Themed collection Recent Review Articles
Mast cell-derived exosomes and claudin regulation in ulcerative colitis: emerging insights and therapeutic potential
Ulcerative colitis (UC) is a chronic inflammatory condition marked by immune dysfunction and disruption of the intestinal epithelial barrier, in which mast cells play a significant role through the release of inflammatory mediators.
Nanoscale Adv., 2025,7, 6774-6785
https://doi.org/10.1039/D5NA00707K
The emerging role of semiconductor nano-photocatalysts in strengthening surface enhanced Raman scattering applicability for sustainable multifunctional applications
The work establishes sustainable next-generation SERS platforms based on semiconductor nano-photocatalysts that offer enhanced durability and multifunctionality beyond traditional noble metal systems.
Nanoscale Adv., 2025,7, 6394-6411
https://doi.org/10.1039/D5NA00597C
Progress on quantum transport engineering in atomically precise anisotropic nanoporous graphene
Here we review recent progress on atomically-precise anisotropic nanoporous graphenes (aNPGs) and their predicted highly tunable quantum transport anisotropy.
Nanoscale Adv., 2025,7, 5932-5943
https://doi.org/10.1039/D5NA00532A
Recent progress in the synthesis of nanostructured Ti3C2Tx MXene for energy storage and wastewater treatment: a review
MXene-based functional 2D materials hold significant potential for addressing global challenges related to energy and water crises.
Nanoscale Adv., 2025,7, 3999-4017
https://doi.org/10.1039/D5NA00021A
Unlocking a radioactive pertechnetate (TcO4−) treatment process with functionalized metal–organic frameworks (MOFs)
This review highlights the latest advancements in the use of metal–organic frameworks (MOFs) to efficiently separate TcO4− ions. It explores the mechanisms and receptor chemistry involved in TcO4− ion capture for selective targeting.
Nanoscale Adv., 2025,7, 984-1008
https://doi.org/10.1039/D4NA00779D
FLASH radiotherapy: mechanisms, nanotherapeutic strategy and future development
Ultra-high dose-rate (FLASH) radiotherapy serves as an ideal procedure to treat tumors efficiently without harming normal tissues and has demonstrated satisfactory antitumor effects in multiple animal tumor models.
Nanoscale Adv., 2025,7, 711-721
https://doi.org/10.1039/D4NA00753K
Metallic nanoparticles: from biosynthesis to biomedical applications, current scenario and prospects
Nanoscale Adv., 2026, Accepted Manuscript
https://doi.org/10.1039/D4NA01054J
Progress in the application of conductive hydrogel in wound healing: A review
Nanoscale Adv., 2026, Accepted Manuscript
https://doi.org/10.1039/D5NA00650C
Hybrid nanoencapsulation systems: integrating natural polymers with synthetic nanomaterials for enhanced delivery of bioactive compounds in functional foods
This review uniquely focuses on food polymer-based hybrid nanocarriers for precise and targeted delivery of functional bioactive compounds.
Nanoscale Adv., 2025,7, 7867-7890
https://doi.org/10.1039/D5NA00751H
Application of nanomaterials in organoid culture and cryopreservation
Organoids are invaluable models for studying organ development, disease mechanism modelling, drug screening, and regenerative medicine.
Nanoscale Adv., 2025,7, 7483-7503
https://doi.org/10.1039/D5NA00534E
Recent advances in biological, photocatalytic and adsorption applications of biosynthesized CeO2 nanoparticles
Herein, the plant extract-mediated synthesis and applications of CeO2 nanoparticles were reviewed. Biosynthesized CeO2 and their composites exhibited a wide range of biomedical and environmental applications.
Nanoscale Adv., 2025,7, 7459-7482
https://doi.org/10.1039/D5NA00876J
Responsible innovation in nanotechnology: response to grand societal challenges
This study offers a distinctive integration of how responsible nanotechnology innovation tackles various major societal issues across a wide range of application areas.
Nanoscale Adv., 2025,7, 7424-7439
https://doi.org/10.1039/D5NA00586H
Recent advances in gold nanoparticle-based targeted photodynamic and photothermal cancer therapy
Gold nanoparticle-based targeted PDT and PTT.
Nanoscale Adv., 2025,7, 7440-7458
https://doi.org/10.1039/D5NA00767D
Interfacial engineering of nano-copper: mechanisms, strategies, and innovations for oxidation resistance
Nano-copper, characterized by its unique physicochemical properties such as high specific surface area, quantum size effects, and exceptional conductivity, has emerged as a pivotal material in advanced technologies.
Nanoscale Adv., 2025,7, 7109-7127
https://doi.org/10.1039/D5NA00716J
Surface-enhanced Raman spectroscopy as a tool for food and environmental monitoring of pesticides: recent trends and perspectives
Recent advances in nanomaterials have enhanced SERS sensitivity and selectivity for pesticide detection in complex food and environmental matrices.
Nanoscale Adv., 2025,7, 7061-7085
https://doi.org/10.1039/D5NA00539F
Nanomedicine revolutionizing cancer immunotherapy: recent advancements in nanotechnological strategies and applications
The convergence of nanotechnology and cancer immunotherapy represents a promising frontier in the fight against cancer, offering new avenues for enhancing therapeutic efficacy and precise personalized cancer treatments.
Nanoscale Adv., 2025,7, 7086-7108
https://doi.org/10.1039/D5NA00390C
Fourier transform infrared spectroscopic technique for analysis of inorganic materials: a review
FTIR is a very important analytical technique that is widely used for the detection and analysis of inorganic materials.
Nanoscale Adv., 2025,7, 6677-6702
https://doi.org/10.1039/D5NA00522A
Novel advancements in nanomaterials-based contrast agents across multimodal imaging and theranostic applications
Schematic illustration of theranostic nanoparticle (NP)-based contrast agents for multimodal imaging, depicting major NP categories used across different imaging modalities and disease-specific theranostics.
Nanoscale Adv., 2025,7, 6753-6773
https://doi.org/10.1039/D5NA00596E
Magnetic catalyst marvels: a sustainable approach to highly substituted imidazole synthesis
This comprehensive review delves into the recent advancements in magnetic catalyst technology, mainly focusing on their application in facilitating greener and more efficient synthetic routes for imidazole derivatives.
Nanoscale Adv., 2025,7, 6703-6752
https://doi.org/10.1039/D5NA00368G
Advances in the chemical analysis of nitrite in environmental and biological samples
A comprehensive overview of advanced instrumental methods for nitrite detection, illustrating their interconnections and diverse applications. This review explores trends and advances in instrumental analysis for nitrite detection.
Nanoscale Adv., 2025,7, 6321-6372
https://doi.org/10.1039/D5NA00503E
Research advances in SERS-based sensing platforms for multiplex mycotoxin detection in feed
This comprehensive review summarizes the application of various SERS substrates in the detection of mycotoxins in feed and provides an outlook on the future development of SERS technology in the field of feed detection.
Nanoscale Adv., 2025,7, 6308-6320
https://doi.org/10.1039/D5NA00394F
Self-organization of photonic structures in colloidal crystals in the AI era
The advent of smart-engineered photonic materials, a development primarily influenced by the cutting-edge technology of artificial intelligence (AI), has ushered in a new era of unprecedented control over the manipulation and propagation of light.
Nanoscale Adv., 2025,7, 6373-6393
https://doi.org/10.1039/D5NA00449G
Advances in nanomechanical property mapping by atomic force microscopy
AFM-based mechanical property measurements are widely used in energy storage, polymer science, mechanobiology or nanomedicine.
Nanoscale Adv., 2025,7, 6286-6307
https://doi.org/10.1039/D5NA00702J
Antibody-functionalized lipid nanocarriers for RNA-based cancer gene therapy: advances and challenges in targeted delivery
Despite remarkable advances in cancer therapeutics, conventional treatments still face significant hurdles, including systemic toxicity, poor tumor specificity, multidrug resistance, and suboptimal intracellular delivery.
Nanoscale Adv., 2025,7, 5905-5931
https://doi.org/10.1039/D5NA00323G
Nanomedicine breakthroughs overcoming pancreatic cancer drug resistance through precision nano-interventions
Stimuli-responsive nanocarriers tailored to bypass efflux pumps, target cancer stem cells, and remodel the stroma overcome PDAC resistance and enhance therapeutic efficacy.
Nanoscale Adv., 2025,7, 5888-5904
https://doi.org/10.1039/D5NA00513B
Impact of nanofillers on vitrimerization and recycling strategies: a review
Innovative recycling of polymer nanocomposites enabled by vitrimerization, highlighting the role of nanofillers in enhancing network dynamics, recyclability, mechanical strength, and sustainable material lifecycles.
Nanoscale Adv., 2025,7, 5842-5887
https://doi.org/10.1039/D5NA00183H
The synergy of metal–organic frameworks and biomaterials for bone tissue engineering: recent advances, challenges, and future recommendations
This review provides an overview of recent progress, challenges, and future directions in the application of MOFs and MOF-based composites for bone tissue engineering.
Nanoscale Adv., 2025,7, 5479-5500
https://doi.org/10.1039/D5NA00279F
Green synthesis of metallic nanoparticles using Pistacia species: improved stability and biological activities
This review highlights the promise of Pistacia-derived metallic nanoparticles in biomedical applications, while emphasizing mechanistic, toxicological, and stability considerations crucial for clinical translation.
Nanoscale Adv., 2025,7, 5449-5478
https://doi.org/10.1039/D5NA00644A
Effects of different types of modifiers on structural variation of nano-hydroxyapatite for efficient application
Structural modification of hydroxyapatites for fruitful applications in various fields.
Nanoscale Adv., 2025,7, 5133-5160
https://doi.org/10.1039/D5NA00392J
The evolution of integrated magnetic hyperthermia and chemodynamic therapy for combating cancer: a comprehensive viewpoint
MHT–CDT therapy synergistically induces mitochondrial damage via thermal stress and promotes tumor ablation via Fenton reactions. Critical considerations include clinical translation, cost-efficiency, resistance, ethics, and personalized approaches.
Nanoscale Adv., 2025,7, 4820-4836
https://doi.org/10.1039/D4NA01004C
Nano-enhanced Fenton/Fenton-like chemistry: integrating peroxidase nanozymes, MOFs, and MXenes for next-generation colorimetric biosensors
This review first describes mechanisms of Fenton/Fenton-like reaction for colorimetric detection; then, recent advances in developing Fenton/Fenton-like reaction assisted by nanotechnology as well as nanomaterials are discussed.
Nanoscale Adv., 2025,7, 4763-4779
https://doi.org/10.1039/D5NA00387C
Recent advances in graphitic carbon nitride-based composites for enhanced photocatalytic degradation of rhodamine B: mechanism, properties and environmental applications
This review explores g-C3N4 modifications to boost photocatalysis for rhodamine B degradation, analyzing key factors, reactive oxygen species and charge transfer mechanisms, and environmental applications, challenges, prospects.
Nanoscale Adv., 2025,7, 4780-4802
https://doi.org/10.1039/D5NA00439J
Electron spin resonance with scanning tunneling microscopy: a tool for an on-surface quantum platform of identical qubits
An on-surface quantum platform of identical spin qubits, made of three titanium atoms on an ultrathin magnesium oxide layer with atomic scale precision.
Nanoscale Adv., 2025,7, 4551-4558
https://doi.org/10.1039/D5NA00316D
Electromagnetic interference shielding: a comprehensive review of materials, mechanisms, and applications
Rapid advancements in nanotechnology have led to electronic devices with densely integrated components, contributing to increased Electromagnetic Interference (EMI) pollution.
Nanoscale Adv., 2025,7, 4510-4534
https://doi.org/10.1039/D5NA00240K
A review of interface optimization strategies for solid electrolytes and anode materials
This paper reviews classifications and properties of solid electrolytes and anode materials, focusing on interface issues with Li metal and Si-based anodes, and proposes solutions with current research advances.
Nanoscale Adv., 2025,7, 4535-4550
https://doi.org/10.1039/D5NA00286A
Impact of ion intercalation materials on advancing capacitive deionization: from theory to practical
Figure highlights the synthesizing strategies, properties, applications, advantages and strength of ion intercalation materials by understanding their different behaviour.
Nanoscale Adv., 2025,7, 4270-4292
https://doi.org/10.1039/D5NA00311C
A comprehensive analysis of nanomagnetism models for the evaluation of particle energy in magnetic hyperthermia
Magnetic nanoparticles have attracted significant research interest due to their unique magnetic properties, which differ from their bulk counterparts and enable applications in information technology, environmental protection, and biomedicine.
Nanoscale Adv., 2025,7, 4252-4269
https://doi.org/10.1039/D5NA00258C
Future development directions of high-temperature strain gauges: a comprehensive review of structure and performance characteristics
High-temperature strain gauges have garnered significant interest from researchers due to their high precision, exceptional temperature tolerance, and robust anti-interference capabilities.
