Issue 48, 2020

Recent developments in pre-treatment and analytical techniques for synthetic polymers by MALDI-TOF mass spectrometry

Abstract

A great deal of effort has been expended to develop accurate means of determining the properties of synthetic polymers using matrix-assisted laser desorption/ionization (MALDI) time-of-flight (TOF) mass spectrometry (MS). Many studies have focused on the importance of sample pre-treatment to obtain accurate analysis results. This review discusses the history of synthetic polymer characterization and highlights several applications of MALDI-TOF MS that recognize the importance of pre-treatment technologies. The subject area is of significance in the field of analytical chemistry, especially for users of the MALDI technique. Since the 2000s, many such technologies have been developed that feature improved methods and conditions, including solvent-free systems. In addition, the recent diversification of matrix types and the development of carbon-based matrix materials are described herein together with the current status and future directions of MALDI-TOF MS hardware and software development. We provide a summary of processes used for obtaining the best analytical results with synthetic polymeric materials using MALDI-TOF MS.

Graphical abstract: Recent developments in pre-treatment and analytical techniques for synthetic polymers by MALDI-TOF mass spectrometry

Article information

Article type
Critical Review
Submitted
11 Sep 2020
Accepted
23 Okt 2020
First published
09 Nov 2020

Anal. Methods, 2020,12, 5767-5800

Recent developments in pre-treatment and analytical techniques for synthetic polymers by MALDI-TOF mass spectrometry

H. Yoo, D. Kim, D. Shin, Y. Oh, S. Lee, J. Y. Lee, Y. Choi, S. H. Lee, K. Lee, Y. Kim and K. Cho, Anal. Methods, 2020, 12, 5767 DOI: 10.1039/D0AY01729A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements