Toxicity of zearalenone and its nutritional intervention by natural products

Siyuan Jing, Chunmei Liu, Jian Zheng, Zhijian Dong and Na Guo

Food Funct., 2022, 13, 10374
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Protective effects of lycopene against zearalenone-induced reproductive toxicity in early pregnancy through anti-inflammatory, antioxidant and anti-apoptotic effects

Jungang Kang, Yang Li, Zhanfei Ma, Yabo Wang, Weifeng Zhu and Guojun Jiang

Food and Chemical Toxicology, 2023, 179, 113936
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Targeting programmed cell death with natural products: a potential therapeutic strategy for diminished ovarian reserve and fertility preservation

Wenhan Ju, Shuai Zhao, Danping Li, Jinfu Zhang, Shan Xiang and Fang Lian

Front. Pharmacol., 2025, 16
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Reproductive toxicity and action mechanism of the estrogen zearalenone: A review

Xiaoguang Chen, Wenjuan Wei, Wenjing Xu, Qiongxia Lv, Ziqiang Zhang and Yumei Liu

Chemico-Biological Interactions, 2025, 420, 111701
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In vitro exposure of sheep ovarian tissue to the xenoestrogens zearalenone and enterolactone: Effects on preantral follicles

I.P. Silva, D.C.C. Brito, T.E.S. Silva, R.F. Silva, M.I.F. Guedes, J.Y.G. Silva, A.P.R. Rodrigues, R.R. Santos and J.R. Figueiredo

Theriogenology, 2021, 174, 124
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Recent trends in fluorescent aptasensors for mycotoxin detection in food: Principles, constituted elements, types, and applications

Xiaohai Yan, Hong Chen, Gengan Du, Qi Guo, Yahong Yuan and Tianli Yue

Food Frontiers, 2022, 3, 428
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Study on the mechanism of scutellarin's protective effect against ZEA-induced mouse ovarian granulosa cells injury

Yanyan Yi, Zhili Hao, Panpan Sun, Kuohai Fan, Wei Yin, Jianhua Guo, Xiaozhong Zheng, Na Sun and Hongquan Li

Food and Chemical Toxicology, 2022, 170, 113481
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Mycotoxin toxicity and its alleviation strategy on female mammalian reproduction and fertility

Ping-Shuang Lu and Shao-Chen Sun

Journal of Advanced Research, 2025
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chi‐miR‐130b‐3p regulates the ZEA‐induced oxidative stress damage through the KEAP1/NRF2 signaling pathway by targeting SESN2 in goat GCs

Liang Liu, Jianyu Ma, Zongyou Wei, Yingnan Yang, Zifei Liu, Dongxu Li, Xiaoqing Yu, Yixuan Fan, Feng Wang and Yongjie Wan

The FASEB Journal, 2023, 37
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Vitamin E Mitigates Apoptosis in Ovarian Granulosa Cells by Inhibiting Zearalenone-Induced Activation of the PERK/eIF-2α/ATF4/Chop Signaling Pathway

Qingxiu Liu, Leli Wang, Lei An, Yafei Liu, Honglei Qu, Shimeng Huang, Lihong Zhao, Yulong Yin and Qiugang Ma

J. Agric. Food Chem., 2024, 72, 28390
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Zearalenone causes ovarian damage and abnormal estradiol secretion in meat rabbits by inducing oxidative stress and inflammatory responses

Fengyang Wu, Fengxia Wang, Zhaohong Tang, Xinyu Yang, Yanhua Liu, Man Zhao, Shudong Liu, Shuaijuan Han and Baojiang Chen

Front. Vet. Sci., 2025, 12
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SO2 derivatives impair ovarian function by inhibiting Serpine1/NF-κB pathway-mediated ovarian granulosa cell survival

Shanshan Wu, Xudong Zhang, Yimeng Lu, Yujiu Ma, Xiaohan Qi, Xinxin Wang and Jichun Tan

Journal of Hazardous Materials, 2025, 487, 137116
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Scutellarein stimulates human sperm function by increasing the levels of intracellular calcium and tyrosine phosphorylation

Zhihong Sun, Wenqing Xu, Yuan Yuan, Dandan Song, Houyang Chen, Tao Luo and Ying Chen

Andrologia, 2022, 54
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Research Progress of Safety of Zearalenone: A Review

Xiao Han, Bingxin Huangfu, Tongxiao Xu, Wentao Xu, Charles Asakiya, Kunlun Huang and Xiaoyun He

Toxins, 2022, 14, 386
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Selenium-Chitosan Protects Porcine Endometrial Epithelial Cells from Zearalenone-induced Apoptosis via the JNK/SAPK Signaling Pathway

Huanhuan Wang, Fuze She, Fu Chen, Kun Li and Shunyi Qin

Biol Trace Elem Res, 2024, 202, 2075
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Network pharmacology-based study on the mechanism of scutellarin against zearalenone-induced ovarian granulosa cell injury

Panpan Hu, Na Sun, Ajab khan, Xinyue Zhang, Panpan Sun, Yaogui Sun, Jianhua Guo, Xiaozhong Zheng, Wei Yin, Kuohai Fan, Jianzhong Wang, Huizhen Yang and Hongquan Li

Ecotoxicology and Environmental Safety, 2021, 227, 112865
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Forsythoside A protects against Zearalenone-induced cell damage in chicken embryonic fibroblasts via mitigation of endoplasmic reticulum stress

Hui Hu, Qiang Yu, Yu Zheng, Hongjie Cui, Xiaohong Huang and Kaizhao Zhang

Vet Res Commun, 2024, 48, 1659
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Scutellarin targets Wnt5a against zearalenone-induced apoptosis in mouse granulosa cells in vitro and in vivo

Na Sun, Abdul Haseeb, Panpan Sun, Hua Zhang, Jia Zhong, Wei Yin, Kuohai Fan, Huizhen Yang, Zhenbiao Zhang, Yaogui Sun, Panpan Hu and Hongquan Li

Journal of Hazardous Materials, 2024, 464, 132917
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Heme Oxygenase-1 Regulates Zearalenone-Induced Oxidative Stress and Apoptosis in Sheep Follicular Granulosa Cells

Yina Li, Yujin Gao, Dan Yao, Zongshuai Li, Jiamian Wang, Xijun Zhang, Xingxu Zhao and Yong Zhang

IJMS, 2024, 25, 2578
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The effects of natural products and bioactive ingredients of traditional Chinese medicine on apoptosis of ovarian granulosa cells

Lulu Zhong, Yue Luo, Feng Zhou, Xuebin Yang, Yang Tan, Shunmin Li and Gang Pei

J of Applied Toxicology, 2023, 43, 772
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Zearalenone Induces Dopaminergic Neurodegeneration via DRP-1-Involved Mitochondrial Fragmentation and Apoptosis in a Caenorhabditis elegans Parkinson’s Disease Model

Chia-Cheng Wei, Nien-Chieh Yang and Chi-Wei Huang

J. Agric. Food Chem., 2021, 69, 12030
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Effects of Zearalenone on Apoptosis and Copper Accumulation of Goat Granulosa Cells In Vitro

Liang Liu, Jianyu Ma, Zongyou Wei, Yingnan Yang, Dongxu Li and Yongjie Wan

Biology, 2023, 12, 100
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