Novel quinoxaline derivatives as dual EGFR and COX-2 inhibitors: synthesis, molecular docking and biological evaluation as potential anticancer and anti-inflammatory agents

Eman A. Ahmed, Mamdouh F. A. Mohamed and Omran A. Omran

RSC Adv., 2022, 12, 25204
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Synthesis, characterization, photophysical and electrochemical properties, and biomolecular interaction of 2,2′-biquinoline based phototoxic Ru(ii)/Ir(ii) complexes

Utpal Das and Priyankar Paira

Dalton Trans., 2023, 52, 12608
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Copper-catalyzed dehydrogenative cyclization/alkenylation towards dihydroquinolinones

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Org. Biomol. Chem., 2024, 22, 4163
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Quinoline–hydrazone hybrids as dual mutant EGFR inhibitors with promising metallic nanoparticle loading: rationalized design, synthesis, biological investigation and computational studies

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New J. Chem., 2022, 46, 18207
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p-TSA·H2O catalyzed metal-free and environmentally benign synthesis of 4-aryl quinolines from arylamine, arylacetylene, and dimethyl sulfoxide

Simra Faraz and Abu Taleb Khan

Org. Biomol. Chem., 2023, 21, 7553
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Identification of novel furo[2,3-d]pyrimidine based chalcones as potent anti-breast cancer agents: synthesis, in vitro and in vivo biological evaluation

Mai A. Mansour, Mamdouh A. Oraby, Zeinab A. Muhammad, Deena S. Lasheen, Hatem M. Gaber and Khaled A. M. Abouzid

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Design, synthesis, and biological evaluation of novel quinoline-based EGFR/HER-2 dual-target inhibitors as potential anti-tumor agents

Lamya H. Al-Wahaibi, Essmat M. El-Sheref, Hendawy N. Tawfeek, Hesham A. Abou-Zied, Safwat M. Rabea, Stefan Bräse and Bahaa G. M. Youssif

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Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyrimidines derived from quinoline-pyridopyrimidines

Ameen A. Abu-Hashem, Nasser Amri and Ahmed F. El-Sayed

Pharmaceutical Biology, 2025, 63, 607
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Friedlӓnder's synthesis of quinolines as a pivotal step in the development of bioactive heterocyclic derivatives in the current era of medicinal chemistry

Satheeshkumar Rajendran, Kalaiselvi Sivalingam, Rajendra Prasad Karnam Jayarampillai, Wen‐Long Wang and Cristian. O Salas

Chem Biol Drug Des, 2022, 100, 1042
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Synthesis and Anticancer Evaluation of 4-Anilinoquinolinylchalcone Derivatives

Cheng-Yao Yang, Min-Yu Lee, Yeh-Long Chen, Jun-Ping Shiau, Yung-Hsiang Tsai, Chia-Ning Yang, Hsueh-Wei Chang and Chih-Hua Tseng

IJMS, 2023, 24, 6034
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Synthesis, Anticancer, and Molecular Docking Studies of Quinolone‐Thiosemicarbazones Using Fe3O4@gly‐SO3H as a Magnetically Separable Nanocatalyst

Govind Salunke, Pradeep Patil, Nippu B. N., N. D. Satyanarayan, Reshma Yadav, Umesh Sankpal, Shankar Hangirgekar and Sandeep Sankpal

ChemistrySelect, 2025, 10
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Flavokavain C Suppresses Breast Cancer Cell Viability and Induces Cell Apoptosis by Triggering DNA Damage

Xiaoyu Lin, Sunhui Xing, Kejie Chen, Huamao Yang and Xiaoqu Hu

Biological & Pharmaceutical Bulletin, 2023, 46, 684
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Synthesis and characterization of a single crystalline exocyclic double-bonded NLO active chalcone derivative: (2E) -2-(2,4,6-trimethoxybenzylidene) -3,4-dihydro-2H-naphthalene -1-one

D. Reuben Jonathan, S. Balasubramanian, S. Manivannan, Sivalingam Ramesh, J. Irshad Ahamed and N. Afsar

Journal of Molecular Structure, 2023, 1291, 135990
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Focused review on applications of chalcone based compounds in material science

Rachel Alveera Menezes, C. N. Bhuvaneshwari, H. Venkatachalam and K. Subrahmanya Bhat

Discov Appl Sci, 2025, 7
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Synthesis and biological evaluation of bis-chalcone conjugates containing lysine linker as potential anticancer agents

Zhifen Li, Ming Tian, Jingbo Ma, Siyu Xia, Xiannian Lv, Peng Xia, Xiaolong Xu, Yuke Jiang, Jigang Wang and Zhijie Li

Journal of Molecular Structure, 2023, 1288, 135785
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Synthesis of Quinoline and Quinolin-2(1H)-one Derivatives via Nickel Boride Promoted Reductive Cyclization

Rumpa Sarkar, Surya Kanta Samanta, Anila M. Menon, Deepak Chopra, Debabani Ganguly and Mrinal K. Bera

Synthesis, 2023, 55, 3303
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One-pot borylation/arylation of 4-chloroquinolines and its application for the synthesis of various quinoline-based pharmacophores

Pratik Yadav, Sasmita Das, Mariko Saito, Todd Evans and Bhaskar C. Das

Tetrahedron Letters, 2023, 131, 154780
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Novel Multi-Target Agents Based on the Privileged Structure of 4-Hydroxy-2-quinolinone

Ioanna Kostopoulou, Andromachi Tzani, Konstantina Chronaki, Kyriakos C. Prousis, Eleni Pontiki, Dimitra Hadjiplavlou-Litina and Anastasia Detsi

Molecules, 2023, 29, 190
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A Novel Dialkylamino-Functionalized Chalcone, DML6, Inhibits Cervical Cancer Cell Proliferation, In Vitro, via Induction of Oxidative Stress, Intrinsic Apoptosis and Mitotic Catastrophe

Jenna M. Len, Noor Hussein, Saloni Malla, Kyle Mcintosh, Rahul Patidar, Manivannan Elangovan, Karthikeyan Chandrabose, N. S. Hari Narayana Moorthy, Manoj Pandey, Dayanidhi Raman, Piyush Trivedi and Amit K. Tiwari

Molecules, 2021, 26, 4214
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Quinoline‐based thiazolidinone derivatives as potent cytotoxic and apoptosis‐inducing agents through EGFR inhibition

Mohamed S. Nafie, Safaa M. Kishk, Sebaey Mahgoub and Atef M. Amer

Chem Biol Drug Des, 2022, 99, 547
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Multicomponent synthesis of a novel bicyclic pyran-2-one system

Mohammad M. Mojtahedi, Kiana Darvishi, M. Saeed Abaee, Mohammad Eghtedari and Mohammad R. Halvagar

Monatsh Chem, 2022, 153, 501
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Novel Quinoline‐Based RAF Inhibitors: A Comprehensive Review on Synthesis, SAR and Molecular Docking Studies

Adarsh Sahu, Shweta Mishra, Pranay Wal, Biplab Debnath, Deepesh Chouhan, Sachinkumar Dnyaneshwar Gunjal and Arpan Kumar Tripathi

ChemistrySelect, 2024, 9
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3D-QSAR, molecular docking, simulation dynamic and ADMET studies on new quinolines derivatives against colorectal carcinoma activity

Reda El-Mernissi, Ayoub Khaldan, Soukaina Bouamrane, Hafiz Muzzammel Rehman, Marwa Alaqarbeh, Mohammed Aziz Ajana, Tahar Lakhlifi and Mohammed Bouachrine

Journal of Biomolecular Structure and Dynamics, 2024, 42, 3682
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Synthesis, anticancer activity and molecular docking of new quinolines, quinazolines and 1,2,4-triazoles with pyrido[2,3-d] pyrimidines

Ameen Ali Abu-Hashem, Othman Hakami and Nasser Amri

Heliyon, 2024, 10, e26735
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2-Acetyl-5,8-dihydro-6-(4-methyl-3-pentenyl)-1,4-naphthohydroquinone-Derived Chalcones as Potential Anticancer Agents

Javier Maldonado, Alfonso Oliva, Aurora Molinari and Waldo Acevedo

Molecules, 2023, 28, 7172
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Anticancer activities of tetra-, penta-, and hexacyclic phenothiazines modified with quinoline moiety.

Małgorzata Jeleń, Beata Morak-Młodawska and Rafał Korlacki

Journal of Molecular Structure, 2023, 1287, 135700
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Design, synthesis, cytotoxic activities, and molecular docking of chalcone hybrids bearing 8-hydroxyquinoline moiety with dual tubulin/EGFR kinase inhibition

Mohammed M. Amin, Gamal El-Din A. Abuo-Rahma, Montaser Sh. A. Shaykoon, Adel A. Marzouk, Mohammed A.S. Abourehab, Roshdy E. Saraya, Mohamed Badr, Ahmed M. Sayed and Eman A.M. Beshr

Bioorganic Chemistry, 2023, 134, 106444
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Domino Aldol-SNAr-Dehydration Sequence for [3+3] Annulations to Prepare Quinolin-2(1H)-ones and 1,8-Naphthyridin-2(1H)-ones

Kwabena Fobi, Ebenezer Ametsetor and Richard A. Bunce

Molecules, 2023, 28, 5856
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Chalcones, a Privileged Scaffold: Highly Versatile Molecules in [4+2] Cycloadditions

Salvador Mastachi‐Loza, Tania I. Ramírez‐Candelero, Luis J. Benítez‐Puebla, Aydeé Fuentes‐Benítes, Carlos González‐Romero and Miguel A. Vázquez

Chemistry An Asian Journal, 2022, 17
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Domino Nitro Reduction-Friedländer Heterocyclization for the Preparation of Quinolines

Kwabena Fobi and Richard A. Bunce

Molecules, 2022, 27, 4123
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From Infection to Tumor: Exploring the Therapeutic Potential of Ciprofloxacin Derivatives as Anticancer Agents

Hesham M. Hassan, Roket Hassan, Ranya Mohammed Elmagzoub, Ahmed Al-Emam, Konstantinos Kossenas, Ahmed S. Abdel-Samea, Hazim O. Khalifa, Suleyman Akocak, Stefan Bräse and Hamada Hashem

Pharmaceuticals, 2025, 18, 72
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Development of penipanoid C-inspired 2-benzoyl-1-methyl-2,3-dihydroquinazolin-4(1H)-one derivatives as potential EGFR inhibitors: Synthesis, anticancer evaluation and molecular docking study

K. Veena, M.S. Raghu, K. Yogesh Kumar, Kholood A Dahlous, Aboud Ahmed Awadh Bahajjaj, G. Mani, Byong-Hun Jeon and M.K. Prashanth

Journal of Molecular Structure, 2022, 1258, 132674
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Activation of Nrf2 signaling pathway by natural and synthetic chalcones: a therapeutic road map for oxidative stress

Melford Chuka Egbujor, Sarmistha Saha, Brigitta Buttari, Elisabetta Profumo and Luciano Saso

Expert Review of Clinical Pharmacology, 2021, 14, 465
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Molecular target interactions of quinoline derivatives as anticancer agents: A review

Vikas Pradhan, Salahuddin , Rajnish Kumar, Avijit Mazumder, Mohammad Mustaqeem Abdullah, Mohammad Shahar Yar, Mohamed Jawed Ahsan and Zabih Ullah

Chem Biol Drug Des, 2023, 101, 977
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Synthesis and biological evaluation of new quinoline‐4‐carboxylic acid‐chalcone hybrids as dihydroorotate dehydrogenase inhibitors

Milena M. Petrović, Cornelia Roschger, Kevin Lang, Andreas Zierer, Milan Mladenović, Snežana Trifunović, Boris Mandić and Milan D. Joksović

Archiv der Pharmazie, 2023, 356
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Quinoline conjugated 2-azetidinone derivatives as prospective anti-breast cancer agents: In vitro antiproliferative and anti-EGFR activities, molecular docking and in-silico drug likeliness studies

K. Govindarao, N. Srinivasan, R. Suresh, R.K. Raheja, Sivakumar Annadurai, Richie R. Bhandare and Afzal B. Shaik

Journal of Saudi Chemical Society, 2022, 26, 101471
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Bioactive nutraceuticals as G4 stabilizers: potential cancer prevention and therapy—a critical review

Satabdi Datta Choudhury, Prateek Kumar and Diptiman Choudhury

Naunyn-Schmiedeberg's Arch Pharmacol, 2024, 397, 3585
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In Vitro and In Silico Evaluation of Antiproliferative Activity of New Isoxazolidine Derivatives Targeting EGFR: Design, Synthesis, Cell Cycle Analysis, and Apoptotic Inducers

Fahad Alminderej, Siwar Ghannay, Mohamed Elsamani, Fahad Alhawday, Abuzar Albadri, Serag Elbehairi, Mohammad Alfaifi, Adel Kadri and Kaïss Aouadi

Pharmaceuticals, 2023, 16, 1025
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Investigation of new 1,2,3-triazolyl-quinolinyl-propan-2-ol derivatives as potential antimicrobial agents: in vitro and in silico approach

Abhijit D. Shinde, Yogesh M. Nandurkar, Swapnil Bhalekar, Yogesh S. Walunj, Sandip Ugale, Iqrar Ahmad, Harun Patel, Abhijit P. Chavan and Pravin C. Mhaske

Journal of Biomolecular Structure and Dynamics, 2024, 42, 1191
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Crystal Structure, Hirshfeld Surface Analysis, and Computational Study of Quinolin-8-yl 4-Chlorobenzoate: Insights from Spectroscopic, Thermal, and Antitumor Properties

Juan-Carlos Castillo, Diana Becerra and Mario A. Macías

Crystals, 2023, 13, 694
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Synthesis and Evaluation of New Phytotoxic Fluorinated Chalcones as Photosystem II and Seedling Growth Inhibitors

Geilly Mara Silva de Pádua, Taciane Santos Pitteri, Marcelo Augusto Ferreira Basso, Leonardo Gomes de Vasconcelos, Akbar Ali, Evandro Luiz Dall'Oglio, Olívia Moreira Sampaio and Lucas Campos Curcino Vieira

Chemistry & Biodiversity, 2024, 21
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Anticancer Activity of Azo Compounds (Mini-Review)

N. O. Sonin and D. M. Egorov

Russ J Gen Chem, 2024, 94, 2207
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Design, synthesis and biological evaluation of novel curcumin-fluorouracil hybrids as potential anti-cancer agents

Xiaotong Wang, Xin Li, Xu Zhang, Xuekun Wang, Jie Yang and Guoyun Liu

Biochemical Pharmacology, 2024, 230, 116559
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Unveiling ortho-phenolic Mannich ciprofloxacin-chalcone conjugates with potential antineoplastic activity: synthesis, mechanistic study, in silico docking and molecular dynamic simulation

Islam M. Abdel-Rahman, Mohamed Abdel-Aziz, Heba Ali Hassan, Dalia H. Abu-Baih, Mohamed badr, Moustafa Fathy, Ibrahim M. Salem, Tarek S. Ibrahim, Alaa M. Hayallah and GamalEl-Din A. Abuo-Rahma

European Journal of Medicinal Chemistry, 2025, 296, 117891
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Nucleophilic reactions with the novel 7-(chromon-3-yl)quinolino [3′,4′:5,6] pyrano[3,2-c]quinoline: Synthesis, biological and computational studies

Aya Ahmed, Magdy A. Ibrahim and Al-Shimaa Badran

Journal of Molecular Structure, 2023, 1292, 136120
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Promising Non-cytotoxic Monosubstituted Chalcones to Target Monoamine Oxidase-B

Luca G. Iacovino, Luca Pinzi, Giorgio Facchetti, Beatrice Bortolini, Michael S. Christodoulou, Claudia Binda, Giulio Rastelli, Isabella Rimoldi, Daniele Passarella, Maria Luisa Di Paolo and Lisa Dalla Via

ACS Med. Chem. Lett., 2021, 12, 1151
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Ring opening ring closure reactions with 5,9-diethyl-7-(chromon-3-yl)-7-hydroquinolino[3′,4′:5,6]pyrano[3,2-c]quinoline-6,8(5H,9H)-dione with some 1,2-binucleophiles: Synthesis, characterization, DFT study and biological activity

