Issue 2, 2018

Evolution of two routes for asymmetric total synthesis of tetrahydroprotoberberine alkaloids

Abstract

Two synthetic routes have been developed for the asymmetric synthesis of tetrahydroprotoberberines, featuring installation of the asymmetry at an early stage of asymmetric redox-A3 reaction and the late stage of asymmetric Noyori asymmetric transfer hydrogenation, respectively. This work is filling the gap between racemic and asymmetric syntheses of tetrahydroprotoberberines enabled by redox-A3 reaction.

Graphical abstract: Evolution of two routes for asymmetric total synthesis of tetrahydroprotoberberine alkaloids

Supplementary files

Article information

Article type
Research Article
Submitted
30 Aug 2017
Accepted
30 Sep 2017
First published
09 Okt 2017

Org. Chem. Front., 2018,5, 242-246

Evolution of two routes for asymmetric total synthesis of tetrahydroprotoberberine alkaloids

J. Yu, Z. Zhang, S. Zhou, W. Zhang and R. Tong, Org. Chem. Front., 2018, 5, 242 DOI: 10.1039/C7QO00776K

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements