The category of bifunctional building blocks overrides many others because of their fascinating wide applicability in synthetic chemistry.
This review provides a comprehensive overview of the fundamental concepts and mechanisms underlying ipso reactions, highlighting their significance in contemporary organic chemistry.
In this review, we provide a comprehensive overview of the synthesis of thiopyran family compounds via cycloaddition reactions, with examples spanning from the year 2000 to the present.
A highly diastereoselective synthesis of valuable and challenging O-aryl glycosides is achieved by activating glycosylimidate donors through hydrogen bonding-based non-covalent interactions using pyridinium tetrafluoroborate salt as catalyst.
Benzimidazole is crucial in drug design, with derivatives showing anticancer activity via DNA interaction and enzyme inhibition; SAR studies aim to improve efficacy, selectivity, and reduce toxicity.