Nanoscale Adv., 2025,7, 4232-4251
https://doi.org/10.1039/D5NA00039D
Synthesis methods, structure, and recent trends of ZIF-8-based materials in the biomedical field
ZIF-8 offers exceptional structural properties and high drug-loading capacities beneficial for drug delivery systems. Herein, the synthesis methods and multifunctional applications of ZIF-8-based biomaterials in biomedical engineering are discussed.
Nanoscale Adv., 2025,7, 3941-3960
https://doi.org/10.1039/D4NA01015A
Carbon quantum dots for sustainable energy: enhancing electrocatalytic reactions through structural innovation
A comprehensive review highlights the electrocatalytic roles of carbon quantum dots in key energy-related reactions including the OER, the HER, the ORR, the CO2RR, liquid fuel electrooxidation, and bifunctional catalysis.
Nanoscale Adv., 2025,7, 3961-3998
https://doi.org/10.1039/D5NA00205B
Application of the synergism between eggshells and copper in nanotechnology
Intriguing synergism between eggshell and Cu for versatile applications.
Nanoscale Adv., 2025,7, 3914-3940
https://doi.org/10.1039/D5NA00400D
Graphene's Frontier in aerospace: current applications, challenges, and future directions for space engineering
Graphene is suitable for aerospace and space engineering because its single carbon layer exhibits excellent mechanical, electrical and thermal characteristics.
Nanoscale Adv., 2025,7, 3603-3618
https://doi.org/10.1039/D4NA00934G
A review of emerging trends in nanomaterial-driven AI for biomedical applications
There is a significant chance that the convergence of AI and nanotechnology will affect numerous other scientific domains.
Nanoscale Adv., 2025,7, 3619-3630
https://doi.org/10.1039/D5NA00032G
Unique advantages and applications of polysaccharide microneedles as drug delivery materials and in treatment of skin diseases
Owing to its non-invasive nature, painless drug delivery, and controlled drug loading capacity, the microneedle (MN) technology has recently garnered significant attention in clinical practice.
Nanoscale Adv., 2025,7, 3631-3654
https://doi.org/10.1039/D4NA01083C
Reactive oxygen species-dependent nanomedicine therapeutic modalities for gastric cancer
ROS play a double-edged role in gastric cancer. Based on their functions, nano-delivery systems taking the therapeutic advantages of ROS have been widely employed in recent years, overcoming the drawbacks of conventional drug delivery techniques.
Nanoscale Adv., 2025,7, 3210-3227
https://doi.org/10.1039/D5NA00321K
Bimetallic nanoparticles as pioneering eco-friendly catalysts for remediation of pharmaceuticals and personal care products (PPCPs)
PPCPs in water pose environmental and health risks, with conventional treatments often prove inadequate. Bimetallic nanoparticles offer a green, efficient alternative. This review highlights their synthesis, properties, and role in PPCP degradation.
Nanoscale Adv., 2025,7, 3160-3188
https://doi.org/10.1039/D5NA00151J
A comprehensive review on carbonylation reactions: catalysis by magnetic nanoparticle-supported transition metals
Magnetic catalysts have become a crucial innovation in carbonylation reactions, providing a sustainable and highly efficient means of synthesizing compounds that contain carbonyl groups.
Nanoscale Adv., 2025,7, 3189-3209
https://doi.org/10.1039/D5NA00040H
Advancements in molecular imaging for the diagnosis and treatment of pancreatic ductal adenocarcinoma
Application of molecular imaging techniques for diagnosis and treatment of PDAC.
Nanoscale Adv., 2025,7, 2887-2903
https://doi.org/10.1039/D4NA01080A
Advances in core technologies for semiconductor manufacturing: applications and challenges of atomic layer etching, neutral beam etching and atomic layer deposition
Revolutionizing semiconductor fabrication, ALD, ALE, and NBE deliver atomic-scale precision, driving unprecedented performance and scalability in next-generation miniaturized devices.
Nanoscale Adv., 2025,7, 2796-2817
https://doi.org/10.1039/D4NA00784K
Biotransformation and biological fate of magnetic iron oxide nanoparticles for biomedical research and clinical applications
Safe implementation of nanotechnology-based products in biomedical applications necessitates an extensive understanding of the (bio)transformations that nanoparticles undergo in living organisms.
Nanoscale Adv., 2025,7, 2818-2886
https://doi.org/10.1039/D5NA00195A
Biotechnology-assisted cancer therapy using metal sulfides based on their optical and thermophysical properties
This review provides a comprehensive introduction to 2D-TMSs, including their nanostructures, performance, and applications in drug delivery, photothermal therapy, sonodynamic therapy, and ferroptosis.
