Issue 1, 2022

Cp*Rh(iii)/boron hybrid catalysis for directed C–H addition to β-substituted α,β-unsaturated carboxylic acids

Abstract

The C–H bond addition reaction of 2-phenylpyridine derivatives with α,β-unsaturated carboxylic acids catalyzed by Cp*Rh(III)/BH3·SMe2 is reported. Activation of C–H bonds with the rhodium catalyst and activation of α,β-unsaturated carboxylic acids with the boron catalyst cooperatively work, and a BINOL-urea hybrid ligand significantly improved the reactivity. With the optimized hybrid catalytic system, various β-disubstituted carboxylic acids were obtained under mild reaction conditions.

Graphical abstract: Cp*Rh(iii)/boron hybrid catalysis for directed C–H addition to β-substituted α,β-unsaturated carboxylic acids

Supplementary files

Article information

Article type
Communication
Submitted
22 Okt 2021
Accepted
29 Nov 2021
First published
29 Nov 2021

Chem. Commun., 2022,58, 76-79

Cp*Rh(III)/boron hybrid catalysis for directed C–H addition to β-substituted α,β-unsaturated carboxylic acids

R. Tanaka, Y. Hirata, M. Kojima, T. Yoshino and S. Matsunaga, Chem. Commun., 2022, 58, 76 DOI: 10.1039/D1CC05956D

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements