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Nanoscale, 2023, 15, 15206
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Structural and componential design: new strategies regulating the behavior of lipid-based nanoparticlesin vivo

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Biomater. Sci., 2023, 11, 4774
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Influence of structural modifications in synthetic vectors of lipid adjuvants on mRNA vaccine delivery

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Biomater. Sci., 2025, 13, 4952
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Fusogenic Coiled-Coil Peptides Enhance Lipid Nanoparticle-Mediated mRNA Delivery upon Intramyocardial Administration

Ye Zeng, Mariona Estapé Senti, M. Clara I. Labonia, Panagiota Papadopoulou, Maike A. D. Brans, Inge Dokter, Marcel H. Fens, Alain van Mil, Joost P. G. Sluijter, Raymond M. Schiffelers, Pieter Vader and Alexander Kros

ACS Nano, 2023, 17, 23466
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Lipid Nanoparticle (LNP) Delivery Carrier-Assisted Targeted Controlled Release mRNA Vaccines in Tumor Immunity

Liusheng Wu, Xiaoqiang Li, Xinye Qian, Shuang Wang, Jixian Liu and Jun Yan

Vaccines, 2024, 12, 186
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Archaeal ether lipids improve internalization and transfection with mRNA lipid nanoparticles

Viktor Laurin Sedlmayr, Silvia Schobesberger, Sarah Spitz, Peter Ertl, David Johannes Wurm, Julian Quehenberger and Oliver Spadiut

European Journal of Pharmaceutics and Biopharmaceutics, 2024, 197, 114213
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Delivering therapeutic RNA into the brain using extracellular vesicles

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Pharmaceutical strategies for optimized mRNA expression

Yingying Shi, Jiapeng Mao, Sijie Wang, Siyao Ma, Lihua Luo and Jian You

Biomaterials, 2025, 314, 122853
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Optimization of a lipid nanoparticle–based protocol for RNA transfection into primary mononuclear phagocytes

Yu Zhang, Louis-Charles Béland, Sabrina Roussel, Nicolas Bertrand, Sébastien S Hébert and Luc Vallières

Journal of Leukocyte Biology, 2024, 115, 1165
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Peptide-Modified Lipid Nanoparticles Boost the Antitumor Efficacy of RNA Therapeutics

Gangyin Zhao, Ye Zeng, Wanli Cheng, Sofia Karkampouna, Panagiota Papadopoulou, Bochuan Hu, Shuya Zang, Emma Wezenberg, Gabriel Forn-Cuní, Bruno Lopes-Bastos, Marianna Kruithof-de Julio, Alexander Kros and B. Ewa Snaar-Jagalska

ACS Nano, 2025, 19, 13685
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In vitro and in vivo evaluation of clinically-approved ionizable cationic lipids shows divergent results between mRNA transfection and vaccine efficacy

Oscar Escalona-Rayo, Ye Zeng, Renzo A. Knol, Thomas J.F. Kock, Dennis Aschmann, Bram Slütter and Alexander Kros

Biomedicine & Pharmacotherapy, 2023, 165, 115065
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Lipid Nanoparticles for mRNA Delivery in Cancer Immunotherapy

Yasir Alshehry, Xiang Liu, Wenhua Li, Qiyan Wang, Janét Cole and Guizhi Zhu

AAPS J, 2025, 27
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Influence of ionisable lipid and sterol variations on lipid nanoparticle properties and performance

Caitlin McMillan, Amy Druschitz, Stephen Rumbelow, Ankita Borah, Rebecca Macfarlane, Zahra Rattray and Yvonne Perrie

Journal of Controlled Release, 2025, 386, 114056
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Effect of mRNA-LNP components of two globally-marketed COVID-19 vaccines on efficacy and stability

Lizhou Zhang, Kunal R. More, Amrita Ojha, Cody B. Jackson, Brian D. Quinlan, Hao Li, Wenhui He, Michael Farzan, Norbert Pardi and Hyeryun Choe

npj Vaccines, 2023, 8
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Analytical Ultracentrifugation to Assess the Quality of LNP-mRNA Therapeutics

Giuditta Guerrini, Dora Mehn, Diletta Scaccabarozzi, Sabrina Gioria and Luigi Calzolai

IJMS, 2024, 25, 5718
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Nanotechnology boosts the efficiency of tumor diagnosis and therapy

Ying Yang, Mali Lin, Mengfan Sun, Guo-Qiang Zhang, Jianshuang Guo and Jianheng Li

Front. Bioeng. Biotechnol., 2023, 11
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Lipid Nanoparticle (LNP) ‐A Vector Suitable for Evolving Therapies for Advanced Hepatocellular Carcinoma (HCC)

Mingxuan Zhang, Ruiping Guo, Zhuhui Yuan and Hao Wang

Global Challenges, 2025, 9
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A universal viral capsid protein based one step RNA synthesis and packaging system for rapid and efficient mRNA vaccine development

Jiayue Su, Jinsong Zhang, Xiangning Feng, Jinsong Liu, Shan Gao, Xinrui Liu, Mingwei Yang and Zeliang Chen

Molecular Therapy, 2025, 33, 1720
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Immune response to the components of lipid nanoparticles for ribonucleic acid therapeutics

Sunny P Chen and Anna K Blakney

Current Opinion in Biotechnology, 2024, 85, 103049
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Lipid- and Polymer-Based Nanocarrier Platforms for Cancer Vaccine Delivery

Suhair Sunoqrot, Sara A. Abdel Gaber, Razan Abujaber, May Al-Majawleh and Shahd Talhouni

ACS Appl. Bio Mater., 2024, 7, 4998
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Theranostic Lipid Nanoparticles for Renal Cell Carcinoma

Xiongmin Mao, Guanyi Wang, Zijian Wang, Chen Duan, Xiaoliang Wu and Hua Xu

Advanced Materials, 2025, 37
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mRNA vaccines and their delivery strategies: A journey from infectious diseases to cancer

RamaRao Malla, Mundla Srilatha, Batoul Farran and Ganji Purnachandra Nagaraju

Molecular Therapy, 2024, 32, 13
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Navigating the intricate in-vivo journey of lipid nanoparticles tailored for the targeted delivery of RNA therapeutics: a quality-by-design approach

Elahe Haghighi, Samira Sadat Abolmaali, Ali Dehshahri, Seyed Ali Mousavi Shaegh, Negar Azarpira and Ali Mohammad Tamaddon

J Nanobiotechnol, 2024, 22
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Transition Temperature-Guided Design of Lipid Nanoparticles for Effective mRNA Delivery

Jeong Eun Shin, Eun-jeong Won, Junchao Xu, Jong Cheol Lee, Jeong Kyu Bang, Michael J. Mitchell and Hyunjoo Cha-Molstad

ACS Appl. Mater. Interfaces, 2025, 17, 28012
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Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery

Qimanguli Saiding, Zhongyang Zhang, Shuying Chen, Fan Xiao, Yumeng Chen, Yongjiang Li, Xueyan Zhen, Muhammad Muzamil Khan, Wei Chen, Seyoung Koo, Na Kong and Wei Tao

Advanced Drug Delivery Reviews, 2023, 203, 115116
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A highly stable lyophilized mRNA vaccine for Herpes Zoster provides potent cellular and humoral responses

Raquel Munoz-Moreno, Viola Allaj, Eddie Gadee, Julie M. Button, Fernando Diaz, Mohan S. Maddur, Wei Chen, Cheng Hui Hu, Lyndsey Martinez, Andreas Giannakou, Adam Lee Campbell, Yana Miteva, Pengbo Guo, Bridget Huang, Shuai Shi, Jason Lotvin, Kristin Tompkins, Pirada Suphaphiphat Allen and Alicia Solórzano

npj Vaccines, 2025, 10
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Leveraging high-throughput screening technologies in targeted mRNA delivery

Yuchen Zhang, Zhifei Gao, Xiao Yang, Qinglong Xu and Yao Lu

Materials Today Bio, 2024, 26, 101101
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Intratumoral delivery of lipid nanoparticle-formulated mRNA encoding IL-21, IL-7, and 4-1BBL induces systemic anti-tumor immunity

Ahmed E. I. Hamouda, Jessica Filtjens, Elisabeth Brabants, Daliya Kancheva, Ayla Debraekeleer, Jan Brughmans, Lotte Jacobs, Pauline M. R. Bardet, Elisabeth Knetemann, Pierre Lefesvre, Lize Allonsius, Mark Gontsarik, Ismael Varela, Marian Crabbé, Emile J. Clappaert, Federica Cappellesso, Aarushi A. Caro, Alícia Gordún Peiró, Luna Fredericq, Eva Hadadi, Mariona Estapé Senti, Raymond Schiffelers, Leo A. van Grunsven, Frank Aboubakar Nana, Bruno G. De Geest, Sofie Deschoemaeker, Stefaan De Koker, Florence Lambolez and Damya Laoui

Nat Commun, 2024, 15
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RNA-encapsulating lipid nanoparticles in cancer immunotherapy: From pre-clinical studies to clinical trials

Tiffaney Hsia and Yunching Chen

European Journal of Pharmaceutics and Biopharmaceutics, 2024, 197, 114234
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T Cell-Targeting Nanotherapies for Atherosclerosis

Karla Lambaren, Noah Trac, Daniel Fehrenbach, Meena Madhur and Eun Ji Chung

Bioconjugate Chem., 2025, 36, 332
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mRNA-LNPs induce immune activation and cytokine release in human whole blood assays across diverse health conditions

Hong-My Nguyen, Kristin E. Alexander, Mark Collinge, James C. Hickey, Thomas A. Lanz, Jin Li, Mark J. Sheehan, Leah C. Newman and Mitchell Thorn

Molecular Therapy, 2025, 33, 2872
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