rubio, María‐Selma Arias‐Pérez, Lourdes Gude, Tomás Cuenca, Cristina García‐Iriepa and Eva Royo

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202501105

A 2-(benzothiazol-2-yl)-phenolato platinum(II) complex as potential photosensitizer for combating bacterial infections in lung cancer chemotherapy†

Enrique Ortega, Cristina Pérez-Arnaiz, Venancio Rodríguez, Christoph Janiak, Natalia Busto, Begoña García and José Ruiz

European Journal of Medicinal Chemistry, 2021, 222, 113600
DOI: 10.1016/j.ejmech.2021.113600

DNA-interacting properties of two analogous square-planar cis-chlorido complexes: copper versus palladium

Marcos V. Palmeira-Mello, Ana B. Caballero, Aida Lopez-Espinar, Guilherme P. Guedes, Amparo Caubet, Alessandra M. Teles de Souza, Mauricio Lanznaster and Patrick Gamez

J Biol Inorg Chem, 2021, 26, 727
DOI: 10.1007/s00775-021-01888-2

Light-activated green drugs: How we can use them in photodynamic therapy and mass-produce them with biotechnological tools

Emiliano Foresto, Pamela Gilardi, Luis Exequiel Ibarra and Ingrid Sol Cogno

Phytomedicine Plus, 2021, 1, 100044
DOI: 10.1016/j.phyplu.2021.100044

Photopharmacology of Proteolysis-Targeting Chimeras: A New Frontier for Drug Discovery

Shenxin Zeng, Hongjie Zhang, Zhengrong Shen and Wenhai Huang

Front. Chem., 2021, 9
DOI: 10.3389/fchem.2021.639176

Modulating the Chemical Reactivity of Gold Complexes in Living Systems: From Concept to Biomedical Applications

Jia Jiang, Xiaolin Xiong and Taotao Zou

Acc. Chem. Res., 2023, 56, 1043
DOI: 10.1021/acs.accounts.3c00037

Recent advances in endoplasmic reticulum targeting metal complexes

Can Huang, Tingxuan Li, Jiayu Liang, Huaiyi Huang, Pingyu Zhang and Samya Banerjee

Coordination Chemistry Reviews, 2020, 408, 213178
DOI: 10.1016/j.ccr.2020.213178

Reactivity of a nitrosyl ruthenium complex and its potential impact on the fate of DNA – An in vitro investigation

Patrícia H.R. Martins, Adolfo I.B. Romo, Francisco O.N. da Silva, Otaciro R. Nascimento, Joaquín Rodríguez-López, Izaura C.N. Diógenes, Luiz G.F. Lopes and Eduardo H.S. Sousa

Journal of Inorganic Biochemistry, 2023, 238, 112052
DOI: 10.1016/j.jinorgbio.2022.112052

Alkyne Functionalization of a Photoactivated Ruthenium Polypyridyl Complex for Click-Enabled Serum Albumin Interaction Studies

Anja Busemann, Can Araman, Ingrid Flaspohler, Alessandro Pratesi, Xue-Quan Zhou, Vincent H. S. van Rixel, Maxime A. Siegler, Luigi Messori, Sander I. van Kasteren and Sylvestre Bonnet

Inorg. Chem., 2020, 59, 7710
DOI: 10.1021/acs.inorgchem.0c00742

Oxoplatin-B, a cisplatin-based platinum(IV) complex with photoactive BODIPY for mitochondria specific “chemo-PDT” activity

Arpan Bera, Srishti Gautam, Md Kausar Raza, Paturu Kondaiah and Akhil R. Chakravarty

Journal of Inorganic Biochemistry, 2021, 223, 111526
DOI: 10.1016/j.jinorgbio.2021.111526

Clinical Development of Metal Complexes as Photosensitizers for Photodynamic Therapy of Cancer

Johannes Karges

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202112236

Converting an Almost Noncytotoxic Ru(II) Complex with Photolabile Ligands into a Highly Efficient PACT Agent

Shuang Qi, Zhihui Jin, Yuanjun Hou, Chao Li, Xuesong Wang and Qianxiong Zhou

Part & Part Syst Charact, 2021, 38
DOI: 10.1002/ppsc.202100193

Cyclometalated gold(III)‐hydride under oriented external electric fields: a new strategy to modulate its reactivity?

Yin‐Qi Li, Xin Cheng, Shan Jiang, Wen‐Xuan Song, Jing‐Hua Chen and Wei‐Ming Sun

Chemistry A European J, 2024, 30
DOI: 10.1002/chem.202303568

Direct and indirect approaches to red-shift photoactivated nitric oxide release

Hani M. Elbeheiry and Martin Schulz

Coordination Chemistry Reviews, 2024, 515, 215921
DOI: 10.1016/j.ccr.2024.215921

The photoactivity of natural products – An overlooked potential of phytomedicines?

Bianka Siewert and Hermann Stuppner

Phytomedicine, 2019, 60, 152985
DOI: 10.1016/j.phymed.2019.152985

Cyclometalated Gold(III)‐Hydride Complexes Exhibit Visible Light‐Induced Thiol Reactivity and Act as Potent Photo‐Activated Anti‐Cancer Agents

Hejiang Luo, Bei Cao, Albert S. C. Chan, Raymond Wai‐Yin Sun and Taotao Zou

Angew Chem Int Ed, 2020, 59, 11046
DOI: 10.1002/anie.202000528

Selective Preparation of a Heteroleptic Cyclometallated Ruthenium Complex Capable of Undergoing Photosubstitution of a Bidentate Ligand

Jordi‐Amat Cuello‐Garibo, Catriona C. James, Maxime A. Siegler, Samantha L. Hopkins and Sylvestre Bonnet

Chemistry A European J, 2019, 25, 1260
DOI: 10.1002/chem.201803720

Klinische Entwicklung von Metallkomplexen als Photosensibilisatoren für die photodynamische Therapie von Krebs

Johannes Karges

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202112236

Single-Cell Chemistry of Photoactivatable Platinum Anticancer Complexes

Elizabeth M. Bolitho, Carlos Sanchez-Cano, Huayun Shi, Paul D. Quinn, Maria Harkiolaki, Cinzia Imberti and Peter J. Sadler

J. Am. Chem. Soc., 2021, 143, 20224
DOI: 10.1021/jacs.1c08630

Photoactivatable Ruthenium Complexes Containing Minimal Straining Benzothiazolyl-1,2,3-triazole Chelators for Cancer Treatment

Francisco J. Ballester, Alba Hernández-García, M. Dolores Santana, Delia Bautista, Pezhman Ashoo, Enrique Ortega-Forte, Giampaolo Barone and José Ruiz

Inorg. Chem., 2024, 63, 6202
DOI: 10.1021/acs.inorgchem.3c04432

Molecular folding governs switchable singlet oxygen photoproduction in porphyrin-decorated bistable rotaxanes

Jan Riebe, Benedikt Bädorf, Sarah Löffelsender, Matias E. Gutierrez Suburu, María Belén Rivas Aiello, Cristian A. Strassert, Stefan Grimme and Jochen Niemeyer

Commun Chem, 2024, 7
DOI: 10.1038/s42004-024-01247-7

Generation and Application of Reactive Oxygen Radicals in Cancer Treatment

Taniya Patial, Niharika Sharma, Kunal Sharma and Vivek Mishra

ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202403648

Fine‐Feature Modifications to Strained Ruthenium Complexes Radically Alter Their Hypoxic Anticancer Activity†

Houston D. Cole, John A. Roque, Liubov M. Lifshits, Rachel Hodges, Patrick C. Barrett, Dmytro Havrylyuk, David Heidary, Elamparuthi Ramasamy, Colin G. Cameron, Edith C. Glazer and Sherri A. McFarland

Photochem & Photobiology, 2022, 98, 73
DOI: 10.1111/php.13395

Organogold(III) Complexes Display Conditional Photoactivities: Evolving From Photodynamic into Photoactivated Chemotherapy in Response to O2Consumption for Robust Cancer Therapy

Yunli Luo, Bei Cao, Mingjie Zhong, Moyi Liu, Xiaolin Xiong and Taotao Zou

Angewandte Chemie, 2022, 134
DOI: 10.1002/ange.202212689

Computational Assessment of Novel Ruthenium Phenoxazine‐Based Complexes as Photosensitizers in Photodynamic Therapy

Pierraffaele Barretta, Fortuna Ponte, Stefano Scoditti and Gloria Mazzone

Eur J Inorg Chem, 2024, 27
DOI: 10.1002/ejic.202400309

Chain photosolvation of trans,trans,trans-[PtIV(py)2(N3)2(OH)2] complex prospective as a light-activated antitumor agent

Grigory I. Zhdankin, Vjacheslav P. Grivin, Victor F. Plyusnin, Pavel A. Tkachenko, Danila B. Vasilchenko and Evgeni M. Glebov

Mendeleev Communications, 2023, 33, 61
DOI: 10.1016/j.mencom.2023.01.019

Towards Light‐Activated Ruthenium–Arene (RAPTA‐Type) Prodrug Candidates

Anna K. Renfrew, Johannes Karges, Rosario Scopelliti, Felix D. Bobbink, Patrycja Nowak‐Sliwinska, Gilles Gasser and Paul J. Dyson

ChemBioChem, 2019, 20, 2876
DOI: 10.1002/cbic.201900236

Photoaquation of cis-[Rh(dppz)(phen)Cl2]Cl complex prospective as potential light-activated anti-cancer agent

Iuliia Malakhova, Evgenia Polyakova, Danila Vasilchenko, Vjacheslav Grivin, Ivan Pozdnyakov, Andrei Kokorenko, Alexei Melnikov, Sergei Chekalin and Evgeni Glebov

Journal of Photochemistry and Photobiology A: Chemistry, 2024, 452, 115621
DOI: 10.1016/j.jphotochem.2024.115621

Polymeric Encapsulation of a Ru(II)-Based Photosensitizer for Folate-Targeted Photodynamic Therapy of Drug Resistant Cancers

Johannes Karges, Mickaël Tharaud and Gilles Gasser

J. Med. Chem., 2021, 64, 4612
DOI: 10.1021/acs.jmedchem.0c02006

Photochemistry of cis,trans-[PtIV(en)(I)2(CH3COO)2] complex in aqueous solutions

E. M. Glebov, I. P. Pozdnyakov, I. M. Magin, V. P. Grivin, V. F. Plyusnin, D. B. Vasil’chenko, A. V. Zadesenets, A. A. Mel’nikov and S. V. Chekalin

Russ Chem Bull, 2019, 68, 1532
DOI: 10.1007/s11172-019-2588-y

Dual-Action Ru(II) Complexes with Bulky π-Expansive Ligands: Phototoxicity without DNA Intercalation

Nicholas P. Toupin, Sandeep Nadella, Sean J. Steinke, Claudia Turro and Jeremy J. Kodanko

Inorg. Chem., 2020, 59, 3919
DOI: 10.1021/acs.inorgchem.9b03585

Neue lichtaktivierte Wirkstoffe

Michael Groß

Nachr Chem, 2019, 67, 58
DOI: 10.1002/nadc.20194087328

New Designs for Phototherapeutic Transition Metal Complexes

Cinzia Imberti, Pingyu Zhang, Huaiyi Huang and Peter J. Sadler

Angewandte Chemie, 2020, 132, 61
DOI: 10.1002/ange.201905171

Antitumor Immune Response Triggered by Metal-Based Photosensitizers for Photodynamic Therapy: Where Are We?

Alain C. Jung, Fabien Moinard-Butot, Chloé Thibaudeau, Gilles Gasser and Christian Gaiddon

Pharmaceutics, 2021, 13, 1788
DOI: 10.3390/pharmaceutics13111788

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

Nkune Williams Nkune and Heidi Abrahamse

Journal of Biophotonics, 2025, 18
DOI: 10.1002/jbio.70005

Ruthenium-Cathepsin Inhibitor Conjugates for Green Light-Activated Photodynamic Therapy and Photochemotherapy

Madeline Denison, Santana P. Garcia, Alexander Ullrich, Izabela Podgorski, Heather Gibson, Claudia Turro and Jeremy J. Kodanko

Inorg. Chem., 2024, 63, 7973
DOI: 10.1021/acs.inorgchem.4c01008

Toward Optimal Ru(II) Photocages: Balancing Photochemistry, Stability, and Biocompatibility Through Fine Tuning of Steric, Electronic, and Physiochemical Features

Dmytro Havrylyuk, Kimberly Stevens, Sean Parkin and Edith C. Glazer

Inorg. Chem., 2020, 59, 1006
DOI: 10.1021/acs.inorgchem.9b02065

The Role of Triplet States in the Photodissociation of a Platinum Azide Complex by a Density Matrix Renormalization Group Method

Leon Freitag and Leticia González

J. Phys. Chem. Lett., 2021, 12, 4876
DOI: 10.1021/acs.jpclett.1c00829

Recent progress in ligand photorelease reaction mechanisms: Theoretical insights focusing on Ru(II) 3MC states

Adrien Soupart, Fabienne Alary, Jean-Louis Heully, Paul I.P. Elliott and Isabelle M. Dixon

Coordination Chemistry Reviews, 2020, 408, 213184
DOI: 10.1016/j.ccr.2020.213184

Biotin-tagged cis-dichlorido-oxidovanadium(IV) complex for DNA crosslinking and photo-induced apoptotic cytotoxicity

Arun Kumar, Somarupa Sahoo, Akanksha Dixit, Anjali A. Karande and Akhil R. Chakravarty

Inorganica Chimica Acta, 2021, 528, 120629
DOI: 10.1016/j.ica.2021.120629

Functionalized azobenzene platinum(II) complexes as putative anticancer compounds

Katia G. Samper, Julia Lorenzo, Mercè Capdevila, Òscar Palacios and Pau Bayón

J Biol Inorg Chem, 2021, 26, 435
DOI: 10.1007/s00775-021-01865-9

Unlocking the Potential of Ru(II) Dual‐action Compounds with the Power of the Heavy‐atom Effect†

Nicholas P. Toupin, Sean J. Steinke, Mackenzie K Herroon, Izabela Podgorski, Claudia Turro and Jeremy J. Kodanko

Photochem & Photobiology, 2022, 98, 378
DOI: 10.1111/php.13573

Optical modulation of cell nucleus penetration and singlet oxygen release of a switchable platinum complex

Zakaria Ziani, Saioa Cobo, Nathalie Berthet and Guy Royal

iScience, 2024, 27, 108704
DOI: 10.1016/j.isci.2023.108704

Trinuclear ruthenium(II) polypyridyl complexes: Evaluation as photosensitizers for enhanced cervical cancer treatment

Athi Welsh, Refilwe Matshitse, Saif F. Khan, Tebello Nyokong, Sharon Prince and Gregory S. Smith

Journal of Inorganic Biochemistry, 2024, 256, 112545
DOI: 10.1016/j.jinorgbio.2024.112545

Photophysical properties of heavy atom containing tetrasulfonyl phthalocyanines as possible photosensitizers in photodynamic therapy

Bruna Clara De Simone, Marta Erminia Alberto, Nino Russo and Marirosa Toscano

J Comput Chem, 2021, 42, 1803
DOI: 10.1002/jcc.26714

Cisplatin: The first metal based anticancer drug

Sumit Ghosh

Bioorganic Chemistry, 2019, 88, 102925
DOI: 10.1016/j.bioorg.2019.102925

Os(II) Oligothienyl Complexes as a Hypoxia-Active Photosensitizer Class for Photodynamic Therapy

John A. Roque, Patrick C. Barrett, Houston D. Cole, Liubov M. Lifshits, Evan Bradner, Ge Shi, David von Dohlen, Susy Kim, Nino Russo, Gagan Deep, Colin G. Cameron, Marta E. Alberto and Sherri A. McFarland

Inorg. Chem., 2020, 59, 16341
DOI: 10.1021/acs.inorgchem.0c02137

Visible-Light-Controlled Histone Deacetylase Inhibitors for Targeted Cancer Therapy

Laia Josa-Culleré and Amadeu Llebaria

J. Med. Chem., 2023, 66, 1909
DOI: 10.1021/acs.jmedchem.2c01713

Characterization and Biological Activity of a Hydrogen Sulfide-Releasing Red Light-Activated Ruthenium(II) Complex

Joshua J. Woods, Jian Cao, Alexander R. Lippert and Justin J. Wilson

J. Am. Chem. Soc., 2018, 140, 12383
DOI: 10.1021/jacs.8b08695

One‐ and Two‐Photon Phototherapeutic Effects of RuII Polypyridine Complexes in the Hypoxic Centre of Large Multicellular Tumor Spheroids and Tumor‐Bearing Mice**

Johannes Karges, Shi Kuang, Yih Ching Ong, Hui Chao and Gilles Gasser

Chemistry A European J, 2021, 27, 362
DOI: 10.1002/chem.202003486

Flipping the Switch: Innovations in Inducible Probes for Protein Profiling

Sean M. McKenna, Ellen M. Fay and Joanna F. McGouran

ACS Chem. Biol., 2021, 16, 2719
DOI: 10.1021/acschembio.1c00572

Computational Studies of the Photogeneration from Dihydrosanguinarine and the Probable Cytotoxicity Mechanism of Sanguinarine

Stefano Scoditti, Simone Bruno, Emilia Sicilia and Gloria Mazzone

Applied Sciences, 2022, 12, 1095
DOI: 10.3390/app12031095

Relevance of Fluorinated Ligands to the Design of Metallodrugs for Their Potential Use in Cancer Treatment