Nanoscale Adv., 2025,7, 2773-2795
https://doi.org/10.1039/D4NA00929K
Plant extract-mediated green-synthesized CuO nanoparticles for environmental and microbial remediation: a review covering basic understandings to mechanistic study
Environmental and microbial remediations using green-synthesized CuO nanoparticles from plant extracts.
Nanoscale Adv., 2025,7, 2418-2445
https://doi.org/10.1039/D5NA00035A
A review on the green synthesis of metal (Ag, Cu, and Au) and metal oxide (ZnO, MgO, Co3O4, and TiO2) nanoparticles using plant extracts for developing antimicrobial properties
Green synthesis using plant extract is used to tune the antimicrobial property of metals and metal oxides nanoparticles.
Nanoscale Adv., 2025,7, 2446-2473
https://doi.org/10.1039/D5NA00037H
Research progress on the epitaxial growth of hexagonal boron nitride on different substrates by the CVD method
This article details the synthesis methodologies and research progress of h-BN epitaxial growth on solid transition metal, liquid metal, alloy, sapphire/metal and semiconductor substrates.
Nanoscale Adv., 2025,7, 2395-2417
https://doi.org/10.1039/D4NA00477A
A comprehensive review on nano-fertilizers: preparation, development, utilization, and prospects for sustainable agriculture in Ethiopia
Nano-fertilizers enhance crop yield and soil health by improving nutrient absorption and minimizing environmental impact. This review explores their formulation, application methods, and potential for sustainable agriculture in Ethiopia.
Nanoscale Adv., 2025,7, 2131-2144
https://doi.org/10.1039/D4NA01068J
Advances in RNAi-based nanoformulations: revolutionizing crop protection and stress tolerance in agriculture
Nucleic acid-based therapeutics have the ability to tackle a wide range of diseases and stress tolerance that present significant obstacles for conventional approaches in agriculture.
Nanoscale Adv., 2025,7, 1768-1783
https://doi.org/10.1039/D5NA00044K
Emerging engineered nanozymes: current status and future perspectives in cancer treatments
Nanozymes with multiple catalytic activities for cancer treatment are summarized, and their performances when combined with various cancer treatments or used alone are compared.
Nanoscale Adv., 2025,7, 1226-1242
https://doi.org/10.1039/D4NA00924J
Structure–activity relationships in the development of single atom catalysts for sustainable organic transformations
Exploration of single atom catalysts for unmatched efficiency and selectivity in organic transformations through morphological control and metal–support interactions.
Nanoscale Adv., 2025,7, 1243-1271
https://doi.org/10.1039/D4NA00433G
Extracellular vesicles: from intracellular trafficking molecules to fully fortified delivery vehicles for cancer therapeutics
Extracellular vesicles (EVs) are emerging tools in cancer diagnosis, prognosis and therapeutics.
Nanoscale Adv., 2025,7, 934-962
https://doi.org/10.1039/D4NA00393D
An overview of the use of non-titanium MXenes for photothermal therapy and their combinatorial approaches for cancer treatment
This comprehensive review provides a concise overview of the current research patterns, properties, and biomedical applications of non-Ti MXenes, particularly in photothermal therapy and its combinatorial approaches.
Nanoscale Adv., 2025,7, 963-983
https://doi.org/10.1039/D4NA00931B
Efficient counter electrode for quantum dot sensitized solar cells using p-type PbS@reduced graphene oxide composite
This study developed a novel PbS–rGO composite counter electrode to enhance the performance of quantum dot-sensitized solar cells (QDSSCs).
Nanoscale Adv., 2025,7, 700-710
https://doi.org/10.1039/D4NA00971A
Advanced mechanisms and applications of microwave-assisted synthesis of carbon-based materials: a brief review
This review explores microwave interaction with carbon materials, focusing on heat generation, plasma excitation, reactor design, and applications, along with challenges and future prospects for synthesis in lab and industry.
Nanoscale Adv., 2025,7, 419-432
https://doi.org/10.1039/D4NA00701H
Recent advances in irradiation-mediated synthesis and tailoring of inorganic nanomaterials for photo-/electrocatalysis
In this review, the mechanisms and applications of radiation technology in the development of inorganic photo-/electrocatalysts are summarized, and its recent research progress, challenges, and future development prospects are further explored.
Nanoscale Adv., 2025,7, 384-418
https://doi.org/10.1039/D4NA00806E