Malus hupehensis leaves: a functional beverage for alleviating hepatic inflammation and modulating gut microbiota in diabetic mice

Qiue Zhang, Tong Su, Yajing Pan, Xiaomeng Wang, Chengfei Zhang, Huizhao Qin, Mingxiu Li, Qingsong Li, Xiaochen Li, Jiangfan Guo, Lili Wu, Lingling Qin and Tonghua Liu

Food Funct., 2025, 16, 2972
DOI: 10.1039/D4FO05325G

Functional food lycopene mitigates obesity-related cognitive decline via lipid metabolism regulation and neuroprotection via taurine and glutathione pathway

Yuqing Wu and Jingfang Liu

Clinical Nutrition, 2025, 51, 136
DOI: 10.1016/j.clnu.2025.06.005

Mechanism of Plantamajoside in inhibiting ferroptosis of pancreatic β cells and treatment of T2DM via activation of the xCT/GPX4 pathway

Hongmin Zhao, Renlin Li, Xuan Guo, Jingrui Kang, Huajun Li, Xiaoyun Wang, Yuansong Wang, Huantian Cui, Shuquan Lv, Weibo Wen, Zhongyong Zhang and Kai Huang

PLoS One, 2025, 20, e0325674
DOI: 10.1371/journal.pone.0325674

Computational Pharmacology Analysis of Lycopene to Identify Its Targets and Biological Effects in Humans

Abhinand Rao and Arun H. S. Kumar

Applied Sciences, 2025, 15, 7815
DOI: 10.3390/app15147815

Targeting Regulation of Macrophage to Treat Metabolic Disease: Role of Phytochemicals

Zeting Ye, Yanlin Li, Xiaolin Yang, Chenglin Li, Rui Yu, Guangjuan Zheng and Zuqing Su

Cell Proliferation, 2025, 58
DOI: 10.1111/cpr.70012

Adipocyte‐specific FAK deletion promotes pancreatic β‐cell apoptosis via adipose inflammatory response to exacerbate diabetes mellitus

Fei Ding, Peng Zheng, Hong‐Ting Fang, Yuan‐Yuan Luo, Xi‐Yue Yan, Hui‐Jian Chen and You‐E Yan

Clinical & Translational Med, 2024, 14
DOI: 10.1002/ctm2.1742

A Narrative Review: The Effect and Importance of Carotenoids on Aging and Aging-Related Diseases

Elif Rabia Bakac, Ece Percin, Ayse Gunes-Bayir and Agnes Dadak

IJMS, 2023, 24, 15199
DOI: 10.3390/ijms242015199

TLR2 promotes the progression of diabetes mellitus with atherosclerosis via activating NLRP3 inflammasome and MyD88/NF-κB signaling pathway

Sisi Chen, Min Xie and Yong Liu

Sci Rep, 2025, 15
DOI: 10.1038/s41598-025-00843-4

Inflammatory signaling pathways in pancreatic β-cell: New insights into type 2 diabetes pathogenesis

Jie Chen, Shinuan Fei, Lawrence W.C. Chan, Xueting Gan, Bibo Shao, Hong Jiang, Sheng Li, Peng Kuang, Xin Liu and Sijun Yang

Pharmacological Research, 2025, 216, 107776
DOI: 10.1016/j.phrs.2025.107776

The total alkaloids of Berberidis Cortex alleviate type 2 diabetes mellitus by regulating gut microbiota, inflammation and liver gluconeogenesis

Yiwen Tao, Yujiao Zeng, Rui Zeng, Xiaoling Gou, Xianhua Zhou, Jing Zhang, Tsedien Nhamdriel and Gang Fan

Journal of Ethnopharmacology, 2025, 337, 118957
DOI: 10.1016/j.jep.2024.118957

Lycopene as a Therapeutic Agent against Aflatoxin B1-Related Toxicity: Mechanistic Insights and Future Directions

Meng Li, Shusheng Tang, Xinyan Peng, Gaurav Sharma, Shutao Yin, Zhihui Hao, Jichang Li, Jianzhong Shen and Chongshan Dai

Antioxidants, 2024, 13, 452
DOI: 10.3390/antiox13040452

Sijunzi decoction improves lipid metabolism via regulation of Wnt/β-catenin signaling pathway in diabetic mice and 3T3-L1 cells

Tianyuan Liu, Yage Liu, Hanfen Shi, Gaiyue Yue, Xuan Dai, Yueyi Zhang, Shan Wang, Jin Shen, Tianshu Xu, Jiyuan Yin, Jianglan Zhang, Yanfei Zhang, Lili Wang, Gang Zhou and Dongwei Zhang

Journal of Ethnopharmacology, 2025, 346, 119672
DOI: 10.1016/j.jep.2025.119672

Lycopene Modulates Glycerophospholipid Metabolism and Promotes N‐Acylethanolamine Production to Alleviate Obesity

Jingyu Lu, Liyang Zhou, Chang Liu and He Qian

Journal of Food Science, 2025, 90
DOI: 10.1111/1750-3841.70373

Study on the protective effect of Aronia melanocarpa extract on type 2 diabetes by regulating glucose and lipid metabolism through intestinal flora

Dan Song and Cheng Fang

Food Science & Nutrition, 2024, 12, 7620
DOI: 10.1002/fsn3.4378

miR-365-3p Regulates Gastrointestinal Dysfunction in Diabetes Mellitus Rats via the TLR4/MyD88/NF-κB Pathway

Jiao Xiao, Bin Gao, Yan Xiao and Xiangjie Liu

Molecular and Cellular Biology, 2025, 1
DOI: 10.1080/10985549.2025.2532581

The protection of bisphenol A-modulated miRNAs and targets by natural products

Ya-Ting Chuang, Ching-Yu Yen, Wangta Liu, Tsu-Ming Chien, Fang-Rong Chang, Yi-Hong Tsai, Jen-Yang Tang and Hsueh-Wei Chang

Environment International, 2025, 196, 109299
DOI: 10.1016/j.envint.2025.109299

SiJunZi decoction ameliorates bone quality and redox homeostasis and regulates advanced glycation end products/receptor for advanced glycation end products and WNT/β-catenin signaling pathways in diabetic mice

Xuan Dai, Yage Liu, Tianyuan Liu, Yueyi Zhang, Shan Wang, Tianshu Xu, Jiyuan Yin, Hanfen Shi, Zimengwei Ye, Ruyuan Zhu, Junfeng Gao, Guangtong Dong, Dandan Zhao, Sihua Gao, Xinxiang Wang, Marc Prentki, Dieter Brὂmme, Lili Wang and Dongwei Zhang

Journal of Ethnopharmacology, 2024, 319, 117167
DOI: 10.1016/j.jep.2023.117167

Porcine decellularized nerve matrix hydrogel attenuates neuroinflammation after peripheral nerve injury by inhibiting the TLR4/MyD88/NF-κB axis

Rui Li, Jianquan Liu, Liuxun Li, Guotian Luo, Xinrong Yuan, Shichao Shen, Yongpeng Shi, Jianlong Wu, Bin Yan and Lei Yang

Neural Regeneration Research, 2026, 21, 1222
DOI: 10.4103/NRR.NRR-D-24-00302

Synergistic Effect of a Flavonoid-Rich Cocoa–Carob Blend and Metformin in Preserving Pancreatic Beta Cells in Zucker Diabetic Fatty Rats

Paula Gallardo-Villanueva, Tamara Fernández-Marcelo, Laura Villamayor, Angela M. Valverde, Sonia Ramos, Elisa Fernández-Millán and María Angeles Martín

Nutrients, 2024, 16, 273
DOI: 10.3390/nu16020273