Advances in chlorin-based photodynamic therapy with nanoparticle delivery system for cancer treatment

Lin Huang, Sajid Asghar, Ting Zhu, Panting Ye, Ziyi Hu, Zhipeng Chen and Yanyu Xiao

Expert Opinion on Drug Delivery, 2021, 18, 1473
DOI: 10.1080/17425247.2021.1950685

Application of Biomimetic Cell Membrane-Coated Nanocarriers in Cardiovascular Diseases

Xufei Zhao, Wu Chen, Jiong Wu, Yan Shen, Bohui Xu, Zhen Chen and Yangyong Sun

IJN, 2025, Volume 20, 8249
DOI: 10.2147/IJN.S531558

Biomimetic Boron Nitride Nanoparticles for Targeted Drug Delivery and Enhanced Antitumor Activity

Hui Li, Wei Qiao, Yizhe Shen, Huashan Xu, Yuan Fan, Yuxiang Liu, Yadi Lan, Yan Gong, Fuxue Chen and Shini Feng

Pharmaceutics, 2023, 15, 1269
DOI: 10.3390/pharmaceutics15041269

Natural, Engineered, and Hybrid Platelet Membrane–Based Nanotherapeutics for Inflammatory Diseases

Boyuan Liu, Yongjie Wang, Weiquan Gong, Song Han, Zhenshan Lv, Zilin Zhang, Jinwei Qi, Aijun Song, Zongyuan Yang, Longfei Duan, Tianhui Zhang and Zhenyu Wang

IJN, 2025, Volume 20, 14149
DOI: 10.2147/IJN.S558928

Pharmacological properties and underlying mechanisms of aurantio‑obtusin (Review)

Yao Liu, Xuemei Sun, Xinpei Hu, Yitian Xu, Teng Li and Zhigui Wu

Exp Ther Med, 2023, 26
DOI: 10.3892/etm.2023.12079

From bench to bedside: Platelet biomimetic nanoparticles as a promising carriers for personalized drug delivery

Ammara Safdar, Peina Wang, Abdul Muhaymin, Guangjun Nie and Suping Li

Journal of Controlled Release, 2024, 373, 128
DOI: 10.1016/j.jconrel.2024.07.013

Multifunctional magnetic MOF under cover of erythrocytes for ROS scavenging and magnetic hyperthermia thrombolysis

Pengpeng Guan, Caijie Yuan, Jiali Li, Zhou Wen, Enling Hu, Guangqian Lan, Bowen Cheng, Yinggui Huang and Fei Lu

Chemical Engineering Journal, 2025, 515, 163939
DOI: 10.1016/j.cej.2025.163939

Reactive oxygen species-responsive nanocarrier ameliorates murine colitis by intervening colonic innate and adaptive immune responses

Xiangji Yan, Lingzhang Meng, Xingzhe Zhang, Zhichao Deng, Bowen Gao, Yujie Zhang, Mei Yang, Yana Ma, Yuanyuan Zhang, Kangsheng Tu, Mingzhen Zhang and Qiuran Xu

Molecular Therapy, 2023, 31, 1383
DOI: 10.1016/j.ymthe.2023.02.017

Nanomaterials: A Promising Therapeutic Approach for Cardiovascular Diseases

Hitesh Chopra, Shabana Bibi, Awdhesh Kumar Mishra, Vineet Tirth, Sree Vandana Yerramsetty, Sree Varshini Murali, Syed Umair Ahmad, Yugal Kishore Mohanta, Mohamed S. Attia, Ali Algahtani, Fahadul Islam, Abdul Hayee, Saiful Islam, Atif Amin Baig, Talha Bin Emran and N Senthilkumar

Journal of Nanomaterials, 2022, 2022
DOI: 10.1155/2022/4155729

Platelet-Membrane-Encapsulated Carvedilol with Improved Targeting Ability for Relieving Myocardial Ischemia–Reperfusion Injury

Tingting Zhou, Xuechao Yang, Tianyi Wang, Mingming Xu, Zhanghao Huang, Runze Yu, Yi Jiang, Youlang Zhou and Jiahai Shi

Membranes, 2022, 12, 605
DOI: 10.3390/membranes12060605

Advancements in nanomedicine for modulating ischemic cardiomyopathy therapy

Xiangyi Ren, Yan Wang, Jian Yang, Mengli Zhu, Ling Zhang and Lin Li

Materials Today Bio, 2025, 34, 102238
DOI: 10.1016/j.mtbio.2025.102238

Advances of nanomedicine in treatment of atherosclerosis and thrombosis

Yu Mao, Jun Ren and Lifang Yang

Environmental Research, 2023, 238, 116637
DOI: 10.1016/j.envres.2023.116637

Magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery

Yu Chen, Haifu Sun, Yonggang Li, Xixi Han, Yuqing Yang, Zheng Chen, Xuequan Zhao, Yuchen Qian, Xishui Liu, Feng Zhou, Jiaxiang Bai and Yusen Qiao

Bioactive Materials, 2025, 53, 591
DOI: 10.1016/j.bioactmat.2025.07.033

Engineering Hyperechogenic Colloids with Clot-Targeting Capabilities from Platelet-Derived Membranes

Mark Louis P. Vidallon, Mitchell J. Moon, Haikun Liu, Yuyang Song, Simon Crawford, Boon Mian Teo, James D. McFadyen, Alexis I. Bishop, Rico F. Tabor, Karlheinz Peter and Xiaowei Wang

ACS Appl. Mater. Interfaces, 2024
DOI: 10.1021/acsami.4c12024

Biomimetic platelet membrane-coated nanoparticles for targeted therapy

Huijie Han, Raquel Bártolo, Jiachen Li, Mohammad-Ali Shahbazi and Hélder A. Santos

European Journal of Pharmaceutics and Biopharmaceutics, 2022, 172, 1
DOI: 10.1016/j.ejpb.2022.01.004

Fibrinogen binding to activated platelets and its biomimetic thrombus-targeted thrombolytic strategies

Yu Huang, Jiahua Wang, Yuanyuan Guo, Lingyue Shen and Yuehua Li

International Journal of Biological Macromolecules, 2024, 274, 133286
DOI: 10.1016/j.ijbiomac.2024.133286

Cellular and molecular mechanisms of thrombosis and thrombus-targeted thrombolytic strategies

Xuehao Yu, Jinlong Zhang, Yidan Zhang, Jiahua Wang, Yao Zhao, Mei Wang, Yuanyuan Guo, Yuehua Li and Yu Huang

Materials Today Bio, 2025, 35, 102534
DOI: 10.1016/j.mtbio.2025.102534

Biodegradable Iodinated Polymeric Nanoparticle as a Computed Tomography Contrast Agent for Direct Imaging of Cerebral Thrombus

Hyun Jae Park, Subin Park, In Jae Chung, Hee Jeong Jang, Leesu Lee, Tae Hoon Kim, Dong-Eog Kim and Cheol-Hee Ahn

ACS Nano, 2026
DOI: 10.1021/acsnano.6c01281

Application of Nanotechnology in Thrombus Therapy

Shuyin Zhou, Wenbo Zhao, Jinglei Hu, Chun Mao and Min Zhou

Adv Healthcare Materials, 2023, 12
DOI: 10.1002/adhm.202202578

ATP-Responsive Multifunctional Supramolecular Polymer as a Nonviral Vector for Boosting Cholesterol Removal from Lipid-Laden Macrophages

Cuiping Jiang, Yuan Wang, Peiyi Liang, Yao Chen, Ziming Zhuang, Lu Zhang, Yankui Yi, Li Liu and Qiang Liu

ACS Biomater. Sci. Eng., 2021, 7, 5048
DOI: 10.1021/acsbiomaterials.1c00919

Platelet Membrane-Coated r-SAK Improves Thrombolytic Efficacy by Targeting Thrombus

Rui Hua, Mingxi Li, Qingxia Lin, Mengying Dong, Xiaoxuan Gong, Zhenyu Lin, Yule Li, Chen Li, Tian Wu, Chunyue Tan, Wenhao Zhang, Qin Wang, Tianyu Wu, Xiaoyu Zhou, Fang Yang and Chunjian Li

ACS Appl. Mater. Interfaces, 2024, 16, 21438
DOI: 10.1021/acsami.3c18402

Recent Advances of Cell Membrane Coated Nanoparticles in Treating Cardiovascular Disorders

Chaojie Zhu, Junkai Ma, Zhiheng Ji, Jie Shen and Qiwen Wang

Molecules, 2021, 26, 3428
DOI: 10.3390/molecules26113428

Nanomaterial interventions in abdominal aortic aneurysm (AAA): From microenvironment modulation to vascular reconstruction

Han Jiang, Ting Li, Yumeng Yan and Yu Lun

Colloids and Surfaces B: Biointerfaces, 2026, 262, 115548
DOI: 10.1016/j.colsurfb.2026.115548

Platelet Membrane-Encapsulated Poly(lactic-co-glycolic acid) Nanoparticles Loaded with Sildenafil for Targeted Therapy of Vein Graft Intimal Hyperplasia

Fajing Yang, Yihui Qiu, Xueting Xie, Xingjian Zhou, Shunfu Wang, Jialu Weng, Lina Wu, Yizhe Ma, Ziyue Wang, Wenzhang Jin and Bicheng Chen

International Journal of Pharmaceutics: X, 2024, 8, 100278
DOI: 10.1016/j.ijpx.2024.100278

Multifunctional cell membranes-based nano-carriers for targeted therapies: a review of recent trends and future perspective

Mo Li, Qiushi Guo, Chongli Zhong and Ziyan Zhang

Drug Delivery, 2023, 30
DOI: 10.1080/10717544.2023.2288797

Cell membrane-coated nanoparticles: A new frontier in atherosclerosis therapy

Nasrullah Jan, Rania M. Yehia, Mahir Mohammed, Mazin B. Ahmed, Hajeltom G. Seedahmed, Hassan Shah, Syed Faisal Badshah and Guixiu Shi

Chemical Engineering Journal, 2025, 524, 169183
DOI: 10.1016/j.cej.2025.169183

Cell Membrane-Derived Nanovehicles for Targeted Therapy of Ischemic Stroke: From Construction to Application

Cui Hao, Ma Sha, Yang Ye and Chengxiao Wang

Pharmaceutics, 2023, 16, 6
DOI: 10.3390/pharmaceutics16010006

Clot structure-based physical-matching design of platelet cloaking nano-delivery system facilitates specific arteriovenous thrombolysis

Yujiao Wang, Linwen Lv, Haojun Liang, Wei Liang, Ziteng Chen, Jiacheng Li, Sen Liu, Fan Hu, Junyu Zhu, Qiuyang Liu, Zhijie Wang, Ya-nan Chang, Juan Li, Min Li, Guiying Li, Kui Chen and Gengmei Xing

Chemical Engineering Journal, 2022, 441, 135982
DOI: 10.1016/j.cej.2022.135982

A microthrombus-driven fixed-point cleaved nanosystem for preventing post-thrombolysis recurrence via inhibiting ferroptosis

Mengjuan Sun, Chang Liu, Ji Liu, Jing Wen, Tianjiao Hao, Daquan Chen and Yan Shen

Journal of Controlled Release, 2024, 367, 587
DOI: 10.1016/j.jconrel.2024.01.070

Advanced drug delivery system against ischemic stroke

Shanshan Zhang, Yuan Zhou, Ruoqi Li, Zhong Chen and Xiang Fan

Journal of Controlled Release, 2022, 344, 173
DOI: 10.1016/j.jconrel.2022.02.036

Progress of nanomaterials in the treatment of thrombus

Yetong Shen, Yang Yu, Xin Zhang, Bo Hu and Ning Wang

Drug Deliv. and Transl. Res., 2024, 14, 1154
DOI: 10.1007/s13346-023-01478-6

Smart micro/nanorobots for drug delivery in the brain

Di Shi, Xiang Wang, Yulin Deng, Huaijuan Zhou, Yilong Wang, Paul K. Chu and Jinhua Li

Progress in Materials Science, 2026, 155, 101533
DOI: 10.1016/j.pmatsci.2025.101533

Cyclo(RGD) peptide-decorated silver nanoparticles with anti-platelet potential for active platelet-rich thrombus targeting

Yuanyuan Li, Yangye Jin, Xiaofeng He, Yonghui Tang, Min Zhou, Wenjing Guo and Wenjun Miao

Nanomedicine: Nanotechnology, Biology and Medicine, 2022, 41, 102520
DOI: 10.1016/j.nano.2022.102520

Nanocarrier-Based Management of Venous and Arterial Thrombosis

Mihai Ștefan Cristian Haba, Dragomir N. Șerban, Ionela Lăcrămioara Șerban, Ivona Maria Tudorancea, Raluca Maria Haba, Minela Aida Mărănducă, Daniela Maria Tănase, Radu Iliescu and Ionuț Tudorancea

Crystals, 2022, 12, 450
DOI: 10.3390/cryst12040450

Enhancing cardio-cerebrovascular therapy through biomimetic platelet membrane coating

Akshara S, Sanjane F A, Tanzil Rubab, Nikitha Shalom R and Shoba Narayan

Bioinspired, Biomimetic and Nanobiomaterials, 2025, 14, 1
DOI: 10.1680/jbibn.23.00042

Biomembrane-Modified Biomimetic Nanodrug Delivery Systems: Frontier Platforms for Cardiovascular Disease Treatment

Yunan Gu, Lixin Du, Yuxin Wu, Juan Qin, Xiang Gu, Zhihua Guo and Ya Li

Biomolecules, 2024, 14, 960
DOI: 10.3390/biom14080960

Fibrin-targeted ROS-scavenging micelles with photothermal and NO delivery for thrombolysis and post-thrombotic vascular remodeling

Yueming Xue, Cheng Li, Jiale Si, Guopu Huang, Shiming Zhao, Yansong Dong, Qinghao Zhou, Yuanyuan Ji and Zhishen Ge

Journal of Controlled Release, 2025, 386, 114159
DOI: 10.1016/j.jconrel.2025.114159

Targeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms

Nisakorn Yodsanit, Takuro Shirasu, Yitao Huang, Li Yin, Zain Husain Islam, Alexander Christopher Gregg, Alessandra Marie Riccio, Runze Tang, Eric William Kent, Yuyuan Wang, Ruosen Xie, Yi Zhao, Mingzhou Ye, Jingcheng Zhu, Yi Huang, Nicholas Hoyt, Mengxue Zhang, John A. Hossack, Morgan Salmon, K. Craig Kent, Lian-Wang Guo, Shaoqin Gong and Bowen Wang

Bioactive Materials, 2023, 26, 52
DOI: 10.1016/j.bioactmat.2023.02.009

Biomembrane‐inspired design of medical micro/nanorobots: From cytomembrane stealth cloaks to cellularized Trojan horses

Jinhua Li, Huaijuan Zhou, Chun Liu, Shuailong Zhang, Ran Du, Yulin Deng and Xuenong Zou

Aggregate, 2023, 4
DOI: 10.1002/agt2.359

Platelet-inspired targeting delivery for coronary heart disease

Yu Jiang, Zhi-Yao Wei, Zhi-Feng Song and Hai-Yan Qian

Heliyon, 2024, 10, e27166
DOI: 10.1016/j.heliyon.2024.e27166

Platelet-Covered Nanocarriers for Targeted Delivery of Hirudin to Eliminate Thrombotic Complication in Tumor Therapy

Kai Zhang, Zhaoyu Ma, Shuting Li, Weiyun Zhang, Mohamed Frahat Foda, Yanli Zhao and Heyou Han

ACS Nano, 2022, 16, 18483
DOI: 10.1021/acsnano.2c06666

ROS-Suppression Nanoplatform Combined Activation of STAT3/Bcl-2 Pathway for Preventing Myocardial Infarction in Mice

Nan Hu, Meng Sun, Nan Lv, Yangyang Gao, Xiaohong Fu, Dayi Xing, Xiang Guo, Shaodong Zhai and Ruiping Zhang

ACS Appl. Mater. Interfaces, 2024, 16, 12188
DOI: 10.1021/acsami.3c16735

On-Site Self-Penetrating Nanomedicine Enabling Dual-Priming Drug Activation and Inside-Out Thrombus Ablation

Hongyuan Zhang, Jing Wang, Haonan Wu, Yuequan Wang, Shenwu Zhang, Jin Sun, Zhonggui He and Cong Luo