Al-Shimaa Badran, Aya Ahmed, Asmaa I. Nabeel and Magdy A. Ibrahim

Journal of Molecular Structure, 2024, 1298, 137030
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Integration of In-vivo screening, molecular docking, and molecular dynamics simulations for studying the antiepileptic potential of newly synthesized 5-naphthalen-1-yl-5,10-dihydro-1H-pyrimido[4,5-b]quinoline-2,4-diones in optimized reaction conditions by utilizing -proline as green catalyst

Rajnish Kumar, Himanshu Singh, Abhijit Debnath, Salahuddin, Avijit Mazumder, N. Bano, Virat Khanna, Sorabh Lakhanpal, Manikonda Srinivasa Sesha Sai, Ganesh Bushi, Shilpa Gaidhane, Pankaj Kumar Tyagi and Bhupinder Kapoor

Journal of Molecular Structure, 2025, 1324, 140814
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Novel chalcone/aryl carboximidamide hybrids as potent anti-inflammatory via inhibition of prostaglandin E2 and inducible NO synthase activities: design, synthesis, molecular docking studies and ADMET prediction

Tarek S. Ibrahim, Amr H. Moustafa, Ahmad J. Almalki, Rasha M. Allam, Abdulhamid Althagafi, Shadab Md and Mamdouh F. A. Mohamed

Journal of Enzyme Inhibition and Medicinal Chemistry, 2021, 36, 1067
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Synthesis and in vitro Antiproliferative Evaluation and Molecular Docking Studies of Novel Chalcone‐Phosphonates Derivatives as Anticancer Agents

Shweta Mishra, Ekta Verma, Biplab Debnath, Amit Chawla, Prasanna Shama Khandige, Bhagawati Saxena, Nityananda Sahoo and Pradeep Jana

ChemistrySelect, 2024, 9
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Synthesis, Characterization of α-Cyanochalcone Compounds and Determination of Their Antibacterial, Antifungal and Antioxidant Activities

Hakan Aslan and Cumhur Avşar

ADYU J SCI, 2025, 15, 1
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Efficacy of graphene quantum dot-hyaluronic acid nanocomposites containing quinoline for target therapy against cancer cells

Mozhgan Soltani, Negar Ahmadzadeh, Sarah Rajabi, Nazanin Besharati, Niloufar Khatamian and Masoud Homayouni Tabrizi

Sci Rep, 2025, 15
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Design, synthesis, docking, DFT, and MD simulation studies of new piperazine, 1,3,4-oxadiazole, and quinoline conjugates: A search for potent antiepileptic agents

Shrishti Tripathi, Rajnish Kumar, Abhijit Debnath, Himanshu Singh, Ranjeet Kumar Yadav and Salahuddin

Bioorganic Chemistry, 2025, 162, 108595
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Synthesis, characterization, photophysical and thermal properties of cyclotriphosphazene compounds containing N-heterocyclic fluorophores

Duygu Palabıyık and Serap Beşli

Inorganica Chimica Acta, 2025, 583, 122682
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Quinoline and Analogs: Insight into the Synthesis, Biological Activity, Structure-Activity Relationship, and Interaction with Targets

Upendra Kumar, Rajnish Kumar, Avijit Mazumder, Salahuddin, Himanshu Singh, Ranjit Kumar Yadav and Greesh Kumar

MROC, 2024, 21, 862
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Pyridine-based chalcones as promising anticancer agents: Design, synthesis and in silico studies

Sharad S. Sankhe and Vilas M. Mukadam

Results in Chemistry, 2024, 9, 101633
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A Review of Natural and Synthetic Chalcones as Anticancer Agents Targeting Topoisomerase Enzymes

François-Xavier Toublet, Aurélie Laurent and Christelle Pouget

Molecules, 2025, 30, 2498
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Quinolone Derivatives as Anticancer Agents: Importance in Medicinal Chemistry

Nursyuhada Azzman, Sirajudheen Anwar, Wan Ahmad Syazani Mohamed and Nafees Ahemad

CTMC, 2024, 24, 1134
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Michael Acceptors as Anti-Cancer Compounds: Coincidence or Causality?

Celia María Curieses Andrés, José Manuel Pérez de la Lastra, Elena Bustamante Munguira, Celia Andrés Juan and Eduardo Pérez-Lebeña

IJMS, 2024, 25, 6099
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Catalyst-free synthesis of highly functionalized triazole hexahydroquinoline carbohydrazide scaffolds via four-component cyclocondensation reaction

Hasti Amorzesh, Mohammad Bayat and Shima Nasri

Mol Divers, 2024, 28, 51
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The Versatile Quinoline and Its Derivatives as anti-Cancer Agents: An Overview

Basavarajaiah Suliphuldevara Mathada

Polycyclic Aromatic Compounds, 2023, 43, 4333
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Synthesis, Antimicrobial Activities, and Molecular Modeling Studies of Agents for the Sortase A Enzyme

Gizem Tatar Yilmaz, Nurettin Yayli, Tamer Tüzüner, Gözde Bozdal, Merve Salmanli, Gülin Renda, Büşra Korkmaz, Arif Bozdeveci and Şengül Alpay Karaoğlu

Chemistry & Biodiversity, 2024, 21
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Synthesis, in vitro potency of inhibition, enzyme kinetics and in silico studies of quinoline-based α-glucosidase inhibitors

Minoo Khalili Ghomi, Navid Dastyafteh, Mohammad Nazari Montazer, Milad Noori, Somayeh Mojtabavi, Mohammad Ali Faramarzi, Seyedeh Mahdieh Hashemi and Mohammad Mahdavi

Sci Rep, 2024, 14
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Novel styryl-heterocyclic hybrids: Synthesis, characterization and anticancer activity

Lamya A. Al-lehaib, Ehab M.M. Ali, Khalid O. Al-Footy and Reda M. El-Shishtawy

Results in Chemistry, 2024, 7, 101374
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Quinoline-hydrazone Conjugates: Recent Insights into Synthetic Strategies, Structure-activity Relationship, and Biological Activities

Upendra Kumar, Rajnish Kumar, Avijit Mazumder, Salahuddin and Greesh Kumar

LDDD, 2024, 21, 2853
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Hydroxamic Acids Containing a Bicyclic Pinane Backbone as Epigenetic and Metabolic Regulators: Synergizing Agents to Overcome Cisplatin Resistance

Yulia Aleksandrova, Aldar Munkuev, Evgenii Mozhaitsev, Evgeniy Suslov, Konstantin Volcho, Nariman Salakhutdinov and Margarita Neganova

Cancers, 2023, 15, 4985
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Novel chalcone candidates as potential in vitro and in vivo anti-inflammatory agents: Synthesis, in silico docking, multitarget bioevaluation and molecular dynamic simulation

Alshimaa Kh.M. Ahmed, Eman A.M. Beshr, Ibrahim M. Salem, Osama A.A. Ahmed, Tarek S. Ibrahim, Deiaa E. Elsayed Abouzed, Ahmed Mostafa Mahmoud and Mamdouh F.A. Mohamed

Bioorganic Chemistry, 2025, 161, 108540
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Sulphur Containing Heterocyclic Compounds as Anticancer Agents

Balwinder Kaur, Gurdeep Singh, Vikas Sharma and Iqubal Singh

ACAMC, 2023, 23, 869
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A review on innovative approaches in quinoline/isoquinoline synthesis: Unveiling the Pummerer reaction strategy

Tanvi Rajiv Goel, Salahuddin, Kavita Rana, Avijit Mazumder, Rajnish Kumar, Mohamed Jawed Ahsan, Mohammad Shahar Yar, Pankaj Kumar Tyagi and Saurabh Singh

Synthetic Communications, 2024, 54, 2089
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Synthesis Quinoline Derivative via Green Chemistry Approach and Its Characterization

Amita Vyas, Parth Manvar, Dharmesh Katariya and Ranjan Khunt

SSRN Journal, 2024
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Synthesis, photophysical and photochemical properties of unsymmetrical zinc(II) phthalocyanines bearing 8-hydroxyquinoline unit

Erem Ahmetali, Burak Yıldız, Elçin Ezgi Ahi, Mahmut Durmuş and M. Kasım Şener

Polyhedron, 2022, 226, 116111
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One-Pot Sequential Synthesis of Alkenylated Dihydroquinolinones and Hexahydroacridinones in Deep Eutectic Solvent Medium

Sundararajan Suresh and Fazlur Rahman Nawaz Khan

ACS Omega, 2024
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Therapeutic Potental of Quinolin-2H-one Hybrids as Anticancer Agents

Naik Soniya, Vasu Soumya, Mamle Desai Shivlingrao, Manickavasagam M. and Chellappan Meeramol

MRMC, 2025, 25, 386
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A quinoline derivative exerts antineoplastic efficacy against solid tumour by inducing apoptosis and anti-angiogenesis both in vitro and in vivo

Pradeepa Kumar C, Banumathi, N. D. Satyanarayan, Sakshith Raghavendra Prasad, Rajeshwara N. Achur and B. T. Prabhakar

Naunyn-Schmiedeberg's Arch Pharmacol, 2025, 398, 9161
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Nickel‐Catalyzed Sequential Synthesis of Alkylated Quinolines and Their Photophysical Studies

Pari Keerthana and Fazlur Rahman Nawaz Khan

Asian J Org Chem, 2024
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Design, synthesis, and molecular docking of novel pyrazole-chalcone analogs of lonazolac as 5-LOX, iNOS and tubulin polymerization inhibitors with potential anticancer and anti-inflammatory activities

Asmaa H.H. Ahmed, Mamdouh F.A. Mohamed, Rasha M. Allam, Ayman Nafady, Shaaban K. Mohamed, Ahmed E. Gouda and Eman A.M. Beshr

Bioorganic Chemistry, 2022, 129, 106171
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Synthesis, Photophysical Properties, Theoretical Studies, and Living Cancer Cell Imaging Applications of New 7-(Diethylamino)quinolone Chalcones

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A three-step pathway from (2-aminophenyl)chalcones to novel styrylquinoline–chalcone hybrids: synthesis and spectroscopic and structural characterization of three examples

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A tandem approach for the synthesis of 1-phenyl-pyrazolo-quinolinones by Fe 3 O 4 @MWCNT nanocomposite as heterogeneous catalyst

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Design, synthesis, and biological evaluation of novel quinoline derivatives as small molecule mutant EGFR inhibitors targeting resistance in NSCLC: In vitro screening and ADME predictions

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Design, Synthesis, and Anti-Breast Cancer Potential of Imidazole–Pyridine Hybrid Molecules In Vitro and Ehrlich Ascites Carcinoma Growth Inhibitory Activity Assessment In Vivo

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ACS Omega, 2023, 8, 40287
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Design and Synthesis of Some New Quinoline-thiazolidine-2,4-dione-isoxazole Conjugates as EGFR Targeting Agents

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In vitro cytotoxicity and docking study of novel symmetric and asymmetric dihydropyridines and pyridines as EGFR tyrosine kinase inhibitors

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Design, synthesis and antitumor activity of potent and safe para-quinone methides derivatives in vitro and in vivo

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Novel quinoline-4-carboxamide derivatives potentiates apoptosis by targeting PDK1 to overcome chemo-resistance in colorectal cancer: Theoretical and experimental results

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An Efficient Synthesis in Water of Novel Oxoquinolines and Their Anticancer Activities

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Medicinally Privileged Natural Chalcones: Abundance, Mechanisms of Action, and Clinical Trials

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A multifaceted approach to novel (E)-3-(4-bromobenzylidene)-1,8-naphthyridine-2,4(1H,3H)-dione: synthesis, biological screening, DFT and molecular docking studies

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Synthesis, design, and antimicrobial activity of pyrido[2,3‐d][1,2,4]triazolo[4,3‐a]pyrimidinones based on quinoline derivatives

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Chalcone Derivative Induces Flagellar Disruption and Autophagic Phenotype in Phytomonas serpens In Vitro

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