Cross Reference Logo
Citations to this article as recorded by CrossRef and RSC Journals (64 citations).

A Narrative Review of Bioactive Hydrogel Microspheres: Ingredients, Modifications, Fabrications, Biological Functions, and Applications
Haohui Li, Lili Yu, Ze Li, Sicheng Li, Ye Liu, Guiwen Qu, Kang Chen, Luqiao Huang, Zongan Li, Jianan Ren, Xiuwen Wu and Jinjian Huang
Small, 2025, 21
DOI: 10.1002/smll.202500426

Engineering Polysaccharide Biomaterials: Modifications and Crosslinking Strategies for Soft Tissue Bioprinting
Sagar Tembadamani, Tarun Shyam Mohan, Greeshma Thrivikraman, Vignesh Muthuvijayan and Snigdha Roy Barman
Macromol. Rapid Commun., 2025, 46
DOI: 10.1002/marc.202500236

Exploring carbohydrate extraction from biomass using deep eutectic solvents: Factors and mechanisms
Yong Liu, Lingling Gao, Lungang Chen, Wenguang Zhou, Chenguang Wang and Longlong Ma
iScience, 2023, 26, 107671
DOI: 10.1016/j.isci.2023.107671

O-alg-THAM/gel hydrogels functionalized with engineered microspheres based on mesenchymal stem cell secretion recruit endogenous stem cells for cartilage repair
Yucong Li, Linlong Li, Ming Wang, Boguang Yang, Baozhen Huang, Shanshan Bai, Xiaoting Zhang, Nan Hou, Haixing Wang, Zhengmeng Yang, Chong Tang, Ye Li, Wayne Yuk-Wai Lee, Lu Feng, Micky D. Tortorella and Gang Li
Bioactive Materials, 2023, 28, 255
DOI: 10.1016/j.bioactmat.2023.05.003

pH dual responsive electrospun fiber loading anthocyanin and nisin for food preservation and monitoring: Regulation in dynamic schiff base networks based on different oxidized sodium alginate
Jiaxin Li, Yiwen Bao, Qiao Jiang, Liang Wang, Ying He, Xu Si and Bin Li
Food Chemistry, 2025, 496, 146765
DOI: 10.1016/j.foodchem.2025.146765

Sprayable, crosslinker-free, and in situ-forming Schiff-based hydrogels based on oxidized sodium alginate and carbohydrazide-modified gelatin for rapid hemostasis
Ji Hye Yoo, Dae Hyeok Yang, Jae Hwan Choi, Haram Nah, Wheemoon Cho, Seung Yeon Lee, Jae Seo Lee, Han-Jun Kim, Gun-Jae Jeong, Heung Jae Chun, Dong Nyoung Heo and Il Keun Kwon
Carbohydrate Polymers, 2026, 373, 124571
DOI: 10.1016/j.carbpol.2025.124571

Exploiting Response Surface Methodology to Engineer the Mechanical Properties of Alginate‐based Hydrogels
Alessio Bucciarelli, Chen Zhao, Xue Bai, Rebekah Kay, Ayşe Latif, Kaye J. Williams and Annalisa Tirella
Macro Materials & Eng, 2025, 310
DOI: 10.1002/mame.202400296

A review of self-healing hydrogels for bone repair and regeneration: Materials, mechanisms, and applications
Bo Li, Chenchen Li, Ziyi Yan, Xiaoling Yang, Wenqian Xiao, Dawei Zhang, Zhongning Liu and Xiaoling Liao
International Journal of Biological Macromolecules, 2025, 287, 138323
DOI: 10.1016/j.ijbiomac.2024.138323

Electroconductive biohybrid hydrogel loaded with anti-inflammatory plasmids and growth factors comprehensively improved the myocardial infarction microenvironment
Zhicun Wang, Yue Wang, Cheng Hu, Wenqi Liu, Wen Zhang, Shuyi He, Li Yang and Yunbing Wang
Chemical Engineering Journal, 2026, 536, 175577
DOI: 10.1016/j.cej.2026.175577

