Issue 7, 2019

Hydroaminoalkylation of sterically hindered alkenes with N,N-dimethyl anilines using a scandium catalyst

Abstract

An atom- and step-economical C(sp3)–H addition of N,N-dimethyl anilines to various sterically demanding 1,1- and 1,2-disubstituted alkenes has been achieved by using a simple β-diketiminato ligand supported scandium dialkyl complex in combination with a borate compound. The corresponding C(sp3)–C(sp3) bond forming reaction occurs with excellent regioselectivities to give a variety of tertiary aromatic amines.

Graphical abstract: Hydroaminoalkylation of sterically hindered alkenes with N,N-dimethyl anilines using a scandium catalyst

Supplementary files

Article information

Article type
Paper
Submitted
26 Okt 2018
Accepted
10 Dez 2018
First published
10 Dez 2018

Org. Biomol. Chem., 2019,17, 2013-2019

Hydroaminoalkylation of sterically hindered alkenes with N,N-dimethyl anilines using a scandium catalyst

J. Su, Y. Zhou and X. Xu, Org. Biomol. Chem., 2019, 17, 2013 DOI: 10.1039/C8OB02657B

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements