Advanced polymeric systems for colon drug delivery: from experimental models to market applications

R. Crispino, E. Lagreca, A. Procopio, R. D’Auria, B. Corrado, S. La Manna, V. Onesto and C. Di Natale

Soft Matter, 2025, 21, 792
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Combinatorial microneedle patch with tunable release kinetics and dual fast-deep/sustained release capabilities

Miguel Angel Lopez-Ramirez, Daniel Kupor, Leonardo Marchiori, Fernando Soto, Ricardo Rueda, Maria Reynoso, Lakshmi Rekha Narra, Krishnan Chakravarthy and Joseph Wang

J. Mater. Chem. B, 2021, 9, 2189
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Recent progress in PLGA-based microneedle-mediated transdermal drug and vaccine delivery

Atefeh Malek-Khatabi, Malihe Sadat Razavi, Alyeh Abdollahi, Milad Rahimzadeghan, Fatemeh Moammeri, Mojgan Sheikhi, Mohamadreza Tavakoli, Mazda Rad-Malekshahi and Zahra Faraji Rad

Biomater. Sci., 2023, 11, 5390
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Polymeric microneedles for transdermal drug delivery- a review of recent studies

Ziaul Karim, Preeti Karwa and Shobha Rani R. Hiremath

Journal of Drug Delivery Science and Technology, 2022, 77, 103760
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Self-Assembling Peptides: From Design to Biomedical Applications

Sara La Manna, Concetta Di Natale, Valentina Onesto and Daniela Marasco

IJMS, 2021, 22, 12662
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Implantable Microarray Patch: Engineering at the Nano and Macro Scale for Sustained Therapeutic Release via Synthetic Biodegradable Polymers

Li Zhao, Akmal Hidayat Bin Sabri, Mary B. McGuckin, Linlin Li, Zihao Wang, Eneko Larrañeta and Ryan F. Donnelly

Adv Materials Technologies, 2025, 10
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Dissolving and Swelling Hydrogel-Based Microneedles: An Overview of Their Materials, Fabrication, Characterization Methods, and Challenges

Bana Shriky, Maksims Babenko and Ben R. Whiteside

Gels, 2023, 9, 806
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Nano-PhotoCrystals (Photosensitive Nanocrystals) of Aloe Emodin Combined with Dissolving Microneedles for Dual Smart Targeting of Acute Bacterial Skin and Soft Tissue Infections

Abraham M. Abraham, Qonita Kurnia Anjani, Eduard Preis, Yara A. Naser, Lena Bender, Franziska Bär, Udo Bakowsky, Elise Catlin, Alejandro J. Paredes, Lalitkumar K. Vora, Eneko Larrañeta and Ryan F. Donnelly

ACS Appl. Mater. Interfaces, 2025, 17, 65460
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Long-acting microneedle formulations

Lalitkumar K. Vora, Akmal H. Sabri, Yara Naser, Achmad Himawan, Aaron R.J. Hutton, Qonita Kurnia Anjani, Fabiana Volpe-Zanutto, Deepakkumar Mishra, Mingshan Li, Aoife M. Rodgers, Alejandro J. Paredes, Eneko Larrañeta, Raghu Raj Singh Thakur and Ryan F. Donnelly

Advanced Drug Delivery Reviews, 2023, 201, 115055
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Colorimetric sensing for transdermal phospho-Tau 181 detection mediated by wearable microneedle functionalized with gold nanoparticle (MN-AuNP)

Anna Palma, Concetta Di Natale, Daniele Tammaro, Elena Lagreca, Gennaro Giordano, Simone Russo, Giuseppe Vitiello, Vincenzo Ferraro, Veronica Vespini, Simonetta Grilli, Pier Luca Maffettone and Sara Coppola

Talanta, 2026, 300, 129198
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Biomaterials for Regenerative Medicine in Italy: Brief State of the Art of the Principal Research Centers

Francesca Camponogara, Federica Zanotti, Martina Trentini, Elena Tiengo, Ilaria Zanolla, Elham Pishavar, Elisa Soliani, Marco Scatto, Paolo Gargiulo, Ylenia Zambito, Luca De Stefano, Letizia Ferroni and Barbara Zavan

IJMS, 2022, 23, 8245
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Sensitive colorimetric immunosensor using AuNP-functionalized polymer film for picogram-level detection of Tau protein intermediate aggregates

Concetta Di Natale, Simone Russo, Fabiana Graziano, Veronica Vespini, Giuseppina Luciani, Giuseppe Vitiello, Lorenzo Lombardi, Francesca Ferranti, Silvia Mari, Pier Luca Maffettone, Simonetta Grilli, Sara Coppola and Pietro Ferraro

Journal of Colloid and Interface Science, 2025, 678, 1052
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PLGA microparticle formulations for tunable delivery of a nano-engineered filamentous bacteriophage-based vaccine: in vitro and in silico-supported approach

Rezvan Jamaledin, Rossella Sartorius, Concetta Di Natale, Valentina Onesto, Roberta Manco, Valentina Mollo, Raffaele Vecchione, Piergiuseppe De Berardinis and Paolo Antonio Netti

J Nanostruct Chem, 2024, 14, 307
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Electroanalytical Sensor Based on Gold-Nanoparticle-Decorated Paper for Sensitive Detection of Copper Ions in Sweat and Serum

Neda Bagheri, Vincenzo Mazzaracchio, Stefano Cinti, Noemi Colozza, Concetta Di Natale, Paolo Antonio Netti, Mohammad Saraji, Simona Roggero, Danila Moscone and Fabiana Arduini

Anal. Chem., 2021, 93, 5225
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A review of existing strategies for designing long-acting parenteral formulations: Focus on underlying mechanisms, and future perspectives

Yujie Shi, An Lu, Xiangyu Wang, Zakia Belhadj, Jiancheng Wang and Qiang Zhang

Acta Pharmaceutica Sinica B, 2021, 11, 2396
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Mapping the Mechanical and Immunological Profiles of Polymeric Microneedles to Enable Vaccine and Immunotherapy Applications

Shrey A. Shah, Robert S. Oakes, Senta M. Kapnick and Christopher M. Jewell

Front. Immunol., 2022, 13
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Recent Fabrication Methods to Produce Polymer-Based Drug Delivery Matrices (Experimental and In Silico Approaches)

Anna Procopio, Elena Lagreca, Rezvan Jamaledin, Sara La Manna, Brunella Corrado, Concetta Di Natale and Valentina Onesto

Pharmaceutics, 2022, 14, 872
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Dual responsive block copolymer coated hollow mesoporous silica nanoparticles for glucose-mediated transcutaneous drug delivery

Yaping Wang, Songyue Cheng, Wendi Fan, Yikun Jiang, Jie Yang, Zaizai Tong and Guohua Jiang

Chinese Journal of Chemical Engineering, 2022, 51, 35
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Highly sensitive detection of different aggregation stages of Aβ1-42 -amyloid peptide in urine-like samples by auto-fluorescence

Concetta Di Natale, Sara La Manna, Stefania Carbone, Sara Coppola, Veronica Vespini, Volodymyr Tkachenko, Daniele Tammaro, Simone Russo, Giuseppe Vitiello, Giuseppina Luciani, Daniela Marasco, Pier Luca Maffettone, Pietro Ferraro and Simonetta Grilli

Analytica Chimica Acta, 2025, 1374, 344531
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Polymer-Based Designer Particles as Drug Carriers: Strategies to Construct and Modify

Nidhi Gupta and Sampa Saha

ACS Appl. Bio Mater., 2025, 8, 4432
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Improved Therapeutic Efficiency against Obesity through Transdermal Drug Delivery Using Microneedle Arrays

Yixuan Xie, Ruomei Shao, Yali Lin, Chunnan Wang, Ying Tan, Weidong Xie and Shuqing Sun

Pharmaceutics, 2021, 13, 827
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The most promising microneedle device: present and future of hyaluronic acid microneedle patch

Huizhi Kang, Zhuo Zuo, Ru Lin, Muzi Yao, Yang Han and Jing Han

Drug Delivery, 2022, 29, 3087
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Engineered microneedles arrays for wound healing

Shun Yao, Yuan Luo and Yongan Wang

Engineered Regeneration, 2022, 3, 232
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Levels of 24-hydroxycholesteryl esters in cerebrospinal fluid and plasma from patients with amyotrophic lateral sclerosis

Concetta Di Natale, Alessandra Monaco, Carlo Pedone, Francesca Trojsi, Gioacchino Tedeschi, Paolo Antonio Netti and Paolo Abrescia

Journal of Pharmaceutical and Biomedical Analysis, 2023, 226, 115244
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Open Porous Composite Monoliths for Biomedical Applications via Photocrosslinking of Low Internal Phase Nano-Emulsion Templates

Maurizio Celentano, Raffaele Vecchione, Maddalena De Simone, Eliana Esposito, Monica Patrone and Paolo Antonio Netti

Applied Sciences, 2021, 11, 5338
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Polylactic‐ Glycolic Acid Microparticles–Encapsulated Prostaglandin E1 as A Novel Strategy In Triple Negative Breast Cancer

Concetta Di Natale, Elena Lagreca, Raffaele Crispino, Roberta D’Auria, Alessandro Attanasio, Rezvan Jamaledin, Raffaele Vecchione and Paolo Antonio Netti

ChemistryOpen, 2025, 14
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PEGylated SOCS3 Mimetics Encapsulated into PLGA-NPs as Selective Inhibitors of JAK/STAT Pathway in TNBC Cells

Sara La Manna, Alessia Cugudda, Flavia Mercurio, Marilisa Leone, Sara Fortuna, Concetta Di Natale, Elena Lagreca, Paolo Antonio Netti, Valeria Panzetta and Daniela Marasco

IJN, 2024, Volume 19, 7237
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Smart and sustainable 3D-printed electrochemical device for diclofenac remediation and monitoring in water

Gabriella Iula, Ada Raucci, Lorenzo Antonelli, Panagiota M. Kalligosfyri, Massimo Giuseppe De Cesaris, Nina Felli, Concetta Di Natale, Stefano Cinti and Alessandra Gentili

Talanta, 2026, 297, 128597
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Characterization of bovine serum albumin immobilization on surface modified glass slides in case of pyro-electrohydrodynamic spots

Concetta Di Natale, Sara Coppola, Veronica Vespini, Volodymyr Tkachenko, Giuseppina Luciani, Giuseppe Vitiello, Francesca Ferranti, Silvia Mari, Pier Luca Maffettone and Simonetta Grilli

Analytica Chimica Acta, 2024, 1329, 343178
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Morphological and Rheological Guided Design for the Microencapsulation Process of Lactobacillus paracasei CBA L74 in Calcium Alginate Microspheres

Concetta Di Natale, Elena Lagreca, Valeria Panzetta, Marianna Gallo, Francesca Passannanti, Michele Vitale, Sabato Fusco, Raffaele Vecchione, Roberto Nigro and Paolo Netti

Front. Bioeng. Biotechnol., 2021, 9
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Biomimetic Oil-in-Water Nanoemulsions as a Suitable Drug Delivery System to Target Inflamed Endothelial Cells

Elena Lagreca, Elisabetta Caiazzo, Concetta Di Natale, Valentina Mollo, Raffaele Vecchione, Armando Ialenti and Paolo Antonio Netti

Nanomaterials, 2024, 14, 1286
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Conformational consequences of NPM1 rare mutations: An aggregation perspective in Acute Myeloid Leukemia

Sara La Manna, Daniele Florio, Concetta Di Natale, Fabiana Napolitano, Anna Maria Malfitano, Paolo A. Netti, Ilaria De Benedictis and Daniela Marasco

Bioorganic Chemistry, 2021, 113, 104997
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Cell Membrane-Coated Oil in Water Nano-Emulsions as Biomimetic Nanocarriers for Lipophilic Compounds Conveyance

Martina Profeta, Concetta Di Natale, Elena Lagreca, Valentina Mollo, Paolo Antonio Netti and Raffaele Vecchione

Pharmaceutics, 2021, 13, 1069
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Review on engineered polymer microneedles for drug delivery and disease diagnosis

Yan Li, Zhenyu Wu, Yan Zhou, Sedrati Manar, Rui Wang and Guohua Jiang

Biofabrication, 2025, 17, 042001
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NIRDye 812: A molecular platform tailored for multimodal bioimaging applications of targeted fluorescence- and photoacoustic-guided surgery

Kenneth S. Hettie and Frederick T. Chin

Journal of Photochemistry and Photobiology B: Biology, 2023, 242, 112683
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Engineered Bacterial Cellulose Nanostructured Matrix for Incubation and Release of Drug-Loaded Oil in Water Nanoemulsion

Concetta Di Natale, Vincenza De Gregorio, Elena Lagreca, Francesca Mauro, Brunella Corrado, Raffaele Vecchione and Paolo Antonio Netti

Front. Bioeng. Biotechnol., 2022, 10
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Highly sensitive detection of the neurodegenerative biomarker Tau by using the concentration effect of the pyro-electrohydrodynamic jetting

Concetta Di Natale, Sara Coppola, Veronica Vespini, Volodymyr Tkachenko, Simone Russo, Giuseppina Luciani, Giuseppe Vitiello, Francesca Ferranti, Silvia Mari, Pietro Ferraro, Pier Luca Maffettone and Simonetta Grilli

Biosensors and Bioelectronics, 2024, 254, 116234
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