Recent advances in DNA-encoded dynamic libraries

Bingbing Shi, Yu Zhou and Xiaoyu Li

RSC Chem. Biol., 2022, 3, 407
DOI: 10.1039/D2CB00007E

Recent Advances on the Selection Methods of DNA‐Encoded Libraries

Yiran Huang and Xiaoyu Li

ChemBioChem, 2021, 22, 2384
DOI: 10.1002/cbic.202100144

Modulation of the lipophilicity and molecular size of thiosemicarbazone inhibitors to regulate tyrosinase activity

Shuhong Cao, Dandan Wang, Run Cheng, Wenyan Shi, Qinfang Zhang, Huajin Zeng and Jingwen Chen

Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 281, 121590
DOI: 10.1016/j.saa.2022.121590

Heterocyclic Compounds as Synthetic Tyrosinase Inhibitors: Recent Advances

Serena Vittorio, Christian Dank and Laura Ielo

IJMS, 2023, 24, 9097
DOI: 10.3390/ijms24109097

Protein-templated ligand discovery via the selection of DNA-encoded dynamic libraries

Yu Zhou, Wenyin Shen, Ying Gao, Jianzhao Peng, Qingrong Li, Xueying Wei, Shihao Liu, Fong Sang Lam, Joan Mayol-Llinàs, Guixian Zhao, Gang Li, Yizhou Li, Hongzhe Sun, Yan Cao and Xiaoyu Li

Nat. Chem., 2024, 16, 543
DOI: 10.1038/s41557-024-01442-y

Control of the antitumour activity and specificity of CAR T cells via organic adapters covalently tethering the CAR to tumour cells

Alexey V. Stepanov, Jia Xie, Qiaoqiao Zhu, Zuyuan Shen, Wenji Su, Letian Kuai, Richard Soll, Christoph Rader, Geramie Shaver, Lacey Douthit, Ding Zhang, Roman Kalinin, Xiang Fu, Yingying Zhao, Tian Qin, Phil S. Baran, Alexander G. Gabibov, David Bushnell, Dario Neri, Roger D. Kornberg and Richard A. Lerner

Nat. Biomed. Eng, 2023, 8, 529
DOI: 10.1038/s41551-023-01102-5

Selective tumor targeting enabled by picomolar fibroblast activation protein inhibitors isolated from a DNA-encoded affinity maturation library

Sara Puglioli, Eleonore Schmidt, Christian Pellegrino, Luca Prati, Sebastian Oehler, Roberto De Luca, Andrea Galbiati, Claudia Comacchio, Lisa Nadal, Jörg Scheuermann, Markus G. Manz, Dario Neri, Samuele Cazzamalli, Gabriele Bassi and Nicholas Favalli

Chem, 2023, 9, 411
DOI: 10.1016/j.chempr.2022.10.006

Identification of isoform/domain-selective fragments from the selection of DNA-encoded dynamic library

Yu Zhou, Wenyin Shen, Jianzhao Peng, Yuqing Deng and Xiaoyu Li

Bioorganic & Medicinal Chemistry, 2021, 45, 116328
DOI: 10.1016/j.bmc.2021.116328

Computational methods to analyze and predict the binding mode of inhibitors targeting both human and mushroom tyrosinase

Federico Ricci, Kristina Schira, Lyna Khettabi, Lisa Lombardo, Salvatore Mirabile, Rosaria Gitto, Montserrat Soler-Lopez, Jörg Scheuermann, Gerhard Wolber and Laura De Luca

European Journal of Medicinal Chemistry, 2023, 260, 115771
DOI: 10.1016/j.ejmech.2023.115771

Advancing small-molecule drug discovery by encoded dual-display technologies

Alice Lessing, Dimitar Petrov and Jörg Scheuermann

Trends in Pharmacological Sciences, 2023, 44, 817
DOI: 10.1016/j.tips.2023.08.006