Issue 100, 2014
From the journal:

Chemical Communications

Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection†

Tarun Kumar Sharma,*ab   Rajesh Ramanathan,a   Pabudi Weerathunge,a   Mahsa Mohammadtaheri,a   Hemant Kumar Daima,ac   Ravi Shuklaa  and  Vipul Bansal*a  

* Corresponding authors

a Ian Potter NanoBioSensing Facility, NanoBiotechnology Research Laboratory, School of Applied Science, RMIT University, GPO Box 2476V, Melbourne VIC 3001, Australia
E-mail: vipul.bansal@rmit.edu.au
Fax: +61 3 99253747
Tel: +61 3 99252121

b Centre for Biodesign and Diagnostics, Translational Health Science and Technology Research Institute, Gurgaon, Haryana 247667, India
E-mail: tarun@thsti.res.in

c Department of Biotechnology, Siddaganga Institute of Technology, Tumkur, Karnataka 572103, India

Abstract

A new ultrafast and highly sensitive ‘turn-off/turn-on’ biosensing approach that combines the intrinsic peroxidase-like activity of gold nanoparticles (GNPs) with the high affinity and specificity of a ssDNA aptamer is presented for the efficient detection of a model small molecule kanamycin.

Graphical abstract: Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection

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Article information

DOI
https://doi.org/10.1039/C4CC07275H
Article type
Communication
Submitted
15 Sept 2014
Accepted
30 Sept 2014
First published
06 Oct 2014

Chem. Commun., 2014,50, 15856-15859

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Aptamer-mediated ‘turn-off/turn-on’ nanozyme activity of gold nanoparticles for kanamycin detection

T. K. Sharma, R. Ramanathan, P. Weerathunge, M. Mohammadtaheri, H. K. Daima, R. Shukla and V. Bansal, Chem. Commun., 2014, 50, 15856 DOI: 10.1039/C4CC07275H

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