ACS Nano, 2024, 18, 34683
DOI: 10.1021/acsnano.4c09986

Biomimetic lipid nanoparticles for homologous-targeting and enhanced photodynamic therapy against glioma

Fengtian Zhang, Changlong Wen, Yu Peng, Zhihao Hu, Shikeng Zheng, Weiliang Chen and Lijuan Wen

European Journal of Pharmaceutical Sciences, 2023, 190, 106574
DOI: 10.1016/j.ejps.2023.106574

Engineering Platelet Membrane Imitating Nanoparticles for Targeted Therapeutic Delivery

Shradha B. Adhalrao, Kisan R. Jadhav, Prashant L. Patil, Vilasrao J. Kadam and Kasekar Nirmal M.

CPB, 2024, 25, 1230
DOI: 10.2174/1389201024666230804140926

Thrombus-Targeting Polymeric Nanocarriers and Their Biomedical Applications in Thrombolytic Therapy

Qixiao Guan and Hongjing Dou

Front. Physiol., 2021, 12
DOI: 10.3389/fphys.2021.763085

Biomimetic Platelet Nanomotors for Site-Specific Thrombolysis and Ischemic Injury Alleviation

Yan-Ting Chen, Chia-Hung Liu, Wen-Yu Pan, Pei-Ru Jheng, Yves S. Y. Hsieh, Thierry Burnouf, Yu-Jui Fan, Chia-Che Chiang, Tzu-Yin Chen and Er-Yuan Chuang

ACS Appl. Mater. Interfaces, 2023, 15, 32967
DOI: 10.1021/acsami.3c06378

Poly(L-Lactic Acid) Composite with Surface-Modified Magnesium Hydroxide Nanoparticles by Biodegradable Oligomer for Augmented Mechanical and Biological Properties

Seung-Woon Baek, Duck Hyun Song, Ho In Lee, Da-Seul Kim, Yun Heo, Jun Hyuk Kim, Chun Gwon Park and Dong Keun Han

Materials, 2021, 14, 5869
DOI: 10.3390/ma14195869

An Ultrasmall Cu/Cu2O Nanoparticle-Based Diselenide-Bridged Nanoplatform Mediating Reactive Oxygen Species Scavenging and Neuronal Membrane Enhancement for Targeted Therapy of Ischemic Stroke

Jianglong Kong, Rui Zou, Runxuan Chu, Nan Hu, Jiawen Liu, Yuting Sun, Xiaohan Ge, Meiru Mao, Hongrui Yu and Yi Wang

ACS Nano, 2024, 18, 4140
DOI: 10.1021/acsnano.3c08734

Surface Bio‐engineered Polymeric Nanoparticles

Laura Libnan Haidar, Marcela Bilek and Behnam Akhavan

Small, 2024, 20
DOI: 10.1002/smll.202310876

GOx-Powered Janus Platelet Nanomotors for Targeted Delivery of Thrombolytic Drugs in Treating Thrombotic Diseases

Xiaojuan Fang, Huihui Ye, Keqing Shi, Kaicheng Wang, Yueyue Huang, Xianwei Zhang and Jingye Pan

ACS Biomater. Sci. Eng., 2023, 9, 4302
DOI: 10.1021/acsbiomaterials.3c00387

Advances in cerebral edema research and targeted drug delivery systems

Peng Fu, Xiu-fen Yang, Wen-wen Deng, Jiang-nan Yu and Xi-ming Xu

European Journal of Pharmacology, 2025, 1000, 177744
DOI: 10.1016/j.ejphar.2025.177744

Recent Advances in Cell‐Based Nanotherapy for Cardiovascular Diseases

Xuefang Hao and Qian Li

Macromolecular Bioscience, 2023, 23
DOI: 10.1002/mabi.202200537

Multi-enzyme mimetic iridium nanozymes-based thrombus microenvironment-modulated nanoplatform for enhanced thrombolytic therapy

Meng Huang, Yuda Zhu, Guang Xin, Yilan Wang, Fan Li, Shiyi Li, Yuman Dong, Kun Zhang, Lijuan Feng, Li Tang, Boli Zhang and Wen Huang

Chemical Engineering Journal, 2023, 470, 144156
DOI: 10.1016/j.cej.2023.144156