ECM derivatized alginate augmenting bio-functionalities of lyophilized mat for skin and liver wound treatment
Md Sohanur Rahaman, Asuva Arin, Ume Farwa, Myeongki Park, Sang Ho Bae and Byong-Taek Lee
Biomaterials, 2024, 311, 122698
DOI: 10.1016/j.biomaterials.2024.122698

Adoption of polyvinyl alcohol electrospinning materials for skin wound dressing
Shuang Deng, Xing Huang, Zhanrong Kang, Dafeng Xu, Wen Luo and Dejian Li
J Mater Sci: Mater Med, 2025, 36
DOI: 10.1007/s10856-025-06945-9

Effect of Silver Nanoparticles on Nonspecific Proteolysis in the Gastric Mucosa at Ulcerative Damage Modeling
Magomed Khasainovich Gairabekov, Tamerlan Borisovich Vakalishev, Isa Fahriddinovich Khurshidov, Alyona Sergeevna Vasilyeva, Gunel Ilgar Kyzy Imamedova, Madina Baudievna Mamaeva, Tatyana Sergeevna Gambaryan and Aslan Ruslanovich Kazimagomedov
Pharmacophore, 2024, 15, 27
DOI: 10.51847/TDwjSvAV6Q

OAlgMA/GelMA/CaCl2 multinetwork hydrogel scaffolds with enhanced mechanical properties for cartilage injury repair
Bin-an Zhao, Cheng Li, Hengan Ge, Biao Cheng, Huiwen Wu and Jianfeng Pan
Materials & Design, 2026, 261, 115258
DOI: 10.1016/j.matdes.2025.115258

Natural nanogels crosslinked with S-benzyl-L-cysteine exhibit potent antibacterial activity
Fang-Yu Chung, Cheng-Rung Huang, Chang-Shi Chen and Yu-Fon Chen
Biomaterials Advances, 2023, 153, 213551
DOI: 10.1016/j.bioadv.2023.213551

Analysis of effectiveness of the use of multifunctional biopolymers of chitosan and alginate in dentistry ‎
Razin Mirzekerimovich Ragimov, Chermen Tamerlanovich Zakaev, Naida Murtazalievna Abdullaeva, Ruslan Kazbekovich Esiev, Sergey Viktorovich Pushkin, Dana Magomedovna Nauruzova, Mariam Bashirovna Balaeva and Sergey Nikolaevich Povetkin
J Adv Pharm Educ Res, 2022, 12, 21
DOI: 10.51847/yWRLcwYTDC

Three Polymers from the Sea: Unique Structures, Directional Modifications, and Medical Applications
Lei Wang, Wenjun Li and Song Qin
Polymers, 2021, 13, 2482
DOI: 10.3390/polym13152482

Bioactive and degradable hydrogel based on human platelet-rich plasma fibrin matrix combined with oxidized alginate in a diabetic mice wound healing model
Itxaso Garcia-Orue, Edorta Santos-Vizcaino, Pello Sanchez, Francisco Borja Gutierrez, Jose Javier Aguirre, Rosa Maria Hernandez and Manoli Igartua
Biomaterials Advances, 2022, 135, 112695
DOI: 10.1016/j.msec.2022.112695

Bioprinting of structurally organized meniscal tissue within anisotropic melt electrowritten scaffolds
Xavier Barceló, Kian F. Eichholz, Inês F. Gonçalves, Orquidea Garcia and Daniel J. Kelly
Acta Biomaterialia, 2023, 158, 216
DOI: 10.1016/j.actbio.2022.12.047

Tailoring biomaterials for skin anti-aging
Xin Dan, Songjie Li, Han Chen, Ping Xue, Bo Liu, Yikun Ju, Lanjie Lei, Yang Li and Xing Fan
Materials Today Bio, 2024, 28, 101210
DOI: 10.1016/j.mtbio.2024.101210

Bilayer oxidized sodium alginate–carboxymethyl chitosan hydrogel microspheres enable sustained BMP-2 release for enhanced bone regeneration
Yafei Yuan, Xige Zhao, Jiangqi Hu, Yixuan Zhu, Xuening Deng and Qingsong Jiang
Biomed. Mater., 2025, 20, 065009
DOI: 10.1088/1748-605X/ae0778