José C. Páez-Franco, Miriam R. Zermeño-Ortega, Carmen Myriam de la O-Contreras, Daniel Canseco-González, Jesus R. Parra-Unda, Alcives Avila-Sorrosa, Raúl G. Enríquez, Juan M. Germán-Acacio and David Morales-Morales

Pharmaceutics, 2022, 14, 402
DOI: 10.3390/pharmaceutics14020402

Unveiling the Photophysical and Photochemical Reaction Process of Naproxen via Ultrafast Femtosecond to Nanosecond Laser Flash Photolysis

Runhui Liang, Shan-Shan Sun, Guanheng Huang and Ming-De Li

Chem. Res. Toxicol., 2019, 32, 613
DOI: 10.1021/acs.chemrestox.8b00310

X-ray tomography of cryopreserved human prostate cancer cells: mitochondrial targeting by an organoiridium photosensitiser

Elizabeth M. Bolitho, Carlos Sanchez-Cano, Huaiyi Huang, Ian Hands-Portman, Matthew Spink, Paul D. Quinn, Maria Harkiolaki and Peter J. Sadler

J Biol Inorg Chem, 2020, 25, 295
DOI: 10.1007/s00775-020-01761-8

Acetylacetonate Ruthenium Nitrosyls: A Gateway to Nitric Oxide Release in Water under Near-Infrared Excitation by Two-Photon Absorption

Pablo Labra-Vázquez, Vladyslav Mudrak, Marine Tassé, Sonia Mallet-Ladeira, Alix Sournia-Saquet, Jean-Pierre Malval, Pascal G. Lacroix and Isabelle Malfant

Inorg. Chem., 2023, 62, 20349
DOI: 10.1021/acs.inorgchem.3c03355

Dynamics of Oxygen-Independent Photocleavage of Blebbistatin as a One-Photon Blue or Two-Photon Near-Infrared Light-Gated Hydroxyl Radical Photocage

Ming-De Li, Nai-Kei Wong, Jia Xiao, Ruixue Zhu, Liangliang Wu, Sheng-Yao Dai, Feng Chen, Guanheng Huang, Liang Xu, Xiaoyu Bai, Margarita R. Geraskina, Arthur H. Winter, Xuebo Chen, Yingxia Liu, Weihai Fang, Dan Yang and David Lee Phillips

J. Am. Chem. Soc., 2018, 140, 15957
DOI: 10.1021/jacs.8b10235

A red light‐activable MnI(CO)3‐functionalized gold nanocomposite as the anticancer prodrug with theranostic potential

Dulal Musib, Md Kausar Raza, Mrityunjoy Pal and Mithun Roy

Applied Organom Chemis, 2021, 35
DOI: 10.1002/aoc.6110

Combination of light and Ru(II) polypyridyl complexes: Recent advances in the development of new anticancer drugs

Luca Conti, Eleonora Macedi, Claudia Giorgi, Barbara Valtancoli and Vieri Fusi

Coordination Chemistry Reviews, 2022, 469, 214656
DOI: 10.1016/j.ccr.2022.214656

Synthesis and In Vitro Studies of Photoactivatable Semisquaraine-type Pt(II) Complexes

Kevin Morales, Sergi Rodríguez-Calado, Jordi Hernando, Julia Lorenzo, Antonio Rodríguez-Diéguez, Carlos Jaime, Pau Nolis, Mercè Capdevila, Òscar Palacios, Marta Figueredo and Pau Bayón

Inorg. Chem., 2022, 61, 7729
DOI: 10.1021/acs.inorgchem.1c03957

Advances in the Design of Photoactivatable Metallodrugs: Excited State Metallomics

Huayun Shi, Rafael C. Marchi and Peter J. Sadler

Angew Chem Int Ed, 2025, 64
DOI: 10.1002/anie.202423335

A Near‐Infrared Light‐Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy

Guangli He, Maomao He, Ran Wang, Xuezhao Li, Hanze Hu, Dongsheng Wang, Ziqian Wang, Yang Lu, Ning Xu, Jianjun Du, Jiangli Fan, Xiaojun Peng and Wen Sun

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202218768

How can the potential of the duocarmycins be unlocked for cancer therapy?