IMPLICATIONS OF STORAGE CONDITIONS ON THE CHARACTERISTICS OF ALGINATE DIALDEHYDE AND ITS HYDROGELS
Rajalekshmi Resmi, Jayasree Parvathy, Sudha Anjali and Roy Joseph
ChemistrySelect, 2024, 9
DOI: 10.1002/slct.202304419

Alginate-Based Smart Materials and Their Application: Recent Advances and Perspectives
Chandan Maity and Nikita Das
Top Curr Chem (Z), 2022, 380
DOI: 10.1007/s41061-021-00360-8

Peroxynitrite Modification as a Way to Improve the Cytocompatibility of Sodium Alginate-Based Hydrogels
A.S. Zakharov, N.D. Nozadze, I.N. Vasilovsky, N.V. Korotkova, N.D. Mzhavanadze, I.A. Suchkov and R.E. Kalinin
BMCRM, 2024, 7, e00207
DOI: 10.18097/BMCRM00207

Biomedical potential of alginate wound dressings – From preclinical studies to clinical applications: A review
Łukasz Mazurek, Monika Kuś, Jan Jurak, Mateusz Rybka, Marta Kuczeriszka, Monika Stradczuk-Mazurek and Marek Konop
International Journal of Biological Macromolecules, 2025, 309, 142908
DOI: 10.1016/j.ijbiomac.2025.142908

Alginate modifying enzymes: An updated comprehensive review of the mannuronan C5-epimerases
Shengsheng Cao, Li Li, Benwei Zhu and Zhong Yao
Algal Research, 2023, 69, 102952
DOI: 10.1016/j.algal.2022.102952

Modification of Alginates to Modulate Their Physic-Chemical Properties and Obtain Biomaterials with Different Functional Properties
Piotr Rosiak, Ilona Latanska, Paulina Paul, Witold Sujka and Beata Kolesinska
Molecules, 2021, 26, 7264
DOI: 10.3390/molecules26237264

A Novel 3D Bioprinting Crosslinking Method Based on Solenoid Valve Control
Jiaxin Wu, Luxiao Sang, Rihui Kang, Meng Li, Caiwang Cheng, Anguo Liu, Jianlong Ji and Aoqun Jian
Macromolecular Bioscience, 2025, 25
DOI: 10.1002/mabi.202500039

Investigating the Effect of Processing and Material Parameters of Alginate Dialdehyde-Gelatin (ADA-GEL)-Based Hydrogels on Stiffness by XGB Machine Learning Model
Duygu Ege and Aldo R. Boccaccini
Bioengineering, 2024, 11, 415
DOI: 10.3390/bioengineering11050415

Microgels of alginate dialdehyde with WGA lectin conjugate for curcumin encapsulation
Arlina Prima Putri, Marissa Angelina, Mochamad Chalid, Francesco Picchioni and Hero Jan Heeres
Journal of Drug Delivery Science and Technology, 2025, 106, 106717
DOI: 10.1016/j.jddst.2025.106717

Biomaterials for Drug Delivery and Human Applications
Paolo Trucillo
Materials, 2024, 17, 456
DOI: 10.3390/ma17020456

Exploring spectroscopy’s impact in pharmaceutical, and biomedical sciences: an insightful review
Anusree S. Gangadharan, V. M. Adhithya Venu, T. Daniel Thangadurai and Yong-Ill Lee
Applied Spectroscopy Reviews, 2025, 60, 919
DOI: 10.1080/05704928.2025.2485281

Degradation-Kinetics-Controllable and Tissue-Regeneration-Matchable Photocross-linked Alginate Hydrogels for Bone Repair
Delu Zhao, Xin Wang, Bo Cheng, Miaomiao Yin, Zhiqiang Hou, Xiaobao Li, Kun Liu, Chaorong Tie and Miao Yin
ACS Appl. Mater. Interfaces, 2022, 14, 21886
DOI: 10.1021/acsami.2c01739

Formulation and Characterization of a Novel Oxidized Alginate-Gelatin-Silk Fibroin Bioink with the Aim of Skin Regeneration
Khadijeh Sanaei, Ali Zamanian, Shohreh Mashayekhan and Tayebe Ramezani
IBJ, 2023, 27, 280
DOI: 10.61186/ibj.27.5.280

The characterization of molecular weight distribution and aggregation by asymmetrical flow field-flow fractionation of unmodified and oxidized alginate
Chen Zhao, Ayse Latif, Kaye J. Williams and Annalisa Tirella
Reactive and Functional Polymers, 2022, 175, 105292
DOI: 10.1016/j.reactfunctpolym.2022.105292

Harnessing Oxidized Alginate Microgels for Rapid and Self‐Assembling Dental Tissue Organogenesis In Vitro and In Vivo
Chao Liang, Shuxuan Wu, Ziqi Huang, Zhenzhen Wu, Siyuan Chen, Feiming Li, Karrie Mei‐Yee Kiang, Gilberto Ka‐Kit Leung, Indong Jun, Hwan D. Kim, Ann‐Na Cho, Hee Jung Lee, Honghyun Park, Yiu Yan Leung, Seong Jun Kim, Seil Sohn, Haram Nah, Jae Seo Lee, Il Keun Kwon, Dong‐Nyoung Heo, Sang‐woo Lee, Zhaoming Wu and Sang Jin Lee
Small Science, 2025, 5
DOI: 10.1002/smsc.202500053

Partially Oxidized Alginate as a Biodegradable Carrier for Glucose‐Responsive Insulin Delivery and Islet Cell Replacement Therapy
Lisa R. Volpatti, Matthew A. Bochenek, Amanda L. Facklam, Delaney M. Burns, Corina MacIsaac, Alexander Morgart, Benjamin Walters, Robert Langer and Daniel G. Anderson
Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202201822

Research Progress of Sodium Alginate-Based Hydrogels in Biomedical Engineering
Juan Cao, Bo Wu, Ping Yuan, Yeqi Liu and Cheng Hu
Gels, 2025, 11, 758
DOI: 10.3390/gels11090758

Platelet‐Rich Plasma Loaded Alginate‐Based Injectable Hydrogel for Meniscal Tear Repair: In Vivo Evaluation in Lapine Model
Rajalekshmi Resmi, Jayasree Parvathy, Sudha Anjali, Natarajan Amrita, Arun Jyothi, V. S. Harikrishnan, Annie John and Roy Joseph
J Biomed Mater Res, 2025, 113
DOI: 10.1002/jbm.b.35541

Fish scale containing alginate dialdehyde-gelatin bioink for bone tissue engineering
Aylin Kara Özenler, Thomas Distler, Funda Tihminlioglu and Aldo R Boccaccini
Biofabrication, 2023, 15, 025012
DOI: 10.1088/1758-5090/acb6b7

Polysaccharide-inspired biomaterials for skeletal muscle regeneration: innovations for volumetric muscle loss treatment
Yantong Li, Jianan Chen, Shuo Chen, Xue Ding, Xinfeng Zhou, Jin Li, Tingting Zhu, Yong Xu and Fan He
Acta Biomaterialia, 2026, 210, 355
DOI: 10.1016/j.actbio.2025.12.019

Molecular signaling pathways in osteoarthritis and biomaterials for cartilage regeneration: a review
Samson Prince Hiruthyaswamy, Arohi Bose, Ayushi Upadhyay, Tiasa Raha, Shangomitra Bhattacharjee, Isheeta Singha, Swati Ray, Nazarene Marylene Nicky Macarius, Pragasam Viswanathan and Kanagavel Deepankumar
Bioengineered, 2025, 16
DOI: 10.1080/21655979.2025.2501880

Oxidized sodium alginate cross-linked calcium alginate/antarctic krill protein composite fiber for improving strength and water resistance
Zheng Li, Jing Guo, Fucheng Guan, Juhui Yin, Qiang Yang, Sen Zhang, Jun Tian, Yihang Zhang, Mingfei Ding and Wenming Wang
Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2023, 656, 130317
DOI: 10.1016/j.colsurfa.2022.130317

Alginate: Microbial production, functionalization, and biomedical applications
Jianfei Wang, Shijie Liu, Jiaqi Huang, Kexin Ren, Yan Zhu and Siying Yang
International Journal of Biological Macromolecules, 2023, 242, 125048
DOI: 10.1016/j.ijbiomac.2023.125048