Zoë Jukes, Goreti Ribeiro Morais, Paul M. Loadman and Klaus Pors

Drug Discovery Today, 2021, 26, 577
DOI: 10.1016/j.drudis.2020.11.020

Selective and Efficient Photoinactivation of Intracellular Staphylococcus aureus and MRSA with Little Accumulation of Drug Resistance: Application of a Ru(II) Complex with Photolabile Ligands

Weize Sun, Yao Jian, Mengxue Zhou, Yishan Yao, Na Tian, Chao Li, Jun Chen, Xuesong Wang and Qianxiong Zhou

J. Med. Chem., 2021, 64, 7359
DOI: 10.1021/acs.jmedchem.0c02257

A Near‐Infrared Light‐Activated Photocage Based on a Ruthenium Complex for Cancer Phototherapy

Guangli He, Maomao He, Ran Wang, Xuezhao Li, Hanze Hu, Dongsheng Wang, Ziqian Wang, Yang Lu, Ning Xu, Jianjun Du, Jiangli Fan, Xiaojun Peng and Wen Sun

Angewandte Chemie, 2023, 135
DOI: 10.1002/ange.202218768

Red-Light-Responsive Polypeptoid Nanoassemblies Containing a Ruthenium(II) Polypyridyl Complex with Synergistically Enhanced Drug Release and ROS Generation for Anticancer Phototherapy

Yandong Ma, Zhihua Zhang, Fan Sun, Pierre Mesdom, Xin Ji, Pierre Burckel, Gilles Gasser and Min-Hui Li

Biomacromolecules, 2023, 24, 5940
DOI: 10.1021/acs.biomac.3c00949

Light activation of cyclometalated ruthenium complexes drives towards caspase 3 dependent apoptosis in gastric cancer cells

Jorge Andrés Solís-Ruiz, Anaïs Barthe, Gilles Riegel, Rafael Omar Saavedra-Díaz, Christian Gaiddon and Ronan Le Lagadec

Journal of Inorganic Biochemistry, 2020, 208, 111080
DOI: 10.1016/j.jinorgbio.2020.111080

Metal dipyrrin complexes as potential photosensitizers for photodynamic therapy

Johannes Karges, Olivier Blacque and Gilles Gasser

Inorganica Chimica Acta, 2020, 505, 119482
DOI: 10.1016/j.ica.2020.119482

Metallodrugs as Anticancer Chemotherapeutics and Diagnostic Agents: A Critical Patent Review (2010-2020)

Eirini Fotopoulou, Ioannis Titilas and Luca Ronconi

PRA, 2022, 17, 42
DOI: 10.2174/1574892816666210907101146

DFT Computational Analysis of the Mechanism of Action of Ru(II) Polypyridyl Complexes as Photoactivated Chemotherapy Agents: From Photoinduced Ligand Solvolysis to DNA Binding

Fortuna Ponte, Daniele Belletto, Roberta Leonetti, Nico Sanna, Stefano Scoditti, Gloria Mazzone and Emilia Sicilia

Inorg. Chem., 2024, 63, 20643
DOI: 10.1021/acs.inorgchem.4c03297

Bidentate Coordination of 2‐Aminopyridine (2Apy) in cis‐[Ru(phen)2(2Apy)]2+ Aiming at Photobiological Studies

Marcia V. S. Lima, Rafael C. Marchi, Carolina R. Cardoso, Nathan P. Cook, Wallance M. Pazin, Flavio V. C. Kock, Tiago Venâncio, Angel A. Martí and Rose M. Carlos

Eur J Inorg Chem, 2022, 2022
DOI: 10.1002/ejic.202101015

Ru(II) Phenanthroline-Based Oligothienyl Complexes as Phototherapy Agents

Houston D. Cole, Abbas Vali, John A. Roque, Ge Shi, Gurleen Kaur, Rachel O. Hodges, Antonio Francés-Monerris, Marta E. Alberto, Colin G. Cameron and Sherri A. McFarland

Inorg. Chem., 2023, 62, 21181
DOI: 10.1021/acs.inorgchem.3c03216

A Multi‐action and Multi‐target RuII–PtIV Conjugate Combining Cancer‐Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers

Johannes Karges, Thirumal Yempala, Mickaël Tharaud, Dan Gibson and Gilles Gasser

Angewandte Chemie, 2020, 132, 7135
DOI: 10.1002/ange.201916400

Approaches towards understanding the mechanism-of-action of metallodrugs

Xiaolin Xiong, Liu-Yi Liu, Zong-Wan Mao and Taotao Zou

Coordination Chemistry Reviews, 2022, 453, 214311
DOI: 10.1016/j.ccr.2021.214311

Retrieving Proton Beam Information Using Stitching-Based Detector Technique and Intelligent Reconstruction Algorithms

Chi-Wen Hsieh, Hong-Liang Chang, Yi-Hsiang Huang, Ming-Che Lee and Yu-Jen Wang

Sensors, 2025, 25, 4985
DOI: 10.3390/s25164985

Light-activated ruthenium (II)-bicalutamide prodrugs for prostate cancer

Jian Zhao, Nannan Liu, Shuchen Sun, Shaohua Gou, Xinyi Wang, Zhimei Wang, Xiaoyan Li and Wenjing Zhang

Journal of Inorganic Biochemistry, 2019, 196, 110684
DOI: 10.1016/j.jinorgbio.2019.03.024

Advances in the Design of Photoactivatable Metallodrugs: Excited State Metallomics

Huayun Shi, Rafael C. Marchi and Peter J. Sadler

Angewandte Chemie, 2025, 137
DOI: 10.1002/ange.202423335

In the Search for Photocages Cleavable with Visible Light: An Overview of Recent Advances and Chemical Strategies

Laia Josa‐Culleré and Amadeu Llebaria

ChemPhotoChem, 2021, 5, 296
DOI: 10.1002/cptc.202000253

The Development of Ru(II)-Based Photoactivated Chemotherapy Agents

Yongjie Chen, Lijuan Bai, Pu Zhang, Hua Zhao and Qianxiong Zhou

Molecules, 2021, 26, 5679
DOI: 10.3390/molecules26185679

Reversible Photoinduced Ligand Substitution in a Luminescent Chromium(0) Complex

Narayan Sinha, Joël Wellauer, Tamar Maisuradze, Alessandro Prescimone, Stephan Kupfer and Oliver S. Wenger

J. Am. Chem. Soc., 2024, 146, 10418
DOI: 10.1021/jacs.3c13925

Squaramide-Based Pt(II) Complexes as Potential Oxygen-Regulated Light-Triggered Photocages

Kevin Morales, Katia G. Samper, Quim Peña, Jordi Hernando, Julia Lorenzo, Antonio Rodríguez-Diéguez, Mercè Capdevila, Marta Figueredo, Òscar Palacios and Pau Bayón

Inorg. Chem., 2018, 57, 15517
DOI: 10.1021/acs.inorgchem.8b02854

Strained, Photoejecting Ru(II) Complexes that are Cytotoxic Under Hypoxic Conditions

John Roque, Dmytro Havrylyuk, Patrick C. Barrett, Tariq Sainuddin, Julia McCain, Katsuya Colón, William T. Sparks, Evan Bradner, Susan Monro, David Heidary, Colin G. Cameron, Edith C. Glazer and Sherri A. McFarland

Photochem & Photobiology, 2020, 96, 327
DOI: 10.1111/php.13174

Polyphosphoester-stabilized cubosomes encapsulating a Ru(II) complex for the photodynamic treatment of lung adenocarcinoma

Luca Casula, Gina Elena Giacomazzo, Luca Conti, Marco Fornasier, Benedetto Manca, Michele Schlich, Chiara Sinico, Timo Rheinberger, Frederik R. Wurm, Claudia Giorgi and Sergio Murgia

Journal of Colloid and Interface Science, 2024, 670, 234
DOI: 10.1016/j.jcis.2024.05.088

A New Hetero‐Bimetallic [Fe(III)‐Mn(I)] Complex as a Dual Modality, Theranostic Tool for Photoactivated Anticancer Therapy

Abhishek Panwar, Aarti Upadhyay, Moubani Mukherjee, Phamdom Romabai Chanu and Mithun Roy

Applied Organom Chemis, 2025, 39
DOI: 10.1002/aoc.7881

In silico study of active delivery of a photodynamic therapy drug targeting the folate receptor

Basak Koca Fındık, Elise Lognon, Saron Catak and Antonio Monari

Photochem Photobiol Sci, 2025, 24, 1127
DOI: 10.1007/s43630-025-00745-4

Dual Photoreactive Ternary Ruthenium(II) Terpyridyl Complexes: A Comparative Study on Visible-Light-Induced Single-Step Dissociation of Bidentate Ligands and Generation of Singlet Oxygen

Pritha Chatterjee, Ramranjan Mishra, Sakshi Chawla, Avinash Kumar Sonkar, Arijit K. De and Ashis K. Patra

Inorg. Chem., 2024, 63, 14998
DOI: 10.1021/acs.inorgchem.4c01727

Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group

Adiki Raja Sekhar, Youhei Chitose, Jiří Janoš, Sahar Israeli Dangoor, Andrea Ramundo, Ronit Satchi-Fainaro, Petr Slavíček, Petr Klán and Roy Weinstain