Rational design of viscoelastic hydrogels for periodontal ligament remodeling and repair
Songbai Zhang, Jingyi Liu, Fan Feng, Yuanbo Jia, Feng Xu, Zhao Wei and Min Zhang
Acta Biomaterialia, 2024, 174, 69
DOI: 10.1016/j.actbio.2023.12.017

High-Voltage Electrostatic Field Hydrogel Microsphere 3D Culture System Improves Viability and Liver-like Properties of HepG2 Cells
Yi Liu, Yang Ge, Yanfan Wu, Yongtong Feng, Han Liu, Wei Cao, Jinsong Xie and Jingzhong Zhang
IJMS, 2024, 25, 1081
DOI: 10.3390/ijms25021081

Adhesive hydrogels in osteoarthritis: from design to application
Wang-Lin Duan, Li-Ning Zhang, Raghvendra Bohara, Sergio Martin-Saldaña, Fei Yang, Yi-Yang Zhao, Yong Xie, Ya-Zhong Bu and Abhay Pandit
Military Med Res, 2023, 10
DOI: 10.1186/s40779-022-00439-3

Cuttlefish bone derived hydroxyapatite-integrated alginate membrane for hemostasis and regeneration
Meenakshi Perikaruppan, Saheb Ali and Chitra Shivalingam
Inorganic Chemistry Communications, 2024, 168, 112770
DOI: 10.1016/j.inoche.2024.112770

Self-Healing Alginate Hydrogel Formed by Dynamic Benzoxaborolate Chemistry Protects Retinal Pigment Epithelium Cells against Oxidative Damage
Minhua Liu, Yate Huang, Chunwen Tao, Weijia Yang, Junrong Chen, Li Zhu, Tonghe Pan, Ravin Narain, Kaihui Nan and Yangjun Chen
Gels, 2022, 9, 24
DOI: 10.3390/gels9010024

Poly(vinyl alcohol)/sodium alginate polymer membranes as eco‐friendly and biodegradable coatings for slow release fertilizers
Wen Meng, Xu Zhang, Yang Zhang, Xianglu Zhang, Wending Zhu, Handa Huang, Xiaozhao Han, Yahua Liu and Chao Xu
J Sci Food Agric, 2023, 103, 3592
DOI: 10.1002/jsfa.12312

Modification, 3D printing process and application of sodium alginate based hydrogels in soft tissue engineering: A review
Qinghua Wei, Jiayi Zhou, Yalong An, Mingyang Li, Juan Zhang and Sheng Yang
International Journal of Biological Macromolecules, 2023, 232, 123450
DOI: 10.1016/j.ijbiomac.2023.123450

Biomedical potentials of alginate via physical, chemical, and biological modifications
Qiao-Qiao Li, Dong Xu, Qin-Wei Dong, Xu-Jiao Song, Yi-Bing Chen and Yuan-Lu Cui
International Journal of Biological Macromolecules, 2024, 277, 134409
DOI: 10.1016/j.ijbiomac.2024.134409

A bioactive composite sponge based on biomimetic collagen fibril and oxidized alginate for noncompressible hemorrhage and wound healing
Xiaoxia Zhang, Changkai Yang, Xingling Zeng and Guoying Li
Carbohydrate Polymers, 2024, 343, 122409
DOI: 10.1016/j.carbpol.2024.122409

Enhanced spinal cord injury repair by nerve extracellular matrix/carboxymethyl chitosan /oxidized alginate hydrogel containing OE-MSCs
Elham Seidkhani, Soraya Mehrabi, Fatemeh Moradi, Rafieh Alizadeh, Mohamad Pezeshki-Modaress and Mohammad Taghi Joghataei
Carbohydrate Polymers, 2026, 373, 124652
DOI: 10.1016/j.carbpol.2025.124652

Dual-crosslinked in-situ forming alginate/silk fibroin hydrogel with potential for bone tissue engineering
Mina Ghorbani, Ebrahim Vasheghani-Farahani, Negar Azarpira, Sameereh Hashemi-Najafabadi and Amin Ghasemi
Biomaterials Advances, 2023, 153, 213565
DOI: 10.1016/j.bioadv.2023.213565

Advances in the Development of Granular Microporous Injectable Hydrogels with Non‐spherical Microgels and Their Applications in Tissue Regeneration
Haiyan Li, Keerthi Subramanian Iyer, Lei Bao, Jiali Zhai and Jiao Jiao Li
Adv Healthcare Materials, 2024, 13
DOI: 10.1002/adhm.202301597

Biodegradable Mulch Film With Improved Mechanical and Barrier Properties for Sustainable Agricultural
Mingjia Feng, Yunhai Ma, Shichao Niu and Yuqi Zhuansun
J of Applied Polymer Sci, 2025, 142
DOI: 10.1002/app.57436

Research Progress on Injectable Microspheres as New Strategies for the Treatment of Osteoarthritis Through Promotion of Cartilage Repair
Jianjing Lin, Shicheng Jia, Fuyang Cao, Jingtao Huang, Jiayou Chen, Juan Wang, Peng Liu, Hui Zeng, Xintao Zhang and Wenguo Cui
Adv Funct Materials, 2024, 34
DOI: 10.1002/adfm.202400585

Recent Advances in Alginate-Based Hydrogels for Cell Transplantation Applications
Alireza Kavand, François Noverraz and Sandrine Gerber-Lemaire
Pharmaceutics, 2024, 16, 469
DOI: 10.3390/pharmaceutics16040469

Enhanced neurogenic differentiation of human dental pulp stem cells via BDNF-loaded oxidized alginate hydrogel
Nica Jeorgia P. Salazar, Zar Chi Soe, Daneeya Na Nan, Vorasit Vongsutilers, Vorapat Trachoo, Thanaphum Osathanon, João N. Ferreira, Chalida Nakalekha Limjeerajarus and Nuttapol Limjeerajarus
Journal of Dentistry, 2025, 163, 106185
DOI: 10.1016/j.jdent.2025.106185

Alginate-Based Materials Loaded with Nanoparticles in Wound Healing
Anna Froelich, Emilia Jakubowska, Monika Wojtyłko, Barbara Jadach, Michał Gackowski, Piotr Gadziński, Olga Napierała, Yulia Ravliv and Tomasz Osmałek
Pharmaceutics, 2023, 15, 1142
DOI: 10.3390/pharmaceutics15041142

Oxidized Alginate Dopamine Conjugate: A Study to Gain Insight into Cell/Particle Interactions
Adriana Trapani, Filomena Corbo, Erika Stefàno, Loredana Capobianco, Antonella Muscella, Santo Marsigliante, Antonio Cricenti, Marco Luce, David Becerril and Stefano Bellucci
JFB, 2022, 13, 201
DOI: 10.3390/jfb13040201

Novel Injectable, Self-Healing, Long-Effective Bacteriostatic, and Healed-Promoting Hydrogel Wound Dressing and Controlled Drug Delivery Mechanisms
Yufeng Li, Shanqi Chen, Mingdong Zhang, Xiang Ma, Jian Zhao and Yuanhui Ji
ACS Appl. Mater. Interfaces, 2024, 16, 2140
DOI: 10.1021/acsami.3c15705

Hydrogels of Alginate Derivative‐Encased Nanodots Featuring Carbon‐Coated Manganese Ferrite Cores with Gold Shells to Offer Antiangiogenesis with Multimodal Imaging‐Based Theranostics
Pemula Gowtham, Koyeli Girigoswami, Alex Daniel Prabhu, Pragya Pallavi, Anbazhagan Thirumalai, Karthick Harini and Agnishwar Girigoswami
Advanced Therapeutics, 2024, 7
DOI: 10.1002/adtp.202400054

Developing and Characterizing a Biocompatible Hydrogel Obtained by Cross-Linking Gelatin with Oxidized Sodium Alginate for Potential Biomedical Applications
Chahrazed Mahmoudi, Naïma Tahraoui Douma, Hacene Mahmoudi, Camelia Elena Iurciuc (Tincu), Marcel Popa, Mihaela Hamcerencu and Călin Vasile Andrițoiu
Polymers, 2024, 16, 3143
DOI: 10.3390/polym16223143