Nat Commun, 2022, 13
DOI: 10.1038/s41467-022-31288-2

Ultrafast photochemical processes in the complex trans,trans,trans-[Ptiv(py)2(N3)2(OH)2]

Grigory I. Zhdankin, Ivan P. Pozdnyakov, Alexander V. Mikheylis, Vjacheslav P. Grivin, Danila B. Vasilchenko, Alexei A. Melnikov, Sergei V. Chekalin and Evgeni M. Glebov

Mendeleev Communications, 2024, 34, 488
DOI: 10.1016/j.mencom.2024.06.006

Pyrene modification enables enhanced two-photon excited ligand dissociation of a Ru(II) complex containing monodentate ligands

Zhihui Jin, Shuang Qi, Xusheng Guo, Yao Jian, Yuanjun Hou, Chao Li, Xuesong Wang and Qianxiong Zhou

Inorganica Chimica Acta, 2021, 524, 120435
DOI: 10.1016/j.ica.2021.120435

Unraveling Mechanism and Enhancing Selectivity of a RuII‐bis‐bipyridyl‐morphocumin Complex with RAFT‐Generated Glycopolymer Exploiting Warburg Effect in Cancer

Souryadip Roy, Soumya Paul, Sujato Mukherjee, Priyadarsi De and Arindam Mukherjee

Chemistry A European J, 2025, 31
DOI: 10.1002/chem.202403695

Dopamine-modified halloysite as new anticancer drug carrier system

Ecem Tansık and Hatice Kaplan Can

p, 2025, 70, 322
DOI: 10.14314/polimery.2025.5.3

A Multi‐action and Multi‐target RuII–PtIV Conjugate Combining Cancer‐Activated Chemotherapy and Photodynamic Therapy to Overcome Drug Resistant Cancers

Johannes Karges, Thirumal Yempala, Mickaël Tharaud, Dan Gibson and Gilles Gasser

Angew Chem Int Ed, 2020, 59, 7069
DOI: 10.1002/anie.201916400

Intracellular Photophysics of an Osmium Complex bearing an Oligothiophene Extended Ligand

Kilian R. A. Schneider, Avinash Chettri, Houston D. Cole, Katharina Reglinski, Jannik Brückmann, John A. Roque, Anne Stumper, Djawed Nauroozi, Sylvia Schmid, Christoffer B. Lagerholm, Sven Rau, Peter Bäuerle, Christian Eggeling, Colin G. Cameron, Sherri A. McFarland and Benjamin Dietzek

Chemistry A European J, 2020, 26, 14844
DOI: 10.1002/chem.202002667

Steric hindrance, ligand ejection and associated photocytotoxic properties of ruthenium(II) polypyridyl complexes

Piedad Herrera-Ramírez, Sarah Alina Berger, Dana Josa, David Aguilà, Ana B. Caballero, Pere Fontova, Vanessa Soto-Cerrato, Manuel Martínez and Patrick Gamez

J Biol Inorg Chem, 2023, 28, 403
DOI: 10.1007/s00775-023-01998-z

Study of the biological activity of photoactive bipyridyl-Ru(II) complexes containing 1,3,5-triaza-7-phosphaadamantane (PTA)

José Manuel Veiga del Pino, Franco Scalambra, Cristina Bermejo-Casadesús, Anna Massaguer, Federico García-Maroto and Antonio Romerosa

Journal of Inorganic Biochemistry, 2023, 246, 112291
DOI: 10.1016/j.jinorgbio.2023.112291

Recent advances on the photo-chemotherapeutic potential of manganese carbonyl complexes

Gobinda Bag, Dulal Musib, Md Kausar Raza, Annie Castonguay and Mithun Roy

Polyhedron, 2024, 249, 116778
DOI: 10.1016/j.poly.2023.116778

Stimuli‐Responsive Metal Complexes for Biomedical Applications

Ivanna Amarsy, Sébastien Papot and Gilles Gasser

Angew Chem Int Ed, 2022, 61
DOI: 10.1002/anie.202205900

Structurally Simple Osmium(II) Polypyridyl Complexes as Photosensitizers for Photodynamic Therapy in the Near Infrared**

Asma Mani, Tao Feng, Albert Gandioso, Robin Vinck, Anna Notaro, Lisa Gourdon, Pierre Burckel, Bruno Saubaméa, Olivier Blacque, Kevin Cariou, Jamel‐Eddine Belgaied, Hui Chao and Gilles Gasser

Angew Chem Int Ed, 2023, 62
DOI: 10.1002/anie.202218347